Antibacterial and Anticancer Activities of Turmeric and its Active Ingredient Curcumin, and Mechanism of Action

Singh, Dev Bukhsh; Maurya, Ajay Kumar; Rai, Dipti

doi:10.2174/9781681087511119010006

Cited by 6 publications

(6 citation statements)

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“…Fresh turmeric contains zingiberene, while the most significant curcuminoid presented in turmeric is curcumin. Previous literature has reported that turmeric has an antimicrobial (antibacterial and antifungal) effect [ 49 , 140 , 141 , 142 ]. Curcumin is known for its inhibitory action on microorganisms such as E. coli, S. aureus, Salmonella typhimurium , and Pseudomonas aeruginosa [ 141 , 143 ].…”

Section: Antimicrobial Agentmentioning

confidence: 99%

“…Previous literature has reported that turmeric has an antimicrobial (antibacterial and antifungal) effect [49,[140][141][142]. Curcumin is known for its inhibitory action on microorganisms such as E. coli, S. aureus, Salmonella typhimurium, and Pseudomonas aeruginosa [141,143]. In numerous literature works, turmeric's extracts have been shown to have strong antioxidant properties.…”

Section: Turmericmentioning

confidence: 99%

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Antioxidant, Antimicrobial and Antiviral Properties of Herbal Materials

et al. 2020

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Recently, increasing public concern about hygiene has been driving many studies to investigate antimicrobial and antiviral agents. However, the use of any antimicrobial agents must be limited due to their possible toxic or harmful effects. In recent years, due to previous antibiotics’ lesser side effects, the use of herbal materials instead of synthetic or chemical drugs is increasing. Herbal materials are found in medicines. Herbs can be used in the form of plant extracts or as their active components. Furthermore, most of the world’s populations used herbal materials due to their strong antimicrobial properties and primary healthcare benefits. For example, herbs are an excellent material to replace nanosilver as an antibiotic and antiviral agent. The use of nanosilver involves an ROS-mediated mechanism that might lead to oxidative stress-related cancer, cytotoxicity, and heart diseases. Oxidative stress further leads to increased ROS production and also delays the cellular processes involved in wound healing. Therefore, existing antibiotic drugs can be replaced with biomaterials such as herbal medicine with high antimicrobial, antiviral, and antioxidant activity. This review paper highlights the antibacterial, antiviral, and radical scavenger (antioxidant) properties of herbal materials. Antimicrobial activity, radical scavenger ability, the potential for antimicrobial, antiviral, and anticancer agents, and efficacy in eliminating bacteria and viruses and scavenging free radicals in herbal materials are discussed in this review. The presented herbal antimicrobial agents in this review include clove, portulaca, tribulus, eryngium, cinnamon, turmeric, ginger, thyme, pennyroyal, mint, fennel, chamomile, burdock, eucalyptus, primrose, lemon balm, mallow, and garlic, which are all summarized.

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Section: Antimicrobial Agentmentioning

confidence: 99%

Section: Turmericmentioning

confidence: 99%

Antioxidant, Antimicrobial and Antiviral Properties of Herbal Materials

et al. 2020

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“…Because of its effects on key cell cycle signaling pathways and its success in animal model systems, curcumin has been recognized as a multifaceted weapon in the fight against cancer. 33 deadly cancer. Natural phytochemicals such as curcumin could connect to these new targets and synergize with chemotherapy.…”

Section: Review For Anticancer Activity Of Turmericmentioning

confidence: 99%

Ethnopharmacological review of turmeric for anticancer activity

Nerkar¹,

Nagarkar²,

Badar³

2023

CTPPC

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These reviews suggest that in the Indian subcontinent, turmeric (Curcuma longa Linn) is widely grown and consumed as a spice. Traditional medicine has used turmeric to treat a variety of ailments, such as diabetes, liver disease, and cough. Many studies have been conducted over the past decades to determine the pharmacological effects of turmeric and its derivatives. The main chemical component of turmeric, curcumin, has been shown to have pharmacological properties including anti-inflammatory, antioxidant, anti-mutagenic, antidiabetic, and antibacterial properties., protect liver, expectorant and anti-cancer. Turmeric, also known as Curcuma longa L. (root and rhizome), is a plant of high medicinal and commercial value, mainly used as a spice and food supplement around the world. The three curcuminoids - curcumin (diferuloylmethane, the main ingredient that gives turmeric its yellow color), demethoxycurcumin, and bisdemethoxycurcumin - are the main active ingredients of turmeric. Volatile oils (zingiberene, atlantone, tomerol, etc.) also have pharmacological effects. In addition, turmeric contains proteins, resins and carbohydrates. Turmeric is a powerful antioxidant and has significant anti-inflammatory properties. Turmeric's anti-inflammatory properties may be directly related to its anti-cancer properties. In this review, the anticancer properties of Turmeric have been reviewed.

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“…Turmeric (Curcumin) is one of the natural medicines historically utilized. It has both antibacterial and antifungal activity (Gitika et al, 2019;Singh et al, 2019). It also shows strong anti-cancer potential (Singh et al, 2019).…”

Section: A Natural Extractsmentioning

confidence: 99%

Antibacterial/Antiviral Face Masks: Processing, Characteristics, Challenges, and Sustainability

Hoque,

Sarker,

Arif

et al. 2023

MIJST

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The face mask has become a part of our daily life after the emergence of SAR-CoV-2, commonly known as the novel coronavirus 2019 or, COVID-19 all over the world. On a day-to-day basis, previously the face mask has been used to filter airborne particles entering the body and affecting the respiratory system, especially by individuals in pollution-prone areas. But as the pathogens having severe acute respiratory disease-causing abilities emerge with the potential to create a pandemic, the necessity of virus/bacteria killing ability along with the filtration efficiency of the face mask has come into account. Existing ordinary face masks have filtration capacity only. Sometimes it cannot restrict particles and pathogens of nano or even micro-scale. Moreover, when it is disposed of after use, it can be a potential source of pathogen transmission. Therefore, the development of antiviral/antibacterial face masks is the need of the hour. This article focuses on the advancement of face mask processing methods, existing and promising antibacterial/antiviral agents, socio-economic sustainability, and challenges in achieving the goal of a green environment. Besides, various characteristics of the face mask like swelling and degradation properties, morphologies (SEM, FESEM), mechanical strength, antioxidant property, and antimicrobial activity are also revealed. Lastly, some future perspectives and directives are accordingly discussed with the hope that the grim of any future pandemic should not shroud us and make the world stalled again.

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Antibacterial and Anticancer Activities of Turmeric and its Active Ingredient Curcumin, and Mechanism of Action

Cited by 6 publications

References 0 publications

Antioxidant, Antimicrobial and Antiviral Properties of Herbal Materials

Antioxidant, Antimicrobial and Antiviral Properties of Herbal Materials

Ethnopharmacological review of turmeric for anticancer activity

Antibacterial/Antiviral Face Masks: Processing, Characteristics, Challenges, and Sustainability

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