Antibacterial Activity of Green-Synthesized Silver Nanoparticles Using Areca catechu Extract against Antibiotic-Resistant Bacteria

Abstract

In this work, the antibacterial activity of silver nanoparticles (AgNPs) synthesized using Areca catechu extracts against three species of antibiotic-susceptible and three species of resistant bacteria was investigated. The effects of this plant were more promising when compared with other medicinal plants tested. The hydrothermal extract of Areca catechu was mixed with silver nitrate to synthesize AgNPs. The synthesized particle characteristics were analyzed by UV–Vis spectrophotometry, scanning electron microscopy (SEM), dynamic light scattering (DLS), and Fourier-transform infrared spectroscopy (FT-IR). Minimum inhibitory concentration and minimum bactericidal concentration tests were conducted to confirm antibacterial activity and the results showed that AgNPs synthesized using Areca catechu extracts effectively inhibited the growth of bacterial species. Moreover, the SEM images of the bacterial species treated with AgNPs synthesized with Areca catechu extracts showed that clusters of AgNPs were attached to the surface of the bacterial cell wall, which could induce destruction of the cell membranes. The results suggest that AgNPs synthesized with Areca catechu extracts have the potential to treat antibiotic-resistant bacteria known as the major cause of nosocomial infections.

Systematic Evaluation of Antioxidant Efficiency and Antibacterial Mechanism of Bitter Gourd Extract Stabilized Silver Nanoparticles

“…Moreover, hemolytic evaluations of BG-AgNPs against human RBCs demonstrated that the BG-mediated AgNPs were highly biocompatible to mammalian cells. To our best knowledge, the inhibition efficiency of A-BG-AgNPs against drug-resistant Gram-negative bacterial strains is superior to the other plant extract-mediated AgNPs from previous studies [ 72 , 73 ].…”

Toxicity of Ulva lactuca and green fabricated silver nanoparticles against mosquito vectors and their impact on the genomic DNA of the dengue vector Aedes aegypti

“…This implies that green‐synthesised nanoparticles are more active against microbial strains than are crude extracts. It is evident from earlier research that AgNPs‐synthesised nanoparticles from Areca catechu exhibited potential activity against antibiotic‐resistant bacteria [35]. The compound phlorotannin from brown seaweeds also exhibits good antiviral, antibacterial, antifungal, and larvicidal activities [36].…”

Green synthesis of silver nanoparticles through oil: Promoting full-thickness cutaneous wound healing in methicillin-resistant Staphylococcus aureus infections

“…To obtain silver nanoparticles, several analytical techniques were utilized, including UV-vis, TEM, XRD, zeta potential, and FTIR. In general, the sizes of AgNPs in green-route were larger compared with the particles synthesized by chemical methods ( Choi et al, 2021 ). Priyanka Basera reported that AgNPs prepared by Cymbopogon citratus were about 35 nm ( Khan et al, 2017 ).…”