Antibacterial Behavior of Laser-Ablated Copper Nanoparticles

Khalid, Hina; Shamaila, Shamaila; Zafar, Nosheen; Sharif, Rehana; Nazir, Jawad; Rafique, Muhammad; Ghani, Sheeba; Saba, Hussain I.

doi:10.1007/s40195-016-0450-x

Cited by 21 publications

(16 citation statements)

References 28 publications

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“…On the other hand, although previous works state a direct relationship between the bactericidal activity of copper nanoparticles and their ions' release [6], our results provide compelling evidence that ions' release is not crucial compared to other parameters, such as particle size or oxidation state. In general terms, our results are consistent with previous studies [7,34], where copper exhibits excellent antibacterial properties when tested on S. aureus.…”

Section: Analysis Of Antimicrobial Activitysupporting

confidence: 93%

“…The smaller the size, the greater the antibacterial capacity. This is consistent with previous works, and demonstrates that NPs with a large surface-to volume ratio provide more antibacterial activity [7]. On the other hand, although previous works state a direct relationship between the bactericidal activity of copper nanoparticles and their ions' release [6], our results provide compelling evidence that ions' release is not crucial compared to other parameters, such as particle size or oxidation state.…”

Section: Analysis Of Antimicrobial Activitysupporting

confidence: 93%

“…Copper, besides the fact that it is potentially effective against different bacterial pathogens [7], is a trace element. That is, an element necessary for the proper functioning of the human body in amounts less than 100 mg per day, there being recommended a daily copper intake of around 1.4 mg for an adult weighing about 70 kg [8].…”

Section: Introductionmentioning

confidence: 99%

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Fabrication and Deposition of Copper and Copper Oxide Nanoparticles by Laser Ablation in Open Air

et al. 2020

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The proximity of the "post-antibiotic era", where infections and minor injuries could be a cause of death, there are urges to seek an alternative for the cure of infectious diseases. Copper nanoparticles and their huge potential as a bactericidal agent could be a solution. In this work, Cu and Cu oxide nanoparticles were synthesized by laser ablation in open air and in argon atmosphere using 532 and 1064 nm radiation generated by nanosecond and picosecond Nd:YVO 4 lasers, respectively, to be directly deposited onto Ti substrates. Size, morphology, composition and the crystalline structure of the produced nanoparticles have been studied by the means of field emission scanning electron microscopy (FESEM), high resolution transmission electron microscopy (HRTEM), the energy dispersive spectroscopy of X-rays (EDS), selected area electron diffraction (SAED) and X-ray diffraction (XRD). The UV-VIS absorbance of the thin layer of nanoparticles was also measured, and the antibacterial capacity of the obtained deposits tested against Staphylococcus aureus. The obtained deposits consisted of porous coatings composed of copper and copper oxide nanoparticles interconnected to form chain-like aggregates. The use of the argon atmosphere contributed to reduce significantly the formation of Cu oxide species. The synthesized and deposited nanoparticles exhibited an inhibitory effect upon S. aureus.

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Section: Analysis Of Antimicrobial Activitysupporting

confidence: 93%

Section: Analysis Of Antimicrobial Activitysupporting

confidence: 93%

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Fabrication and Deposition of Copper and Copper Oxide Nanoparticles by Laser Ablation in Open Air

et al. 2020

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“…This technique also has the ability to produce NPs of controlled morphology, composition, and crystallinity. Here, chemical reduction of salts generates comparatively larger NPs as compared to that of LAL technique [24,25]. In wet chemical method, the formation of NPs has undergone by the following processes:…”

Section: Wet Chemical Methods For Nanoparticle Productionmentioning

confidence: 99%

Antibacterial Activity of Metallic Nanoparticles

Shamaila¹,

Zafar²,

Sharif³

2018

Bacterial Pathogenesis and Antibacterial Control

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Metallic nanoparticles (NPs) for medical applications have been documented since earlier times. Advancement in modern medicines results in an increase in utilization of NPs for medical purposes due to their antibacterial, antiviral, antifungal, anti-inflammatory, and antiangiogenic properties. In this chapter, three metallic NPs are studied extensively as powerful nanoweapons for the destruction of bacteria. Recent research gives evidence that metallic NPs are very effective in supporting antimicrobial activities. The chemically and laser-ablated silver, gold, and copper NPs exhibited enhanced antibacterial activity than previously reported. The antibacterial mechanism was found dose-and size-dependent and was more profound for Gram-negative bacterium as compared to Gram-positive ones. The dose calculations of minimum inhibitory concentration (MIC) with NPs have been calculated for both Gram-positive and Gram-negative bacteria. The maximum zone of inhibition by disk diffusion was also experimented against various bacteria. These NPs exhibit excellent performance physically, catalytically, and chemically. Present study will be beneficial in areas of environment, information technology, health, cosmetics, and food department. This chapter will cover the details of fabrication and antibacterial activity results of silver, gold, and copper NPs. This chapter endeavors to demonstrate the use of metallic NPs as an alternative antibacterial nanobiotics.

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“…Firstly, the observed antibacterial activity of Cu nanoparticles is highly dependent on their morphology, especially their large ratio of surface to volume, which enables them to directly interact with the outer microbial membrane of each bacterium [33]. Yin also discovered that the size and the number per unit area of the precipitates were important factors for excellent antibacterial properties [34].…”

Section: Discussionmentioning

confidence: 99%

Novel Cu-Rich Nano-Precipitates Strengthening Steel with Excellent Antibacterial Performance

Fan

et al. 2019

Metals

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In this study, a certain amount of Cu was added into tentative steel to introduce novel Cu-rich nanoprecipitates, thus enhancing strength yet without sacrificing toughness. This type of precipitates was quite different from previous ε-Cu, and was a novel type of Cu-rich nanoprecipitates, which contained more than 50% Cu. The microstructure, mechanical properties and precipitates of the steels aged at 550 °C for different holding times and were carefully examined. The microstructure of the tested steel was mainly bainite and gradually evolved into equilibrium state after aging. Mechanical properties results showed that after being aged at 550 °C for 10 min, the steel can have an excellent mechanical property combination of strength and toughness. In addition, a large amount of tiny precipitates was uniformly distributed in the matrix of the aging steels, and their size kept at nanoscale. In particular, when the steel was aged at 550 °C for 10 min, it produced the largest number of tiny precipitates of this type. This type of Cu-rich nanoprecipitates emerging from the steel aged at 550 °C for 10 min also brought about a remarkable antibacterial property. It revealed that novel Cu-rich precipitates not only have positive effects on strength and toughness, but also played an important role in antibacterial properties.

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Antibacterial Behavior of Laser-Ablated Copper Nanoparticles

Cited by 21 publications

References 28 publications

Fabrication and Deposition of Copper and Copper Oxide Nanoparticles by Laser Ablation in Open Air

Fabrication and Deposition of Copper and Copper Oxide Nanoparticles by Laser Ablation in Open Air

Antibacterial Activity of Metallic Nanoparticles

Novel Cu-Rich Nano-Precipitates Strengthening Steel with Excellent Antibacterial Performance

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