Antibacterial Activity of Zinc Oxide Nanoparticles Synthesized by Solochemical Process

Abstract

ZnO-NPs can be obtained through various methods, resulting in nanoparticles with different size and morphology, which directly influences their antimicrobial potential. The objective of this work was to evaluate the antibacterial activity of ZnO-NPs obtained by a solochemical process against important human foodborne pathogens: Staphylococcus aureus, Salmonella Typhimurium, Bacillus cereus and Pseudomonas aeruginosa. ZnO-NPs were identified as nanorods with the length between 90.1 and 100 nm (10.5 % frequency), the diameter between 80.1 and 90 nm (21 % frequency), and wurtzite type crystalline structure. The Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) were equal to 0.05 mg mL-1 and 0.5 mg mL-1 for S. aureus and S. Typhimurium, respectively, lower than previous results related in the literature. ZnO-NPs produced by solochemical method had a superior antibacterial activity. For instance, they can be incorporated in packaging materials for increasing microbial safety and food shelf-life by inhibiting bacterial growth.

Structural and biochemical modifications of model and native membranes of human immune cells in response to the action of zinc oxide nanoparticles

“…Effective antibacterial action also requires high doses of these nanomaterials. Many studies indicate that the lowest concentration of ZnO nanoparticle suspension, which caused an over 99.9% reduction in initial inoculum (MBC) ranges from tens to even 5000 mg/L depending on the bacterial serotype and the method of nanoparticle synthesis (Alekish, Ismail, Albiss, & Nawasrah, 2018; Hoseinzadeh, Alikhani, Samarghandi, & Shirzad‐Siboni, 2013; Raj, Lawrence, Jalees, & Lawrence, 2015; Souza, Haberbeck, Riella, Ribeiro, & Carciofi, 2019). Despite high contact concentrations, the concentration of ZnO‐NPs in the body will be lower, and therefore, the amounts used for the presented research were much lower than usually used in industry.…”

Advances of Non-Iron Metal Nanoparticles in Biomedicine

“…On the other hand, the Gram-positive organism (Bacillus cereus) was unaffected by the action of NPs. The minimum inhibitory concentration (MIC) was found to be 0.05 mg/mL and the minimum bactericidal concentration (MBC) was 0.5 mg/mL for both S. aureus and Salmonella typhimurium [44].…”

Enhancement of Antibacterial and Mechanical Features of Glass Ionomer Restoration by Adding ZnO Nanoparticles Prepared by PLAL: In Vitro Study

“…xpert high score plus program. [20]. Table 2 calculated the mean grain size and lattice strain of the ZnONPs.…”