Antibacterial Effects of Vitamin E: in Vitro Study

Al-Salih, Dalia Abd Al Kader; Aziz, Fitua M.; Mshimesh, Bahir Abdul Razzaq; Jehad, Muhanad T.

doi:10.24126/jobrc.2013.7.2.260

Cited by 25 publications

(3 citation statements)

References 11 publications

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“…The chemical constituents found in the acetone extracts of C. thorelii and C. cotuana could be the main factors contributing to the antibacterial activity. For instance, vitamin E was proved to have an inhibitory effect on K. pneumoniae, S. aureus, E. coli and Staphylococcus epidermidis (31). Stigmasterol was found to be effective against many pathogenic bacteria such as Streptococcus faecalis, E. coli, S. aureus, Pseudomonas fluorescens, K. pneumoniae, and S. typhimurium (32).…”

Section: Antibacterial Activity Of Acetone Extract From C Thorelii An...mentioning

confidence: 99%

Chemical profiles and antibacterial activity of acetone extract of two Curcuma species from Vietnam

Van

Tran²,

Tran³

et al. 2023

Plant Sci. Today

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Curcuma thorelii Gagnep. and Curcuma cotuana Luu, Škorni?k. & H.?.Tr?n are the rare species only found in Southeast Asia. The present study was the first to explore the chemical compositions and antibacterial effects of the whole plant acetone extracts of these 2 species. Altogether 41 and 31 compounds have been identified in C. thorelii and C. cotuana extracts by gas chromatography/mass spectrometry. Accordingly, the C. thorelii extract contained (E)-labda-8(17),12-diene-15,16-dial (33.37%), vitamin E (12.33%), phytol (9.83%) as the major compounds while C. cotuana extract contained predominantly (E)-labda-8(17),12-diene-15,16-dial (14.58%), n-hexadecanoic acid (10.96%), 3,7,11,15-tetramethylhexadec-2-en-1-yl acetate (8.13%), ?-sitosterol (7.97%). In addition, results from disc diffusion assay have shown that C. thorelii acetone extract had inhibitory effects on 5 out of 10 pathogenic bacterial strains such as Bacillus cereus (ATCC 11778), Listeria monocytogenes (ATCC 19111), Staphylococcus aureus (ATCC 25923), S. aureus (ATCC 29213) and S. saprophyticus (BAA750) while C. cotuana acetone extract was found to be effective only against B. cereus. The obtained results showed that the acetone extracts of C. thorelii and C. cotuana possessed several valuable bioactive compounds as well as promising antibacterial activity, which place a good foundation for future pharmaceutical product development.

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Section: Antibacterial Activity Of Acetone Extract From C Thorelii An...mentioning

confidence: 99%

Chemical profiles and antibacterial activity of acetone extract of two Curcuma species from Vietnam

Van

Tran²,

Tran³

et al. 2023

Plant Sci. Today

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“…In our current study, we found that vitamin E exhibited the strongest antimicrobial effect against C. albicans compared to other oral pathogens. Previous studies have shown positive results with vitamin E concentrations ranging from 50 to 400 IU/ml against S. aureus and Staphylococcus epidermidis [ 18 ]. However, in our study, the zone of inhibition for S. aureus was lower compared to C. albicans .…”

Section: Discussionmentioning

confidence: 99%

Assessment of Antimicrobial Activity of Lycopene, Vitamin E, and Lycopene-Vitamin E Combination against Staphylococcus aureus, Streptococcus mutans, Enterococcus faecalis, and Candida albicans: An In Vitro Study

Divyadharsini¹,

Maheswari²,

Rajeshkumar³

2023

Cureus

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Background Lycopene is a naturally occurring compound classified as a carotenoid, a group of pigments responsible for the vibrant colors observed in many fruits and vegetables. It is most commonly associated with red-colored fruits and vegetables, such as tomatoes, watermelon, pink grapefruit, and papaya. Vitamin E encompasses a group of chemical compounds that share a structural relationship with alpha-tocopherol and are essential for the proper functioning of the human body. It is a fat-soluble vitamin and is known for its antioxidant properties. The aim of this study is to evaluate the antimicrobial activity of lycopene extract, vitamin E extract, and their combination against oral pathogens for their potential application in the treatment of oral diseases. Materials and methods The potential antimicrobial effects of extracts derived from lycopene, vitamin E, and their combination were evaluated against oral commensals like Staphylococcus aureus , Streptococcus mutans , Enterococcus faecalis , and Candida albicans . Three concentrations (25 μl, 50 μl, and 100 μl) of the extract were tested. Mueller-Hinton agar (MHA) and Rose Bengal agar (RBA) bases were utilized to determine the zone of inhibition. And the experiments were repeated in triplicate for each group. Results The identification and assessment of the antimicrobial activity of lycopene extract, vitamin E extract, and their combination revealed the greatest efficacy at the highest concentration (100 μl) against all tested microbial strains. Notably, C. albicans exhibited the highest susceptibility compared to the other strains. Vitamin E had the least antimicrobial effect and combination had the highest antimicrobial effect. Conclusion The results of our study demonstrated substantial antimicrobial activity of lycopene and vitamin E. These findings suggest that lycopene and vitamin E can be harnessed in the development of diverse drug formulations for the treatment of oral diseases.

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“…Flowers are pinkish or violet in color and are 10-15 mm across. Flowering season is July to October (Jafri, 1973). Very little information is available about the medicinal value of this plant species.…”

Section: Introductionmentioning

confidence: 99%

Phytochemical screening, antimicrobial and antioxidant properties of Douepia tortuosa Camb., a crucifer endemic to Pakistan

Ullah,

Iqbal,

Ullah

et al. 2024

PAK. J. BOT.

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Douepia tortuosa (D. tortuosa) has not been evaluated for its pharmacological significance prior to this. This study was aimed to identify bioactive compounds occurring in water (AQE), methanol (ME), ethyl acetate (EAE) and n-hexane (HE) extracts of D. tortuosa and to evaluate its antimicrobial and antioxidant potential. The microscopic analysis of the plant powder presented characteristic starch granules and calcium oxalate crystals. The ME presented the best extraction yield value campared to the other solvents. Maximum soluble phenolics content, 793.24 µg GAE/g was found in EAE. The extracts were screened out for the presence of bioactive compounds by using Fourier-Transform Infrared Spectroscopy (FT-IR) and Gas Chromatography-Mass Spectrometry (GC-MS). The FT-IR spectrum of various extracts indicated the dominancy of N-H, C-H, C=O, N-O and C-N functional groups. The GC-MS profiling indicated the presence of a spectrum of substantial medicinal compounds in various extracts including Squalene, Heptacosane, Cis-vaccenic acid, Octadecanoic acid, γ-Sitosterol, vitamin E, Tetracontane, Palmitoleic acid and Dotriacontane. The ME was highly effective antibacterial agent against K. pneumoniae whereas, EAE showed strong antibacterial activity against A. baumannii and E. coli. The EAE and AQE were the best antifungal agents against A. flavus and A. niger. According to IC50 values the AQE (32.422 µg/mL) and EAE (31.6895 µg/mL) has significantly comparable antioxidant activity with standard ascorbic acid (26.917 µg/mL). The plant can be explored in future for the isolation of antimicrobial, antioxidant and anticancer compounds with promising effects.

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Antibacterial Effects of Vitamin E: in Vitro Study

Cited by 25 publications

References 11 publications

Chemical profiles and antibacterial activity of acetone extract of two Curcuma species from Vietnam

Chemical profiles and antibacterial activity of acetone extract of two Curcuma species from Vietnam

Assessment of Antimicrobial Activity of Lycopene, Vitamin E, and Lycopene-Vitamin E Combination against Staphylococcus aureus, Streptococcus mutans, Enterococcus faecalis, and Candida albicans: An In Vitro Study

Phytochemical screening, antimicrobial and antioxidant properties of Douepia tortuosa Camb., a crucifer endemic to Pakistan

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