Antibacterial Applications of Anatase TiO&lt;SUB&gt;2&lt;/SUB&gt; Nanoparticle

Alhadrami, Hani A.; Baqasi, Aisha; Iqbal, Javed; Shoudri, Raniyah A.M; Ashshi, Ahmad Mohammad; Azhar, Esam I.; Al-Hazmi, Faten; Al‐Ghamdi, Ahmed A.; Wageh, S.

doi:10.12691/ajn-5-1-5

Cited by 16 publications

(5 citation statements)

References 26 publications

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“…These compounds kill cells by inactivating germ cell and DNA enzymes as well as by removing fluids from bacterial cells. Other uses of these compounds include treating and diagnosing cancer [ 68 , 69 , 70 ] . Navvabi et al (2019) recently investigated the in vitro and in viovo protoscolicidal effects of Echinometra mathaei (sea urchin gonad) extract alone or combined with TiO2 NPs.…”

Section: Discussionmentioning

confidence: 99%

High Potency of Organic and Inorganic Nanoparticles to Treat Cystic Echinococcosis: An Evidence-Based Review

et al. 2020

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Since there is no potential, effective vaccine available, treatment is the only controlling option against hydatid cyst or cystic echinococcosis (CE). This study was designed to systematically review the in vitro, in vivo, and ex vivo effects of nanoparticles against hydatid cyst. The study was carried out based on the 06- PRISMA guideline and registered in the CAMARADES-NC3Rs Preclinical Systematic Review and Meta-analysis Facility (SyRF) database. The search was performed in five English databases, including Scopus, PubMed, Web of Science, EMBASE, and Google Scholar without time limitation for publications around the world about the protoscolicdal effects of all the organic and inorganic nanoparticles without date limitation in order to identify all the published articles (in vitro, in vivo, and ex vivo). The searched words and terms were: “nanoparticles”, “hydatid cyst”, “protoscoleces”, “cystic echinococcosis”, “metal nanoparticles”, “organic nanoparticles”, “inorganic nanoparticles, “in vitro”, ex vivo”, “in vivo”. Out of 925 papers, 29 papers including 15 in vitro (51.7%), 6 in vivo (20.7%), ex vivo 2 (6.9%), and 6 in vitro/in vivo (20.7%) up to 2020 met the inclusion criteria for discussion in this systematic review. The results demonstrated the most widely used nanoparticles in the studies were metal nanoparticles such as selenium, silver, gold, zinc, copper, iron nanoparticles (n = 8, 28.6%), and metal oxide nanoparticles such as zinc oxide, titanium dioxide, cerium oxide, zirconium dioxide, and silicon dioxide (n = 8, 28.6%), followed by polymeric nanoparticles such as chitosan and chitosan-based nanoparticles (n = 7, 25.0%). The results of this review showed the high efficacy of a wide range of organic and inorganic NPs against CE, indicating that nanoparticles could be considered as an alternative and complementary resource for CE treatment. The results demonstrated that the most widely used nanoparticles for hydatid cyst treatment were metal nanoparticles and metal oxide nanoparticles, followed by polymeric nanoparticles. We found that the most compatible drugs with nanoparticles were albendazole, followed by praziquantel and flubendazole, indicating a deeper understanding about the synergistic effects of nanoparticles and the present anti-parasitic drugs for treating hydatid cysts. The important point about using these nanoparticles is their toxicity; therefore, cytotoxicity as well as acute and chronic toxicities of these nanoparticles should be considered in particular. As a limitation, in the present study, although most of the studies have been performed in vitro, more studies are needed to confirm the effect of these nanoparticles as well as their exact mechanisms in the hydatid cyst treatment, especially in animal models and clinical settings.

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Section: Discussionmentioning

confidence: 99%

High Potency of Organic and Inorganic Nanoparticles to Treat Cystic Echinococcosis: An Evidence-Based Review

et al. 2020

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“…The shift in raman peak occur due to high lattice defect such as oxygen vacancies can be created by doping of Sn ions [30,31]. ] reveals that the particles are agglomerated with size of about 8 nm 20 nm [35,36]. From the HRTEM images [Fig.…”

Section: Resultsmentioning

confidence: 99%

Investigation of metal doped mesoporous TiO2 nanostructures for environmental remediation

Santhi¹,

Harish²,

Navaneethan³

et al. 2021

Preprint

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In the recent past, metal oxides have attracted the researchers because of their applications in energy and environmental application domains. In the present work, hydrothermal technique used to prepared the Sn doped TiO2 nanoparticles and the effect of Sn concentration has been investigated. The structural, morphological, surface composition, optical and photocatalytic behavior were studied. XRD pattern revealed that doping of Sn makes easy transformation of rutile from anatase phase at lower temperature, providing tetragonal structure of rutile of TiO2. TEM analysis showed the formation of nanoparticles with spherical like morphology with good crystallinity. UV-Vis spectra, it is observed that optical absorption edge gets red shifted upon Sn doping and the band gap is found to be 2.6 eV. The photocatalytic activity of the synthesized nanoparticles has been investigated under visible light irradiation. Experimental results suggested that 0.5 wt % of Sn doped nanoparticles have shown to exhibit improved photocatalytic properties.

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“…The longer the UV radiation, the more ROS produced and can obstruct the growth of more bacteria. The size of TiO 2 nanoparticles also inhibited bacterial growth [39].…”

Section: Antibacterial Behaviourmentioning

confidence: 99%

The characteristics of TiO2 anatase from tulungagung sand as an antibacterial material

Rohmawati¹,

Istiqomah²,

Pratama³

et al. 2022

Nanosystems: Phys. Chem. Math.

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TiO 2 anatase is a material that has good photocatalytic properties. The synthesis of TiO 2 anatase from Tulungagung natural sand used the leaching method. The synthesized samples were characterized by TGA, XRD, FTIR, BET, SEM, UV-DRS and tested for antibacterial effect. In this study, the TiO 2 anatase phase was already formed and experiencing three stages of weight loss. It had stretching vibration of the OH group, had a bending mode of water Ti-OH, and Ti-O-Ti at wavenumbers 4000 to 400 cm −1 . It also had a mesoporous size, was spherical with a grain size of 58 nm and had an energy gap of 3.42 eV. TiO 2 anatase with a 600 µg/mL concentration could reduce Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa bacteria. Therefore, TiO 2 anatase has the potential in an antibacterial agent.

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Antibacterial Applications of Anatase TiO<SUB>2</SUB> Nanoparticle

Cited by 16 publications

References 26 publications

High Potency of Organic and Inorganic Nanoparticles to Treat Cystic Echinococcosis: An Evidence-Based Review

High Potency of Organic and Inorganic Nanoparticles to Treat Cystic Echinococcosis: An Evidence-Based Review

Investigation of metal doped mesoporous TiO2 nanostructures for environmental remediation

The characteristics of TiO2 anatase from tulungagung sand as an antibacterial material

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