Antibacterial activity of Eurya acuminata DC. leaves ethanol extract against Pseudomonas aeruginosa and Staphylococcus aureus

Abstract

Antibiotics as modern medicine in the treatment of infections have experienced resistance due to irrational use. Traditional medicinal plants have many chemical components that have been used to treat various diseases including skin diseases, one of them is Eurya acuminata DC. The study aimed to determine the optimum concentration of E. acuminata leaves extract against Pseudomonas aeruginosa and Staphylococcus aureus. This antibacterial test was carried out using the diffusion and dilution method. The concentrations of ethanol extract used were 20%, 40%, 60%, 80% and fresh extract. The highest antibacterial activity of E. acuminata leaves ethanol extract was by diffusion against P. aeruginosa and S. aureus were present at a concentration of 60% with an inhibition zone by 11.72 mm and 10.84 mm, respectively. The MIC and MBC values ​​of the ethanol extract of E. acuminata leaves were not found. It was concluded that E. acuminata leaves ethanol extract might be an alternative antibacterial agent because it was able to inhibit P. aeruginosa and S. aureus.