Antibacterial activity of Solanum elaeagnifolium Cav. stem and leaf extract against human pathogenic bacteria

Balavivekananthan, S; Xavier, T. Francis; Kumar, Sanjeet; Sabitha, R.

doi:10.5958/0974-360x.2021.00238.9

Cited by 4 publications

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“…Our results are consistent with those of Bouslamti and co-authors, who discovered the antibacterial activity of hydroethanolic and hydroacetonic extracts against bacteria including E. coli K12, S. aureus ATCC 6633, B. subtilis DSM 6333, and Proteus mirabilis ATCC 29,906 [13]. Extracts of the genus Solanum demonstrated good antibacterial effects against some clinically important pathogenic bacteria, including Staphylococcus lentus and Staphylococcus haemolyticus [40]. The chemical composition of S. elaeagnifolium leaf and fruit extracts is rich in secondary metabolites such as quercetin, chlorogenic acid, and apigenin [14], which contribute to its antimicrobial activity.…”

Section: S Aureus E Coli B Subtilis P Mirabilis C Albicans Sfsupporting

confidence: 92%

Solanum elaeagnifolium Var. Obtusifolium (Dunal) Dunal: Antioxidant, Antibacterial, and Antifungal Activities of Polyphenol-Rich Extracts Chemically Characterized by Use of In Vitro and In Silico Approaches

et al. 2022

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The present work was designed to study the chemical composition and the antioxidant and antimicrobial properties of fruits (SFr) and leaf (SF) extracts from Solanum elaeagnifolium var. obtusifolium (Dunal) Dunal (S. elaeagnifolium). The chemical composition was determined using HPLC-DAD analysis. Colorimetric methods were used to determine polyphenols and flavonoids. Antioxidant capacity was assessed with DPPH, TAC, and FRAP assays. Antimicrobial activity was assessed using disk diffusion and microdilution assays against two Gram (+) bacteria (Staphylococcus aureus ATCC-6633 and Bacillus subtilis DSM-6333) and two Gram (-) bacteria (Escherichia coli K-12 and Proteus mirabilis ATCC-29906), while the antifungal effect was tested vs. Candida albicans ATCC-1023. By use of in silico studies, the antioxidant and antimicrobial properties of the studied extracts were also investigated. HPLC analysis showed that both fruits and leaf extracts from S. elaeagnifolium were rich in luteolin, quercetin, gallic acid, and naringenin. Both SFr and SF generated good antioxidant activity, with IC50 values of 35.15 ± 6.09 μg/mL and 132.46 ± 11.73 μg/mL, respectively. The EC50 of SFr and SF was 35.15 ± 6.09 μg/mL and 132.46 ± 11.73 μg/mL, respectively. SFr and SF also showed a good total antioxidant capacity of 939.66 ± 5.01 μg AAE/and 890.1 ± 7.76 μg AAE/g, respectively. SFr had important antibacterial activity vs. all tested strains—most notably B. subtilis DSM-6333 and E. coli, with MICs values of 2.5 ± 0.00 mg/mL and 2.50 ± 0.00 mg/mL, respectively. SFr demonstrated potent antifungal activity against C. albicans, with an inhibition diameter of 9.00 ± 0.50 mm and an MIC of 0.31 ± 0.00 mg/mL. The in silico approach showed that all compounds detected in SFr and SF had high activity (between −5.368 and 8.416 kcal/mol) against the receptors studied, including NADPH oxidase, human acetylcholinesterase, and beta-ketoacyl-[acyl carrier protein] synthase.

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Section: S Aureus E Coli B Subtilis P Mirabilis C Albicans Sfsupporting

confidence: 92%

Solanum elaeagnifolium Var. Obtusifolium (Dunal) Dunal: Antioxidant, Antibacterial, and Antifungal Activities of Polyphenol-Rich Extracts Chemically Characterized by Use of In Vitro and In Silico Approaches

et al. 2022

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“…To our knowledge, no detailed information is available on the antimicrobial activities, especially the antifungal properties, of S. elaeagnifolium in the literature. Our findings are consistent with those of [23], which indicated that HAE and HEE of S. elaeagnifolium Cav. show significant antibacterial activity against some selected human pathogenic bacteria, such as Escherichia coli, Staphylococcus aureus, Klebsiella oxytoca, Bacillus cereus, Serratia marcescens, Klebsiella pneumonia, Enterobacter amnigenus, Staphylococcus lentus, Staphylococcus haemolyticus, and Brevibacterium paucivorans, and also with the study of [42], which demonstrates that S. elaeagnifolium extract does not show any activity against C. albicans, but our results are in contradiction with the same study for S. aureus results.…”

Section: Antimicrobial Activity Of S Elaeagnifolium Hydro-ethanolic E...supporting

confidence: 91%

“…The fruits of S. elaeagnifolium showed hepatoprotective [21], anti-inflammatory, and analgesic activities [22]. Extracts from the stem and leaves have exhibited antimicrobial effect against pathogenic strains [23].…”

Section: Introductionmentioning

confidence: 99%

Total Polyphenols Content, Antioxidant and Antimicrobial Activities of Leaves of Solanum elaeagnifolium Cav. from Morocco

et al. 2022

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Solanum elaeagnifolium is among the invasive plants of Morocco; studies on its chemical composition and biological activities are few in number in Morocco. S. elaeagnifolium has shown molluscicidal and nematicidal and cancer-inhibitory effects, anti-inflammatory, analgesic activity, and antibacterial activity. The objective of this research is to improve this plant and assess its antibacterial and antioxidant properties as well as its total polyphenolic content (TPC) and total flavonoid content (TFC). The Folin-Ciocalteu method and the aluminium-trichloride method were used to determine TPC and TFC in hydro-ethanolic (HEE) and hydro-acetonic (HAE) leaf extract. Three assays were performed to determine the antioxidant activity: the DPPH test (radical 2,2’-diphenyl-1-picrylhydrazyl), the FRAP test (Ferric Reducing Antioxidant Power), and the TAC test. Disk diffusion and microdilution were used to test antibacterial activity against four pathogenic bacteria and Candida albicans. The hydro-ethanolic extract 2.54 ± 0.4 mg EAG/g has a greater polyphenol concentration than the hydro-acetonic extract 1.58 ± 0.03 mg EAG/g. Although the flavonoid content of the hydro-acetonic extract (0.067 ± 0.001 mg EQ/g) is larger than that of the hydro-ethanolic extract (0.012 ± 0.001 mg EQ/g), the flavonoid content of the hydro-ethanolic extract (0.012 ± 0.001 mg EQ/g). The DPPH values were IC-50 = 0.081 ± 0.004 mg/mL for hydro-ethanoic extract and 0.198 ± 0.019 mg/mL for hydro-acetonic extract, both extracts superior to BHT (0.122 ± 0.021 g/mL). While the FRAP assay showed a low iron-reducing power values for both extracts compared to BHT), the overall antioxidant activity of the two extracts was found to be considerable. The overall antioxidant activity of the hydro-ethanolic extract was 8.95 ± 0.42 mg EAA/g, whereas the total antioxidant activity of the hydro-acetonic extract was 6.44 ± 0.61 mg EAA/g. In comparison with the antibiotic Erythromycin, HAE and HEE from S. elaeagnifolium leaves demonstrated significant antibacterial action. HAE had the best inhibitory efficacy against Bacillus subtilis DSM 6333, with an inhibition diameter of 10.5 ± 0.50 mm and a MIC of 7.5 ± 0.00 mg/mL, as well as against Proteus mirabilis ATCC 29906, with an inhibitory diameter of 8.25 ± 0.75 mm and a MIC of 15 ± 0.00 mg/mL.

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“…The plant has also been found to contain compounds that appear to limit the growth of cancer cell lines, paving the way for the exploitation of these compounds as anticancer agents (Hernández et al 2017). Leaf extracts are considered effective for the containment of various human pathogenic bacteria (Balavivekananthan et al 2021).…”

Section: Importancementioning

confidence: 99%

Biology of Invasive Plants 5. Solanum elaeagnifolium Cav.

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et al. 2023

Invasive plant sci. manag.

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The family Solanaceae lists about 1,400 species worldwide, of which 143 are considered weeds (Sheppard et al. 2006). The genus Solanum is the most numerous of the family Solanaceae. Solanum elaeagnifolium Cav. belongs to the clade Leptostemonum, commonly known as the “spiny solanum” clade. Solanum elaeagnifolium is native to northern Mexico and the American Southwest. A revision for the S. elaeagnifolium clade and analytic phytokeys are provided by Knapp et al. (2017). The silvery color of its leaves and their resemblance to the leaves of the olive tree (Elaeagnus) were the reasons for naming the species elaeagnifolium (Heap and Carter 1999). Nowadays, it is commonly known as silverleaf nightshade (Boyd et al. 1984). According to Krigas et al. (2021), in northern Greece S. elaeagnifolium is also called “Lernaean Hydra,” due to its intense regrowth after herbicide treatment. Solanum elaeagnifolium is known in South Africa as silverleaf bitter apple or Satansbos (Satan’s bush), indicating how harmful it is to the country (Wilson et al. 2013). In America and other parts of the world, it has received various names over the years, such as white horsenettle, bullnettle, tomatillo, meloncillo, and trompillo (Davis et al. 1945; Kwong et al. 2006). In Algeria, farmers call it echouka, which means thorn, because of the multiple spines on the stem (Adjim and Kazi Tani 2018). In South Korea, it received the name Eun-bit-kka-ma-jung, which is a combination of its silvery coloration and a common plant in the country (Hong et al. 2014).

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Antibacterial activity of Solanum elaeagnifolium Cav. stem and leaf extract against human pathogenic bacteria

Cited by 4 publications

References 0 publications

Solanum elaeagnifolium Var. Obtusifolium (Dunal) Dunal: Antioxidant, Antibacterial, and Antifungal Activities of Polyphenol-Rich Extracts Chemically Characterized by Use of In Vitro and In Silico Approaches

Solanum elaeagnifolium Var. Obtusifolium (Dunal) Dunal: Antioxidant, Antibacterial, and Antifungal Activities of Polyphenol-Rich Extracts Chemically Characterized by Use of In Vitro and In Silico Approaches

Total Polyphenols Content, Antioxidant and Antimicrobial Activities of Leaves of Solanum elaeagnifolium Cav. from Morocco

Biology of Invasive Plants 5. Solanum elaeagnifolium Cav.

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