Antibacterial activity of Rosmarinus officinalis L. alone and in combination with cefuroxime against methicillin–resistant Staphylococcus aureus

Jarrar, Naser; Abu-Hijleh, Awni; Adwan, Kamel

doi:10.1016/s1995-7645(10)60049-1

Cited by 65 publications

(45 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The minimum bactericidal concentrations (MBCs) were usually equal to or double MICs. The antimicrobial activity of combinations of the ethanol extract of rosemary and cefuroxime indicated their synergistic effects against all MRSAs (28).…”

Section: Discussionmentioning

confidence: 98%

Antifungal Effect of the Extract of the Plants Against Candida albicans

et al. 2016

View full text Add to dashboard Cite

Background: Medicinal plants are widely used throughout the world. Since these plants are known to have minimal side effects, many people embrace them. This study aims to investigate the antifungal effects of the extracts of the plants against Candida albicans. Methods: The extracts of Echinophora platyloba, Peganum harmala, Heracleum persicum and Rosmarinus officinalis were prepared using a rotary device. The inhibitory concentration against Candida albicans was determined using incubation in media. Results:The results show that highest MIC of R. officinalis against C. albicans was 100 ppm and low MIC was 12.5 ppm against C. albicans (Table 1) and the highest MIC of E. platyloba against C. albicans was 150 ppm and low MIC was 12.5 ppm against C. albicans. The results of this study showed that by increasing the concentration of plant extracts inhibited by the fungus has also been increased. Futhermore, Heracleum persicum extract concentration inhibited growth of fungal ppm 25 while Peganum harmala extract concentration inhibited growth ppm 50. Conclusions:The results showed good antifungal activity Peganum harmala, Echinophora platyloba, Rosmarinus officinalis and Heracleum persicum has expressed Feb plants can be used to treat infections caused by these.

show abstract

Section: Discussionmentioning

confidence: 98%

Antifungal Effect of the Extract of the Plants Against Candida albicans

et al. 2016

View full text Add to dashboard Cite

show abstract

“…Embora diversos estudos relatem a atividade antimicrobiana da Rosmarinus officinalis L., (ANGIONI et al, 2004;OLUWATUYI;KAATZ;GIBBONS, 2004;BOZIN et al, 2007;LUQMAN et al, 2007;van VUUREN;SULIMAN;VILJOEN, 2009;ZAGO et al, 2009;JARRAR;ABU-HIJLEH;ADWAN, 2010) nenhum trabalho foi encontrado durante a pesquisa utilizando o óleo essencial da planta estudada, como modulador de bactérias isoladas de alimentos resistentes aos antibióticos convencionais.…”

Section: Resultsunclassified

Avaliação do óleo essencial de alecrim (Rosmarinus officinalis L.) como modulador da resistência bacteriana

et al. 2012

View full text Add to dashboard Cite

ResumoDiversos microrganismos podem ser veiculados por alimentos causando doenças nos seres humanos. Os antibióticos comumente utilizados no tratamento dessas doenças têm apresentado baixo ou nenhum efeito, tendo em vista à resistência que muitos microrganismos têm adquirido. Diante deste quadro, o objetivo desta pesquisa foi avaliar o óleo essencial das folhas de Rosmarinus officinalis L. como modulador da resistência bacteriana a drogas. O óleo essencial foi obtido através de hidrodestilação em aparelho de Clevenger por 3h. Foram testadas 4 cepas de E.coli resistentes a Ampicilina (AMP) e a Tetraciclina (TET) e 4 cepas de Salmonella spp. resistentes a Nitrofurantoína (NIT). As cepas em suspensão escala MacFarland 0,5 foram inoculadas em agar Mueller Hinton, em seguida os discos dos antibióticos embebidos com 10 e 20μL do óleo de alecrim puro foram dispostos sobre as placas. Após 24h/37ºC foram medidos os halos ao redor dos discos. Todas as cepas avaliadas apresentaram susceptibilidade à ação combinada do óleo essencial com os antibióticos testados. Os resultados obtidos indicam ser promissora a utilização de óleo essencial de alecrim em associação com antibióticos no combate a bactérias patogênicas. Palavras-chave: Óleo essencial, alecrim, resistência bacteriana AbstractMicroorganisms can be transmitted by food causing diseases in humans. The antibiotics commonly used in treatment of these diseases have shown little or no effect, and in view of the resistance that many microorganisms have acquired. This study evaluated the essential oil leaves of Rosmarinus officinalis L. as a modulator of resistance bacterial drug. The essential oil was obtained by hydrodistillation in a Clevenger apparatus for 3 hours. We tested four strains of E.coli resistant ampicillin (AMP) and tetracycline (TET) and four strains of Salmonella spp. Resistant to nitrofurantoin (NIT). The strains in 0.5 MacFarland scale suspension were inoculated on Mueller Hinton agar, then soaked antibiotic disks with 10 and 20μL oil pure rosemary were placed on the plates. After 24h/37 º C were measured halos around the discs. All strains tested showed susceptibility to the combined action of essential oil with antibiotics tested. The results indicate that the use of promising rosemary essential oil in combination with antibiotics to combat pathogenic bacteria.

show abstract

“…Yap et al (2013) found the synergistic relationship between piperacillin/cinnamon bark oil, piperacillin/lavender oil, piperacillin/peppermint oil as well as meropenem/peppermint oil against ESBL-producing Escherichia coli. The antibacterial activity of the combinations of the ethanol extract of Rosmarinus officinalis and cefuroxime (Jarrar et al 2010), methanolic Thymus vulgaris extract, lemongrass and cardamom oils alone as well as a mixture with amoxacillin in 1:1 ratio (Abd El-Kalek & Mohammed 2012) showed synergistic effects against MRSA.…”

Section: Discussionmentioning

confidence: 99%

Essential oils and plant extracts with activity against oral microorganisms: prevention and treatment of oral diseases

Herman

Młynarczyk

2015

Israel J Plant Sci

View full text Add to dashboard Cite

The aim of this study was to compare the antimicrobial activity of essential oils and extracts of Salvia officinalis, Thymus vulgaris, Mentha piperita, Juniperus communis and Rosmarinus officinalis with antibiotics against physiological and pathological strains of microorganisms isolated from the oral cavity. The antibacterial and antifungal activities of essential oils, extracts and antibiotics were evaluated using the disc diffusion method. Essential oils exhibited higher inhibitory activity against physiological microflora and all tested pathogenic microorganism strains than those observed for antibiotics and plant extracts. Essential oils and ethanolic extracts of Thymus vulgaris were the most potent growth inhibitor of all microorganisms isolated from the oral cavity. Depending on the bacterial strain tested, Thymus vulgaris oil had 3–8 times higher inhibitory activity compared with all tested antibiotics and exhibited the same strength of antifungal activity as amfotericin and miconazol against Candida albicans. Essential oils and extracts may be useful in the prevention and treatment of oral diseases caused by oral microorganisms.

show abstract

Antibacterial activity of Rosmarinus officinalis L. alone and in combination with cefuroxime against methicillin–resistant Staphylococcus aureus

Cited by 65 publications

References 15 publications

Antifungal Effect of the Extract of the Plants Against Candida albicans

Antifungal Effect of the Extract of the Plants Against Candida albicans

Avaliação do óleo essencial de alecrim (Rosmarinus officinalis L.) como modulador da resistência bacteriana

Essential oils and plant extracts with activity against oral microorganisms: prevention and treatment of oral diseases

Contact Info

Product

Resources

About