Antibacterial Activity of Polyscias Scutellaria Fosberg Against Acinetobacter Sp.

Abstract

Objective: Polyscias scutellaria Fosberg as one of the indigenous plants from Indonesia has been used as traditional medicines for several ailments, such as reduce body odor. However, there is no scientific research to verify this property. This study aimed to evaluate the antibacterial activity of P. scutellaria Fosberg against bacteria that cause body odor.Methods: Since body odor is caused by activities of bacteria that live in the armpits, bacteria from human armpit were isolated and identified as Acinetobacter sp. The bacteria have the potential to be pathogenic and resistant to common antibiotics. P. scutellaria was extracted using different solvents, i.e., hexane, ethyl acetate, and methanol. Using these extracts, the antibacterial activity of P. scutellaria against Acinetobacter sp. was tested through well diffusion and colony-forming unit methods.Results: Hexane and ethyl acetate fractions of P. scutellaria extract showed strong antibacterial activities against Acinetobacter sp., while methanol fraction did not exhibit any antibacterial activity against these bacteria.Conclusion: P. scutellaria extract has the potential to be used as an antibacterial agent against Acinetobacter sp. on human armpit.

Determination of Total Flavonoid Level and Antioxidant Activity of Ethyl Acetate Fraction of Mangkokan Leaf Extract (Nothopanax scutellarium [Burm.f] Merr.)

“…Flavonoids are the largest phenolic group of compounds found in nature and are a source of potent antioxidants because they have an ideal chemical structure that can counteract free radicals. Antioxidants play an important role in protection against oxidative cell damage that can lead to several disease conditions, such as Alzheimer's disease, cancer, heart disease, and are also associated with chronic inflammation [5].…”

“…such as calcium, oxalate, peroxidase, amygdalin, phosphorus, iron, fat, protein, Vitamins A, B1, C, saponins, tannins, flavonoids, alkaloids, and terpenoids [2], [3], [4]. Meanwhile, it has been scientifically proven that the leaves of the Mangkokan have anti-fungal activity [6], antioxidant [3], antibacterial [5], and wound healing. This is because the mangrove leaves contain flavonoid compounds and other compounds that can provide pharmacological activity [2].…”

Effect of Mangkokan (Polyscias scutellaria) Leaf Extract on Blood Sugar Levels in Alloxan-Induced Male White Rats

“…The maceration process is carried out 3 times, then the filtrate of each maceration and re-maceration evaporates with a rotary evaporator at a temperature of 70oC and then followed by drying using an oven at 40oC to become a thick extract. 12,13 In this research, the phytochemical test used a modification of the Fansworth method consisting of identification of phenols, steroids/ triterpenoids, terpenoids, saponins, flavonoids, tannins and alkaloids. 14 All male wistar rats were housed in several standard polypropylene cages under an environment suitable for conditions with maintained light-dark cycles.…”