2016
DOI: 10.1080/22311866.2016.1184990
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Antibacterial and Anticancer Properties ofDolichos kilimandscharicus(Fabaceae)

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Cited by 4 publications
(3 citation statements)
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“…The chromone derivative, acthaside isolated from dried bark of Acacia ataxacantha exhibited antibacterial activity against both Gram-positive and Gram-negative microorganisms, though Gram-positive bacteria showed a greater susceptibility overall [52]. In Dolichos kilimandscharicus , saponins were found to inhibit Gram-positive bacteria [53]. Gram-positive bacteria also succumbed to the CW-destabilizing effects of terpenoids and flavonoids in extracts of Cassia abbreviata, Senna didymobotrya , Parkinsonia aculeata [54].…”
Section: Discussionmentioning
confidence: 99%
“…The chromone derivative, acthaside isolated from dried bark of Acacia ataxacantha exhibited antibacterial activity against both Gram-positive and Gram-negative microorganisms, though Gram-positive bacteria showed a greater susceptibility overall [52]. In Dolichos kilimandscharicus , saponins were found to inhibit Gram-positive bacteria [53]. Gram-positive bacteria also succumbed to the CW-destabilizing effects of terpenoids and flavonoids in extracts of Cassia abbreviata, Senna didymobotrya , Parkinsonia aculeata [54].…”
Section: Discussionmentioning
confidence: 99%
“…Root and tuber of D. kilimandscharicus are known for antifungal and ant-molluscicidal properties attributed by saponins [53,54]. In this study, D. kilimandscharicus tuber extracts revealed the highest toxicity with LC 50 values of 7.937 × 10 −4 mg/mL, 3.5192 × 10 −3 mg/mL, 1.468 × 10 −2 mg/ mL, and 7.242 × 10 −2 mg/mL for pet ether, water, ethyl acetate, and methanolic extracts, respectively (Table 2).…”
Section: Determination Of Antibacterial Activitymentioning
confidence: 99%
“…The chromone derivative, acthaside isolated from dried bark of Acacia ataxacantha displayed antibacterial activity against both Gram-positive and Gram-negative microorganisms, though Grampositive bacteria showed a greater susceptibility overall(Amoussa, Bourjot, Lagnika, Vonthron-Sénécheau, & Sanni, 2016). In Dolichos kilimandscharicus, saponins were found to hinder Gram-positive bacteria(Shava et al, 2016).Gram-positive bacteria likewise surrendered to the cell wall destabilizing effects of terpenoids and flavonoids in extracts of Cassia abbreviata, Senna didymobotrya and Parkinsonia aculeata(Madureira, Ramalhete, Mulhovo, Duarte, & Ferreira, 2012) polyphenolic extracts from Vicia faba, Cajanus indica(Chanda, Dudhatra, & Kaneria, 2010) Arachis hypogea(Tamura, Ozawa, Tanaka, Arai, & Mura, 2016) and other legume species rich in isoflavonoids (Araya-Cloutier, Den Besten, Aisyah, Gruppen, & Vincken, 2017) had intense antibacterial activity against Gram-positive bacteria. Despite the fact, that Fabaceae species possess phytochemical diversity that may be synergistically damaging the cell wall, flavonoids could be one of the primary phytochemicals responsible as they form complexes with soluble proteins on bacterial cell walls(Yahaya & Idris, 2017).…”
mentioning
confidence: 99%