2012
DOI: 10.1166/sam.2012.1402
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Antibacterial Activity of Graphene Oxide Nanosheets

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Cited by 126 publications
(86 citation statements)
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“…41 Oxidative stress is due to the overproduction of reactive oxygen species in the bacterial cells by the nanoparticle exposure. 40 The mechanism of antibacterial activity of the prepared TiO 2 nanopaint is due to direct interaction between the bacteria and paint surface which can result in the membrane stress and cell death. The cell death by the oxidative stress can be ruled out in this study since ROS related mechanistic pathways for cell death are available only in free nanoparticles suspended in solution.…”
Section: Discussionmentioning
confidence: 99%
“…41 Oxidative stress is due to the overproduction of reactive oxygen species in the bacterial cells by the nanoparticle exposure. 40 The mechanism of antibacterial activity of the prepared TiO 2 nanopaint is due to direct interaction between the bacteria and paint surface which can result in the membrane stress and cell death. The cell death by the oxidative stress can be ruled out in this study since ROS related mechanistic pathways for cell death are available only in free nanoparticles suspended in solution.…”
Section: Discussionmentioning
confidence: 99%
“…9 The underlying mechanism in the observed case is most likely due to different degrees of hydrophobichydrophobic and ionic-ionic interactions between the PEM and the bacteria cell wall. The thick negatively charged peptidoglycan layer in case of gram positive bacteria is unlikely to adsorb on a negatively charged substrate, compared to a partly uncharged cell wall in case of gram negative bacteria.…”
Section: Effect Of Different Surfacesmentioning
confidence: 91%
“…The mechanism for the preference of a certain bacteria type in the observed is therefore very different from the one of graphene films, which's selectivity is due to the production of oxygen radicals. 9 Interestingly the reversed phenomena can be monitored for cross-linked negative charge terminated films, which prefer no bacteria type. The reason for this is the amino group in the cross-linking agent that influences not only the mechanical properties but also the PEM structure The PSS-PDDA films showed for both types of surface charge a very selective settlement of gram positive bacteria.…”
Section: Effect Of Different Surfacesmentioning
confidence: 99%
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“…Owing to nano-sizes, it may interfere with several chemical processes taking place in cells. Such interactions may cause oxidative stress leading to bacterial cell death [19][20][21][22].…”
Section: Introductionmentioning
confidence: 99%