"ANTIBACTERIAL ACTIVITY OF SILVER NANOPARTICLES COATED INTRAVASCULAR CATHETERS (AgNPs-IVC) AGAINST BIOFILM PRODUCING PATHOGENS "

Abstract

Nanotechnology encompasses the understanding of the fundamental physics, chemistry, biology and technology of nanometre-scale objects. The study of bactericidal nanomaterials is particularly timely considering the recent increase of new resistant strains of bacteria to the most potent antibiotics. In this present study, deals with antibacterial activity of green synthesized silver nanoparticles coated intravascular catheter (AgNPs-IVC) against biofilm producing human pathogens by Zone of inhibition (ZOI) standard microbiology assay. AgNPs-IVC shows excellent antibacterial activity against S. epidermidis and K. pneumoniae, ZOI around 42 mm and 36 mm. The prepared AgNPs-IVC confirms moderate antibacterial activity against S. aureus, E. coli and P. aeruginosa, ZOI around 31, 28 and 27 mm respectively. In addition, SPTT study reveals that the AgNPs-IVC showed a long duration of activities up to Day 8 th against K. pneumoniae and S. epidermidis. Hence, to the utilization of green synthesized silver nanoparticles coated biomedical products to prevent biofilm formation and act as widespread antibacterial materials.

Synthesis of Al/starch co-doped in CaO nanoparticles for enhanced catalytic and antimicrobial activities: experimental and DFT approaches

“…These peaks are attributed to the carbonic nature of calcite (CaCO 3 ) owing to trigger by the carbonic reaction of Ca(OH) 2 in which its generation stems from the hydration of clinker minerals. 28 St was ascribed to peaks at 10.95°, 13.02°, 18.08°, 22.99°and 43.01°. 29,30 Upon Al doping, extra peaks were observed at 50.9°( 110) and 54.3°(111), which correspond to the tetragonal structure of Al 2 O 3 (JCPDS card no.…”

Comparison of Ecotoxicity of Nickel and Iron Oxides and Their Nanoforms

“…Bacteria of the genus Azotobacter were more significantly affected by high concentrations (10,000 mg/kg) of nanoparticles of iron (66% of the control) and nickel oxides (75% of the control) than ordinary iron (81% of the control) and nickel oxides (78% of the control). The high toxicity of nanoparticles with respect to bacteria was recorded by researchers for other metals as well [21][22][23][24][25][26][27] .…”

“…Numerous researches are devoted to estimation of nanoparticle environmental impact. The influence of nanopowders on animals [3][4][5][6][7] , plants [8][9][10][11][12][13][14][15][16] , bacteria [17][18][19][20][21][22][23][24][25] , ferment activity [26][27][28][29] has been studied. The environmental impact of nanopowders, including the impact on soil, should be studied in more details due to the inconsistency of estimations: some authors evidence safety of environmental pollution with nanoparticles, and the others point to significant risks.…”