Antibacterial activity of honey from the Australian stingless bee Trigona carbonaria

Irish, Julie; Carter, Dee; Blair, Shona E.; Heard, Tim A.

doi:10.1016/j.ijantimicag.2008.02.012

Cited by 35 publications

(36 citation statements)

References 6 publications

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“…An entomological study by Stow et al [74] has indicated that cuticular antimicrobial compounds that have been secreted from stingless bee honey are responsible for preventing microbial growth. From this finding, Irish et al [64] have postulated that the non-peroxide activity of stingless bee honey has a connection with the anatomical structure itself of the stingless bee. The non-peroxide activity has a more significant and substantial mechanism in antimicrobial action.…”

Section: Antimicrobial Role Of Stingless Bee Honeymentioning

confidence: 99%

“…Stingless bee honey can be used as an antibacterial ingredient in pharmaceutical formulations since it possesses antimicrobial and antiseptic properties. The antimicrobial activity of stingless bee honey was validated by using the Kirby-Bauer antibiotic test, the agar dilution test, broth microdilution, and time-kill viability assays [10,64,65]. This study was supported by researchers from Brazil where they found that stingless bee honey has the ability to inhibit the growth of gram-positive and gram-negative bacteria [66].…”

Section: Antimicrobial Role Of Stingless Bee Honeymentioning

confidence: 99%

See 1 more Smart Citation

Stingless Bee Honey, the Natural Wound Healer: A Review

Jalil¹,

Kasmuri²,

Hadi³

2017

Skin Pharmacol Physiol

172

138

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Background: The stingless bee is a natural type of bee that exists in almost every continent. The honey produced by this bee has been widely used across time and space. The distinctive feature of this honey is that it is stored naturally in the pot (cerumen), thus contributing to its beneficial properties, especially in the wound healing process. Methods: In this article, several studies on stingless bee honey that pointed out the numerous therapeutic profiles of this honey in terms of its antioxidant, antimicrobial, anti-inflammatory, as well as moisturizing properties are reviewed. All of these therapeutic properties are related to wound healing properties. Results: Antioxidant in stingless bee honey could break the chain of free radicals that cause a detrimental effect to the wounded area. Furthermore, the antimicrobial properties of stingless bee honey could overcome the bacterial contamination and thus improve the healing rate. Moreover, the anti-inflammatory attribute in this honey could protect the tissue from highly toxic inflammatory mediators. The moisturizing properties of the honey could improve wound healing by promoting angiogenesis and oxygen circulation. Conclusion: The application of honey to the wound has been widely used since ancient times. As a result, it is essential to understand the pharmacological mechanism of the honey towards the physiology of the wounded skin in order to optimize the healing rate in the future.

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Section: Antimicrobial Role Of Stingless Bee Honeymentioning

confidence: 99%

Section: Antimicrobial Role Of Stingless Bee Honeymentioning

confidence: 99%

Stingless Bee Honey, the Natural Wound Healer: A Review

Jalil¹,

Kasmuri²,

Hadi³

2017

Skin Pharmacol Physiol

172

138

View full text Add to dashboard Cite

show abstract

“…The antimicrobial potential of honey from the Australian stingless bee Trigona carbonaria Smith, 1854 has also been reported. 12,13 The in vitro antioxidant, antibacterial, and antimutagenic capacities of an Ecuadorian honey from stingless bees have also been studied. 9 The genus Melipona Illiger, 1806 is strictly neotropical and comprises more than 60 species from Mexico to Argentina.…”

Section: Introductionmentioning

confidence: 99%

Topical Anti-Inflammatory Activity of a Monofloral Honey of Mimosa scabrella Provided by Melipona marginata During Winter in Southern Brazil

Borsato

Prudente²,

Döll-Boscardin³

et al. 2014

Journal of Medicinal Food

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Melipona marginata is an endangered species of stingless bee from Brazil that produces honey with particular physicochemical features and a remarkable exotic flavor. To the best of our knowledge, this is the first report devoted to exploring the medicinal potential of this honey. Thus, the aim of this paper was to investigate the potential anti-inflammatory activity of honey extract from M. marginata on skin inflammation. The honey sample was classified as a monofloral honey of Mimosa scabrella. The presence of 11 phenolic compounds as kaempferol and caffeic acid was detected using the high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry (HPLC-UV-ESI-MS) method. The anti-inflammatory activity was measured using a 12-O-tetradecanoylphorbol-13-acetate-induced ear edema model of inflammation in mice. The topical application of the M. marginata honey extract (1.0 mg/ear) was able to reduce ear edema with an inhibitory effect of 54 ± 5%. This extract decreased the myeloperoxidase activity in 75 ± 3%, which suggests a lower leucocyte infiltration that was confirmed by histological analysis. This extract also provided a reduction of 55 ± 14% in the production of reactive oxygen species. This anti-inflammatory activity could be due to a synergic effect of the phenolic compounds identified in the honey sample. Taken together, these results open up new possibilities for the use of M. marginata honey extract in skin disorders.

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“…However, the botanical origin of honey has the greatest influence on its antioxidant activity [5]. Recently, honey has been tested and approved scientifically for its functional and biological properties such as anti-oxidant, anti-inflammatory, anti-bacterial, anti-viral, anti-ulcerous activities and anti-cancer properties [4], [6]–[11].…”

Section: Introductionmentioning

confidence: 99%

Polish Natural Bee Honeys Are Anti-Proliferative and Anti-Metastatic Agents in Human Glioblastoma multiforme U87MG Cell Line

et al. 2014

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Honey has been used as food and a traditional medicament since ancient times. However, recently many scientists have been concentrating on the anti-oxidant, anti-proliferative, anti-inflammatory and other properties of honey. In this study, we investigated for the first time an anticancer effect of different honeys from Poland on tumor cell line - glioblastoma multiforme U87MG. Anti-proliferative activity of honeys and its interferences with temozolomide were determined by a cytotoxicity test and DNA binding by [H3]-thymidine incorporation. A gelatin zymography was used to conduct an evaluation of metalloproteinases (MMP-2 and MMP-9) expression in U87MG treatment with honey samples. The honeys were previously tested qualitatively (diastase activity, total phenolic content, lead and cadmium content). The data demonstrated that the examined honeys have a potent anti-proliferative effect on U87MG cell line in a time- and dose-dependent manner, being effective at concentrations as low as 0.5% (multifloral light honey - viability 53% after 72 h of incubation). We observed that after 48 h, combining honey with temozolomide showed a significantly higher inhibitory effect than the samples of honey alone. We observed a strong inhibition of MMP-2 and MMP-9 for the tested honeys (from 20 to 56% and from 5 to 58% compared to control, respectively). Our results suggest that Polish honeys have an anti-proliferative and anti-metastatic effect on U87MG cell line. Therefore, natural bee honey can be considered as a promising adjuvant treatment for brain tumors.

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Antibacterial activity of honey from the Australian stingless bee Trigona carbonaria

Cited by 35 publications

References 6 publications

Stingless Bee Honey, the Natural Wound Healer: A Review

Stingless Bee Honey, the Natural Wound Healer: A Review

Topical Anti-Inflammatory Activity of a Monofloral Honey of Mimosa scabrella Provided by Melipona marginata During Winter in Southern Brazil

Polish Natural Bee Honeys Are Anti-Proliferative and Anti-Metastatic Agents in Human Glioblastoma multiforme U87MG Cell Line

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