Antibacterial effect of various shapes of silver nanoparticles monitored by SERS

El-Zahry, Marwa R.; Mahmoud, Amer F.; Refaat, Ibrahim H.; Mohamed, Horria A.; Bohlmann, Holger; Lendl, Bernhard

doi:10.1016/j.talanta.2015.02.022

Cited by 85 publications

(43 citation statements)

References 28 publications

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“…El-Zahry et al compared the antibacterial activity of spherical, triangular and hexagonal shaped AgNPs against Gram negative bacterium E. coli by using conventional disk assay and surface enhanced Raman spectroscopy (SERS). 139 Both methods demonstrated that hexagonal AgNPs exhibited the highest antibacterial activity whereas triangular AgNPs displayed no activity. Recent research revealed that the antimicrobial activity is highest in the case of truncated triangular AgNPs or similar geometries such as hexagonal and octahedral shapes.…”

Section: Factors Affecting the Antimicrobial Activity Of Silver Nanopmentioning

confidence: 99%

Green synthesis of silver nanoparticles: biomolecule-nanoparticle organizations targeting antimicrobial activity

et al. 2019

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Section: Factors Affecting the Antimicrobial Activity Of Silver Nanopmentioning

confidence: 99%

Green synthesis of silver nanoparticles: biomolecule-nanoparticle organizations targeting antimicrobial activity

et al. 2019

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“…As shown in many studies (see, refs. ), the use of such nanomaterials can be accompanied by a drastic aggravation of proliferation and viability of bacteria and cells under study. In other words, chemically synthesized NPs are often disturbing for live bacterial or cell cultures under examination that decreases the precision of SERS‐based identification.…”

Section: Introductionmentioning

confidence: 99%

Bare laser‐synthesized Au‐based nanoparticles as nondisturbing surface‐enhanced Raman scattering probes for bacteria identification

Kögler

Ryabchikov

Uusitalo

et al. 2018

Journal of Biophotonics

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The ability of noble metal-based nanoparticles (NPs) (Au, Ag) to drastically enhance Raman scattering from molecules placed near metal surface, termed as surface-enhanced Raman scattering (SERS), is widely used for identification of trace amounts of biological materials in biomedical, food safety and security applications. However, conventional NPs synthesized by colloidal chemistry are typically contaminated by nonbiocompatible by-products (surfactants, anions), which can have negative impacts on many live objects under examination (cells, bacteria) and thus decrease the precision of bioidentification. In this article, we explore novel ultrapure laser-synthesized Au-based nanomaterials, including Au NPs and AuSi hybrid nanostructures, as mobile SERS probes in tasks of bacteria detection. We show that these Au-based nanomaterials can efficiently enhance Raman signals from model R6G molecules, while the enhancement factor depends on the content of Au in NP composition. Profiting from the observed enhancement and purity of laser-synthesized nanomaterials, we demonstrate successful identification of 2 types of bacteria (Listeria innocua and Escherichia coli). The obtained results promise less disturbing studies of biological systems based on good biocompatibility of contamination-free laser-synthesized nanomaterials.

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“…The surface morphology of blank GNPs and LOR-GNPs were determined using SEM instrument operated at 4-25 Kv on samples gold-sputtered for 120 s at 10 mA under argon gas and low pressure [15].…”

Section: Determination Of Surface Morphologymentioning

confidence: 99%

Formulation of Novel Glycerin Nanoparticles for Enhancement the Solubility of Loratadine; Application to Transdermal Hydrogel Delivery System

Abou-Taleba¹,

Hamdb²,

Abdellatif³

2017

J Nanomed Nanotechnol

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Owing to its slightly aqueous solubility, loratadine (LOR) is used in high doses in different marketed formulations to achieve its desirable bioavailability. The aim of this work is to formulate novel LOR-glycerin nanoparticles (LOR-GNPs) to increase LOR bioavailability. LOR-GNPs were prepared by a precipitation method and then evaluated for such size and morphology using dynamic scattering spectroscopy (DLS) and scanning electron microscopy (SEM), as well as the percentage entrapment efficiency (EE%) of free LOR from GNPs formulations was performed using titration method. Furthermore, the GNPs were formulated in hydrogel. The hydrogel viscosity, spreadability, homogeneity and abdominal rat skin permeation were studied and optimized DLS indicated a successful coating of LOR with glycerin surface that recorded an average size of 334 ± 30 nm with uniform particle size, while SEM showed LOR-NPs in different shapes. The EE% free LOR was found to be satisfactory with a mean content of 98.1 ± 0.3 and a relative standard deviation below 2.0% indicates the reproducibility of the LOR release. LOR-GNPs were formulated as a hydrogel to check their suitability for a dosage form usage. The hydrogel showed accepted viscosity, spreadability, and homogeneity. The results proved that the GNPs penetrated abdominal rat skin. The obtained results showed that LOR-GNPs are considered a new addition for improvement of LOR solubility when applied as a hydrogel. The developed method could be used for different insoluble candidates.

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Antibacterial effect of various shapes of silver nanoparticles monitored by SERS

Cited by 85 publications

References 28 publications

Green synthesis of silver nanoparticles: biomolecule-nanoparticle organizations targeting antimicrobial activity

Green synthesis of silver nanoparticles: biomolecule-nanoparticle organizations targeting antimicrobial activity

Bare laser‐synthesized Au‐based nanoparticles as nondisturbing surface‐enhanced Raman scattering probes for bacteria identification

Formulation of Novel Glycerin Nanoparticles for Enhancement the Solubility of Loratadine; Application to Transdermal Hydrogel Delivery System

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