Antibacterial activity of the Calendula officinalis L. essential oil on Escherichia coli

Abstract

In developing countries, the risk of getting sick from eating food contaminated with Escherichia coli is very high. As a consequence of the multidrug resistance of this bacterium, a therapeutic alternative has been sought in the plant kingdom. The Objective of this research was to evaluate the antibacterial effect of pot marigold (Calendula officinalis) essential oil (EO) on the growth of E. coli. Design/Methodology/Approach: The antibacterial activity was determined using a Kirby-Bauer disk diffusion susceptibility test. A 90 to 60% dilution of EO generated 24 to 22 mm halos. The EA was subjected to a GC/MS analysis. The results showed that cadinene (53.8%) was the main constituent, followed by germacrene (22.5%). The minimum inhibitory concentration was 7 μg mL-1. Findings/Conclusions: C. officinalis EO can be considered as an option in the treatment against this enterobacteria.

Utilization of nanotechnology and experimental design in the development and optimization of a posaconazole‒calendula oil nanoemulgel for the treatment of mouth disorders

“…In addition, the group treated with the optimal formulation containing oleic acid instead of CO as an oil phase had an ulcer index of 2 ± 1, which indicated the presence of a spot ulceration of less than 1 mm. Such findings also confirmed the importance of CO in treating gingival ulcers, which could be explained by the previously mentioned conditions (Ruíz-Posadas et al, 2023).…”

“…The anticancer, anti-inflammatory, and antibacterial properties of this class of drugs have also been described by Salazar-Gómez et al ( 2020) (Salazar-Gómez et al, 2020). Major components of an essential oil can be responsible for its antibacterial action, even though the effect is dependent on the composition of metabolites in the oil (Ruíz-Posadas et al, 2023).…”