2018
DOI: 10.4038/cjs.v47i3.7533
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Antibacterial, antifungal, antioxidant, brine shrimp lethality and polyphenolic content of <i>Holarrhena</i> <i>mitis</i> (Vahl) R.Br. ex Roem. & Schult

Abstract: Holarrhena mitis (Vahl) R.Br. ex Roem. & Schult. which is an endemic plant growing mainly in the dry regions of the low-country has been used in the treatment of dysentery in Ayurvedic medicine. During the present study, we tested antibacterial, antifungal, antioxidant activities and brine shrimp lethality, as well as the total phenolic content of the dichloromethane, ethyl acetate and methanol extracts of the bark and leaves of H. mitis. The methanol extract of bark produced a measurable zone of inhibition ag… Show more

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Cited by 3 publications
(2 citation statements)
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“…In our previous study, several bioactivities in different sequential extracts of bark and leaves of H. mitis such as significant antifungal activity against Candida sp. which was very close to that of the positive control ketoconazole, moderate antibacterial activity against Staphylococcus aureus (ATCC 29213) and moderate antioxidant activity were observed and have directed for further studies on isolation and identification of the corresponding active compounds (Wickramasingha et al, 2018).…”
Section: Resultssupporting
confidence: 66%
See 1 more Smart Citation
“…In our previous study, several bioactivities in different sequential extracts of bark and leaves of H. mitis such as significant antifungal activity against Candida sp. which was very close to that of the positive control ketoconazole, moderate antibacterial activity against Staphylococcus aureus (ATCC 29213) and moderate antioxidant activity were observed and have directed for further studies on isolation and identification of the corresponding active compounds (Wickramasingha et al, 2018).…”
Section: Resultssupporting
confidence: 66%
“…Its bark is used in traditional medicine for the treatment of dysentery. The antibacterial, antifungal, antioxidant activities and brine shrimp lethality of sequential extracts of bark and leaf extracts of H. mitis were previously reported (Wickramasingha et al, 2018).…”
Section: Introductionmentioning
confidence: 94%