Antibacterial Activity of Leaf Extract of Annona muricata and Simarouba glauca on Enterococcus faecalis

Mathew, Jain; George, Reshmi; Theruvil, Robin; Padavil, Tobin C; Tomy, Lincy; Kurian, Anil

doi:10.5005/jp-journals-10024-1906

Cited by 11 publications

(11 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…21 In this study ethanolic extract showed maximum zone of inhibition against both organisms. Similar result is observed in study by Mathew et al 17 in which zone of inhibition is seen against E. faecalis.…”

Section: Discussionsupporting

confidence: 91%

“…In the present study, significant zone of inhibition was observed against both test microbes. But a study by Mathew et al 17 reported no zone of inhibition against E. faecalis. This may be due to difference in extract preparation and E. faecalis strain in this study, which is a clinical isolate that may have posed individual characteristics with regard to resistance and tolerance toward various chemical agents.…”

Section: Discussionmentioning

confidence: 98%

See 1 more Smart Citation

Evaluation of Antimicrobial Activity of Leaf Extracts of Moringa, Laxmitaru, Mullatha, and Communist Paccha against Enterococcus faecalis and Candida albicans : An in vitro Study

Jeeva¹,

Gopinathan²,

Jaini³

et al. 2018

IJPCDR

View full text Add to dashboard Cite

Introduction: General health depends on the oral health. A vast majority of synthetic antimicrobial agents were developed to control oral infections. Side effects and drug resistance of these antimicrobial agents became barrier in successful treatment. Global scenario is now changing toward the use of nontoxic and eco-friendly products. Medicinal plant extracts are emerging as alternative to synthetic drugs. Aim: This in vitro study evaluated antimicrobial activity of leaf extracts of Moringa, Laxmitaru, Mullatha, and Communist paccha against Enterococcus faecalis and Candida albicans. Materials and methods: Ethanolic leaf extracts of Moringa, Laxmitaru, Mullatha, and Communist paccha were prepared. E. faecalis and C. albicans were cultured on agar plates and leaf extracts were added. The plates were incubated at 37°C for 24 hours. Ethanol was used as positive control. Agar well diffusion test was performed and zone of inhibition was calculated in millimeter. Result was analyzed statistically. Results: Ethanolic extract of Mullatha leaf showed maximum zone of inhibition followed by Moringa, Laxmitaru, and Communist paccha against E. faecalis and C. albicans respectively Conclusion: Study suggested the use of leaf extracts of Moringa, Laxmitaru, Mullatha, and Communist paccha as endodontic irrigant and as antifungal agent in oral candidal infections.

show abstract

Section: Discussionsupporting

confidence: 91%

Section: Discussionmentioning

confidence: 98%

Evaluation of Antimicrobial Activity of Leaf Extracts of Moringa, Laxmitaru, Mullatha, and Communist Paccha against Enterococcus faecalis and Candida albicans : An in vitro Study

Jeeva¹,

Gopinathan²,

Jaini³

et al. 2018

IJPCDR

View full text Add to dashboard Cite

show abstract

“…Mathew et al examined aqueous extracts of leaves from graviola and Simarouba glauca on the dental root canal pathogen Enterococcus faecalis [ 133 ]. These authors reported that the graviola extract, but not the S. glauca extract, was as effective against E. faecalis in vitro as the sodium hypochlorite (1% bleach) reference disinfectant, providing a possible alternative for root canal irrigation.…”

Section: Antimicrobial and Antiparasitic Potentialsmentioning

confidence: 99%

Anticancer Properties of Graviola (Annona muricata): A Comprehensive Mechanistic Review

Rady

Bloch

Chamcheu

et al. 2018

Oxidative Medicine and Cellular Longevity

127

View full text Add to dashboard Cite

Graviola (Annona muricata) is a small deciduous tropical evergreen fruit tree, belonging to the Annonaceae family, and is widely grown and distributed in tropical and subtropical regions around the world. The aerial parts of graviola have several functions: the fruits have been widely used as food confectionaries, while several preparations, especially decoctions of the bark, fruits, leaves, pericarp, seeds, and roots, have been extensively used in traditional medicine to treat multiple ailments including cancers by local communities in tropical Africa and South America. The reported therapeutic benefits of graviola against various human tumors and disease agents in in vitro culture and preclinical animal model systems are typically tested for their ability to specifically target the disease, while exerting little or no effect on normal cell viability. Over 212 phytochemical ingredients have been reported in graviola extracts prepared from different plant parts. The specific bioactive constituents responsible for the major anticancer, antioxidant, anti-inflammatory, antimicrobial, and other health benefits of graviola include different classes of annonaceous acetogenins (metabolites and products of the polyketide pathway), alkaloids, flavonoids, sterols, and others. This review summarizes the current understanding of the anticancer effects of A. muricata and its constituents on diverse cancer types and disease states, as well as efficacy and safety concerns. It also includes discussion of our current understanding of possible mechanisms of action, with the hope of further stimulating the development of improved and affordable therapies for a variety of ailments.

show abstract

“…The results of antimicrobial activity of A. niger strain SH3 extract, seed extract and in combination were compared with positive control either Ampicillin or Amphotericin B for evaluating their relative percentage inhibition, where A. niger strain SH3 extract exhibits maximum relative percentage inhibition against P. aeruginosa (36%), (32.65%) against S. aureus (31.37%) against E. coli followed by seed extract and combined extract showed the least percentage (Table 5). [20] proved the effectiveness of A. muricata leaf extract as an antibacterial agent against Enterococcus faecalis.…”

Section: Antimicrobial Activitymentioning

confidence: 92%

Antimicrobial Activity of Terpenoids Extracted from Annona muricata Seeds and its Endophytic Aspergillus niger Strain SH3 Either Singly or in Combination

Abdelrahman¹,

Saad-Hussein²,

Beshir³

et al. 2019

Open Access Maced J Med Sci

View full text Add to dashboard Cite

BACKGROUND: Annona muricata (Soursop) has an antimicrobial activity toward various pathogenic microorganisms which support its ethnomedicinal for the treatment of many infectious diseases. AIM: Aim of the present study to evaluate the relation between antimicrobial activities of terpenoids extracted from different soursop parts with the isolated endophytic fungi. METHODS: Endophytic fungal species of pulp and peel of Annona fruit along with those of seeds were isolated. Salkowski test was used for qualitative screening of terpenoids in plant and the isolated endophytic Aspergillus niger strain SH3. RESULTS: Endophytic A. niger strain SH3 and Annona seed extract showed high terpenoid content indicated by the high intensity of reddish-brown colour. GC/Mass analysis revealed six compounds of terpenoids from endophytic A. niger strain SH3 extract and four compounds from seed extract with different retention times. The antimicrobial assay was performed using A. niger strain SH3 extract and Annona seed extract singly or in combinations against S. aureus, P. aeruginosa, E. coli and C. albicans. CONCLUSION: The results revealed the significant antimicrobial activity of both extracts. However, the combined extract showed some reduction in antimicrobial activity which could be attributed to the antagonistic effect exhibited by their constituents.

show abstract

Antibacterial Activity of Leaf Extract of Annona muricata and Simarouba glauca on Enterococcus faecalis

Cited by 11 publications

References 15 publications

Evaluation of Antimicrobial Activity of Leaf Extracts of Moringa, Laxmitaru, Mullatha, and Communist Paccha against Enterococcus faecalis and Candida albicans : An in vitro Study

Evaluation of Antimicrobial Activity of Leaf Extracts of Moringa, Laxmitaru, Mullatha, and Communist Paccha against Enterococcus faecalis and Candida albicans : An in vitro Study

Anticancer Properties of Graviola (Annona muricata): A Comprehensive Mechanistic Review

Antimicrobial Activity of Terpenoids Extracted from Annona muricata Seeds and its Endophytic Aspergillus niger Strain SH3 Either Singly or in Combination

Contact Info

Product

Resources

About