Antibacterial and anti-inflammatory effects of Jeju medicinal plants against acne-inducing bacteria

Kim, Sang Suk; Kim, Jiyoung; Lee, Nam Ho; Hyun, Chang‐Gu

doi:10.2323/jgam.54.101

Cited by 34 publications

(30 citation statements)

References 14 publications

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“…Similar to the dermatophytes, it has been rarely addressed in southern Africa with respect to medicinal plant studies. The in vitro antimicrobial and anti-inflammatory properties of medicinal plants against P. acnes have been investigated in a number of studies abroad (Chomnawang et al, 2005;Kim et al, 2007Kim et al, , 2008Tsai et al, 2010;Balakrishnan et al, 2011). Furthermore, the relevance of P. acnes has also been detailed in a review on the traditional uses, phytochemistry and pharmacology of Psidium guajava (Gutiérrez et al, 2008), yet little attention has been given to this pathogen when investigating southern African plants.…”

Section: Staggers Weed Leavesmentioning

confidence: 98%

Southern African medicinal plants used to treat skin diseases

Mabona

Vuuren

2013

South African Journal of Botany

118

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a b s t r a c tThis overview of southern African medicinal plants of dermatological relevance explores the fundamental knowledge available on the antimicrobial, anti-inflammatory, and wound healing properties of medicinal plants used to treat skin ailments. Also included is an overview undertaken on the phytochemistry and toxicity of plants used in treatments related to diseases of the skin. Some findings include the predominance of leaf material used (48%), as well as the frequent use of decoctions (35%). Dermatological skin pathogens such as Propionibacterium acnes, Microsporum canis, Trichophyton mentagrophytes and Epidermophyton floccosum are recommended for study in future antimicrobial research. Attention to these aspects should lead to new directives for commercialization and provide insight towards the understanding of some neglected plant species used for the treatment of skin diseases.

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Section: Staggers Weed Leavesmentioning

confidence: 98%

Southern African medicinal plants used to treat skin diseases

Mabona

Vuuren

2013

South African Journal of Botany

118

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“…Another well-known plant is Angelica anomala which had strong inhibitory effects against P. acnes and S. epidermidis with MIC values of 15.6 μ g/mL and 126 μ g/mL, respectively. Mollugo pentaphylla , Matteuccia orientalis, and Orixa japonica also inhibited the growth of both pathogens, along with the reduction in P. acnes induced secretion of IL-8 and TNF- α in THP-1 cells [63]. Caesalpinia sappan and Intsia palembanica were noted as potent antiacne plants based on their antibacterial (MIC 0.13 mg/mL; MBC 0.25 mg/mL), lipase inhibitory, and antioxidative properties [64].…”

Section: Plants Having Antiacne Potentialmentioning

confidence: 99%

New Perspectives on Antiacne Plant Drugs: Contribution to Modern Therapeutics

Sinha

Srivastava

Mishra

et al. 2014

BioMed Research International

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Acne is a common but serious skin disease, which affects approximately 80% adolescents and young adults in 11–30 age group. 42.5% of men and 50.9% of women continue to suffer from this disease into their twenties. Bacterial resistance is now at the alarming stage due to the irrational use of antibiotics. Hence, search for new lead molecule/bioactive and rational delivery of the existing drug (for better therapeutic effect) to the site of action is the need of the hour. Plants and plant-derived products have been an integral part of health care system since time immemorial. Therefore, plants that are currently used for the treatment of acne and those with a high potential are summarized in the present review. Most active plant extracts, namely, P. granatum, M. alba, A. anomala, and M. aquifolium exhibit minimum inhibitory concentration (MIC) in the range of 4–50 µg/mL against P. acnes, while aromatic oils of C. obovoides, C. natsudaidai, C. japonica, and C. nardus possess MICs 0.005–0.6 μL/mL and phytomolecules such as rhodomyrtone, pulsaquinone, hydropulsaquinone, honokiol, magnolol, xanthohumol lupulones, chebulagic acid and rhinacanthin-C show MIC in the range of 0.5–12.5 μg/mL. Novel drug delivery strategies of important plant leads in the treatment of acne have also been discussed.

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“…Triterpenoidal saponins such as kalopanax saponins are the main compounds in the stem bark of K. pictus Sano et al, 1991) and these compounds have beneficial properties such as anti-diabetic and anti-mutagenic activities Park et al, 1998). Lirodendrin and syringin, compounds having anti-tumor and pain-relieving activities, have also been isolated from the stem bark of K. pictus (Kim et al, 2007;Sano et al, 1991;Choi et al, 2002). Recently, various ligans and steroids such as stigmastane sterols containing hydroxyl groups were isolated from K. pictus (Hong et al, 2006;Lyu et al, 2009).…”

Section: Discussionmentioning

confidence: 99%

Discrimination of Kalopanax pictus from its varieties and other ‘Kalopanacis Cortex’ plants by multiplex polymerase chain reaction (PCR)

Doh

Yang

et al. 2011

Genes Genom

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Kalopanacis Cortex' (KC) is an important medicinal material prescribed in Korea for the treatment of various ailments such as paralysis, arthritis, and rheumatism. In Korea, KC is defined as the dried stem bark of Kalopanax pictus. However, the stem barks of Zanthoxylum ailanthoides and Erythrina plants such as E. variegata have also been described as KC and prescribed for the same diseases. Since the pharmacological activities and contents of compounds isolated from the stem barks of these KC plants are obviously different, KC from K. pictus should be clearly discriminated from other stem bark in the best interest of public health. This study sequenced the internal transcribed spacers (ITS) of 52 samples of the KC or KC plants collected from Korea, China, and Vietnam. On the basis of different nucleotide sequences of specific ITS regions among the KC plants, the primer set KP F2/KC R1 was designed to amplify a 398-bp DNA marker for discriminating K. pictus from its varieties and from other KC plants. This primer set, along with the primer sets ZR F1/ZR R4, KP F1/EV R2, and KPF1/KC R1, was successfully amplified with the DNA markers of the Z. ailanthoides, E. variegata, and K. pictus taxa, respectively. The multiplex polymerase chain reaction method developed here not only discriminates the stem bark of K. pictus from stem barks of other KC plants but also identifies KC plants that supply KC in a single process.

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Antibacterial and anti-inflammatory effects of Jeju medicinal plants against acne-inducing bacteria

Cited by 34 publications

References 14 publications

Southern African medicinal plants used to treat skin diseases

Southern African medicinal plants used to treat skin diseases

New Perspectives on Antiacne Plant Drugs: Contribution to Modern Therapeutics

Discrimination of Kalopanax pictus from its varieties and other ‘Kalopanacis Cortex’ plants by multiplex polymerase chain reaction (PCR)

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