Antibacterial and Anti-Biofilm Biosynthesised Silver and Gold Nanoparticles for Medical Applications: Mechanism of Action, Toxicity and Current Status

Abdalla, Sundos Suleman Ismail; Katas, Haliza; Azmi, Fazren; Fauzi, Mh Busra

doi:10.2174/1567201817666191227094334

Cited by 59 publications

(38 citation statements)

References 91 publications

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“…Still, the synthesis steps present a potentially toxic effect on the environment [ 15 , 16 ]. Green biosynthesis, as a biological method suitable to obtain NPs, is easy to perform, less expensive, environmentally friendly, and very vast in the existence and access of starting material, namely organism material, because of the enormous plant kingdom metabolites/organisms strains [ 17 , 18 , 19 , 20 , 21 , 22 , 23 ]. Green synthesis of metal-based NPs could use fungi, bacteria, yeast, algae, and plant extracts.…”

Section: Introductionmentioning

confidence: 99%

Green Synthesis, Characterization, and Antibacterial Properties of Silver Nanoparticles Obtained by Using Diverse Varieties of Cannabis sativa Leaf Extracts

et al. 2021

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Cannabis sativa L. (hemp) is a plant used in the textile industry and green building material industry, as well as for the phytoremediation of soil, medical treatments, and supplementary food products. The synergistic effect of terpenes, flavonoids, and cannabinoids in hemp extracts may mediate the biogenic synthesis of metal nanoparticles. In this study, the chemical composition of aqueous leaf extracts of three varieties of Romanian hemp (two monoecious, and one dioecious) have been determined by Fourier-Transformed Infrared spectroscopy (FT-IR), high-performance liquid chromatography, and mass spectrometry (UHPLC-DAD-MS). Then, their capability to mediate the green synthesis of silver nanoparticles (AgNPs) and their pottential antibacterial applications were evaluated. The average antioxidant capacity of the extracts had 18.4 ± 3.9% inhibition determined by 2,2-diphenyl-1-picrylhydrazyl (DPPH•) and 78.2 ± 4.1% determined by 2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS™) assays. The total polyphenolic content of the extracts was 1642 ± 32 mg gallic acid equivalent (GAE) L−1. After this, these extracts were reacted with an aqueous solution of AgNO3 resulting in AgNPs, which were characterized by UV−VIS spectroscopy, FT-IR, scanning electron microscopy (SEM-EDX), and dynamic light scattering (DLS). The results demonstrated obtaining spherical, stable AgNPs with a diameter of less than 69 nm and an absorbance peak at 435 nm. The mixture of extracts and AgNPs showed a superior antioxidant capacity of 2.3 ± 0.4% inhibition determined by the DPPH• assay, 88.5 ± 0.9% inhibition as determined by the ABTS•+ assay, and a good antibacterial activity against several human pathogens: Escherichia coli, Klebsiella pneumoniae, Pseudomonas fluorescens, and Staphylococcus aureus.

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Section: Introductionmentioning

confidence: 99%

Green Synthesis, Characterization, and Antibacterial Properties of Silver Nanoparticles Obtained by Using Diverse Varieties of Cannabis sativa Leaf Extracts

et al. 2021

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“…Antibacterial coatings of biocompatible polymers based on metal nanoparticles (NPs), especially gold, silver, and copper, have great potential in preventing or reducing the accumulation of biofilms on the surface of medical devices [9,10]. In particular, especially silver nanoparticles (AgNPs) are important candidates for the role of an alternative to conventional antibiotics.…”

Section: Introductionmentioning

confidence: 99%

Surface Texturing of Polyethylene Terephthalate Induced by Excimer Laser in Silver Nanoparticle Colloids

et al. 2021

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We report on a novel technique of surface texturing of polyethylene terephthalate (PET) foil in the presence of silver nanoparticles (AgNPs). This approach provides a variable surface morphology of PET evenly decorated with AgNPs. Surface texturing occurred in silver nanoparticle colloids of different concentrations under the action of pulse excimer laser. Surface morphology of PET immobilized with AgNPs was observed by AFM and FEGSEM. Atomic concentration of silver was determined by XPS. A presented concentration-controlled procedure of surface texturing of PET in the presence of silver colloids leads to a highly nanoparticle-enriched polymer surface with a variable morphology and uniform nanoparticle distribution.

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“…Nowadays, with the rapid development of nanoscience and nanotechnology, it has proposed solutions different from traditional methods for people to diagnose, resist, and overcome various diseases. At present, metal nanoparticles have been developed, mainly silver and gold nanoparticles (AgNPs and AuNPs, respectively), which can be applied to many aspects in the medical and pharmaceutical fields, including antibacterial, antibiofilm, drug delivery systems, diagnostic tools, and Personal care products and cosmetics [12]. This article primarily summarizes the recent research progress into functionalized gold nanoparticles in mixed antibacterial and the application of gold nanoparticles in oral biology.…”

Section: Introductionmentioning

confidence: 99%

Antibacterial Properties of Functionalized Gold Nanoparticles and Their Application in Oral Biology

Huang

et al. 2020

Journal of Nanomaterials

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As bacterial resistance is becoming increasingly serious, the development of antibacterial nanomaterials is an effective method of solving this problem. Gold nanoparticles have good stability and excellent biocompatibility and are easily modified, and their antibacterial properties can be enhanced by changing their structure and size or adding ingredients. Gold nanoparticles are also excellent drug carriers that can improve the antibacterial effects of loaded antibacterial drugs. After being modified and combined with other antibacterial drugs, gold nanoparticles can also play a better antibacterial role for effective antibacterial strategies against some resistant bacteria. Gold nanoparticles have photothermal effects, and modified gold nanoparticles can be a good medium for photothermal treatments to kill bacteria. By adding functionally modified gold nanoparticles, many materials can obtain much needed antibacterial properties. Gold nanoparticles can also be combined with cations, low-temperature plasma, various surface ligands, and other potential antibacterial agents. In short, the antibacterial characteristics of functionalized gold nanoparticles demonstrate that they have considerable practical application value and provide more ideas to solve antibacterial problems. At the same time, the application of gold nanoparticles in oral biology is also increasing.

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Antibacterial and Anti-Biofilm Biosynthesised Silver and Gold Nanoparticles for Medical Applications: Mechanism of Action, Toxicity and Current Status

Cited by 59 publications

References 91 publications

Green Synthesis, Characterization, and Antibacterial Properties of Silver Nanoparticles Obtained by Using Diverse Varieties of Cannabis sativa Leaf Extracts

Green Synthesis, Characterization, and Antibacterial Properties of Silver Nanoparticles Obtained by Using Diverse Varieties of Cannabis sativa Leaf Extracts

Surface Texturing of Polyethylene Terephthalate Induced by Excimer Laser in Silver Nanoparticle Colloids

Antibacterial Properties of Functionalized Gold Nanoparticles and Their Application in Oral Biology

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