Antibacterial Activity of Selected Australian Native Plant Extracts

doi:10.5580/8d1

Cited by 7 publications

(1 citation statement)

References 8 publications

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“…They found that Gram-positive strains were more sensitive than Gram-negative strains, and the most sensitive bacterium was S. aureus (26). In another study, the antibacterial activity of 39 methanolic extracts of 25 Australian herbs against two Gram-positive (Bacillus cereus and B. subtilis) and two Gram-negative (P. aeruginosa and Aeromonas hydrophila) was investigated, the results of which confirmed the sensitivity of Gram-positive bacteria (27).…”

Section: Discussionmentioning

confidence: 96%

Phytochemical Composition, Antibacterial, and Antibiofilm Activity of Malva sylvestris Against Human Pathogenic Bacteria

Fathi

Ghane

Pishkar

2021

Jundishapur J Nat Pharm Prod

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Background: Considering the increased rate of microbial resistance to antibiotics and chemical side effects of antibiotics, there is a need for an alternative antimicrobial agent with fewer complications. Medicinal plants are rich resources of phytochemical compounds with antibacterial activity that could fight off this problem. Objectives: The aim of this research was to investigate the chemical composition, antimicrobial, and antibiofilm properties of Malva sylvestris on some pathogenic bacteria. Methods: Antibacterial effect of the extract was assessed by the well diffusion and broth microdilution methods against Staphylococcus aureus, Enterococcus faecalis, Pseudomonas aeruginosa, Klebsiella pneumoniae, and Escherichia coli. The anti-biofilm property of the extract was also examined using the crystal violet assay. Finally, the chemical constituents and total phenols of the extract were determined by gas chromatography-mass spectrometry (GC-MS) and high-performance liquid chromatography (HPLC), respectively. Results: The methanolic extract of M. sylvestris showed antimicrobial activity against all tested Gram-negative and Gram-positive strains by the agar well diffusion method. The minimum inhibitory concentration (MIC) of the extract ranged from 21.9 ± 0.1 to 51.9 ± 0.5 mg/mL against the tested microorganisms. In addition, the minimum bactericidal concentration (MBC) spanned from 43.7 ± 0.1 to 85.8 ± 0.3 mg/mL. The biofilm inhibitory concentration (BIC50) of the extract was found to be 40 - 87 mg/mL against the tested bacteria. Analysis of the extract by GC-MS indicated that the most abundant compounds were 1-heptacosanol (38.41%), 17-Pentatriacontene (19.78%), and 6,9,12,15-docosatetraenoic acid, methyl ester (8.08%). High-performance liquid chromatography confirmed the presence of apigenin (6.84 ppm) and salicylic acid (1.5 ppm) as phenolic compounds in M. sylvestris methanolic extract. Conclusions: The results of this study represent the high potency of M. sylvestris extract as a source of biologically-active compounds for the development of future phytotherapeutic products with antibacterial and antibiofilm activity.

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Section: Discussionmentioning

confidence: 96%

Phytochemical Composition, Antibacterial, and Antibiofilm Activity of Malva sylvestris Against Human Pathogenic Bacteria

Fathi

Ghane

Pishkar

2021

Jundishapur J Nat Pharm Prod

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South African food and medicinal plant extracts as potential antimicrobial food agents

Cock

Vuuren

2015

J Food Sci Technol

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Many South African plants are used as both foods and traditional medicines for the treatment of diarrhoea and dysentery. A survey of edible plants for natural preservative/ functional food potential was undertaken on native South African plants with a history of medicinal usage. Sixty six extracts from 29 plant species were investigated for the ability to inhibit the growth of bacteria and fungi associated with food spoilage and food poisoning. Of these, 27 of the 29 plant species tested (93.1 %) inhibited the growth of at least one of the Gram-negative bacteria tested, compared with 23 of the 29 (79.3 %) plants tested inhibiting the growth of at least one Gram-positive bacterium, and seven of the 29 (24.1 %) plants tested inhibiting the growth of at least one fungal species. In general, the methanol plant extracts were better antimicrobial agents than the water extracts, as determined by the disc diffusion minimum inhibitory concentration (MIC) method. Syzygium cordatum, Terminalia pruinoides and Terminalia sericea extracts were particularly effective, with broadspectrum antimicrobial activity and MIC values generally significantly below 1000 μg/ml. Extracts of these plants were generally more potent antimicrobial agents than the control antibiotics, with significantly lower MIC values. All extracts exhibiting bacterial and fungal inhibitory activity were also shown to be non-toxic, or of low toxicity in the Artemia nauplii bioassay. The low toxicity of these extracts and their inhibitory bioactivity against bacteria and fungi associated with food spoilage/poisoning indicate their potential as natural food preservatives.

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Chemical composition and biological activities of leaf and fruit essential oils from Eucalyptus camaldulensis

Dogan

Kara

Bağcı

et al. 2017

Zeitschrift Für Naturforschung C

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The chemical composition of the essential oils from the leaves and fruit of Eucalyptus camaldulensis grown in Mersin, Turkey was analyzed using gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS) techniques. The biological activities (antibacterial and antifungal) were examined using the agar well diffusion method. The main leaf oil constituents were p-cymene (42.1%), eucalyptol (1,8-cineole) (14.1%), α-pinene (12.7%) and α-terpinol (10.7%). The main constituents of the fruit oil were eucalyptol (1,8-cineole) (34.5%), p-cymene (30.0%), α-terpinol (15.1%) and α-pinene (9.0%). Our results showed that both types of oils are rich in terms of monoterpene hydrocarbons and oxygenated monoterpenes. The leaf and fruit essential oils of E. camaldulensis significantly inhibited the growth of Gram-positive (Staphylococcus aureus and Bacillus subtilis) and Gram-negative (Escherichia coli and Streptococcus sp.) bacteria (p<0.05). The oils also showed fungicidal activity against Candida tropicalis and C. globrata. Leaf essential oils showed more activity than fruit essential oils, probably due to the higher p-cymene concentration in leaves.

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Antibacterial Activity of Selected Australian Native Plant Extracts

Cited by 7 publications

References 8 publications

Phytochemical Composition, Antibacterial, and Antibiofilm Activity of Malva sylvestris Against Human Pathogenic Bacteria

Phytochemical Composition, Antibacterial, and Antibiofilm Activity of Malva sylvestris Against Human Pathogenic Bacteria

South African food and medicinal plant extracts as potential antimicrobial food agents

Chemical composition and biological activities of leaf and fruit essential oils from Eucalyptus camaldulensis

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