Antibacterial electrospun chitosan–polyethylene oxide nanocomposite mats containing bioactive silver nanoparticles

Kohsari, Iraj; Shariatinia‬, Zahra; Pourmortazavi, Seied Mahdi

doi:10.1016/j.carbpol.2015.12.075

Cited by 193 publications

(76 citation statements)

References 51 publications

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“…Several reports regarding silver nanoparticles and chitosan based materials in several applications such as tissue engineering, wound dressing or biosensing, among others, can also be found in the literature (Shaik & Kowshik, 2016;Andrade, De Oliveira Vercik, Monteiro, & Da Silva Rigo, 2016;Kohsari, Shariatinia, & Pourmortazavi, 2016;Kolarova, K., Vosmanska, Rimpelova, Ulbrich, & Svorcik, 2015;Kumar-Krishnan et al, 2016).…”

Section: Introductionmentioning

confidence: 98%

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Chitosan based films as supports for dual antimicrobial release

Aranaz

Harris

Navarro‐García

et al. 2016

Carbohydrate Polymers

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Section: Introductionmentioning

confidence: 98%

“…Several reports regarding silver nanoparticles and chitosan based materials in several applications such as tissue engineering and wound dressing can also be found in the literature (Kohsari, Shariatinia & Pourmortazavi, 2016;Kolarova, Vosmanska, Rimpelova, Ulbrich, & Svorcik, 2015).…”

Section: Introductionmentioning

confidence: 98%

Chitosan based films as supports for dual antimicrobial release

Aranaz

Harris

Navarro‐García

et al. 2016

Carbohydrate Polymers

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“…The use of ionic liquid was also mentioned with 1,1,1,3,3,3-hexafluoro-2-propanol [28]. More generally, it has been shown that fine nanofibers can be obtained in chitosan blends with poly (vinyl alcohol) (PVA) [23,25,29,30], gelatin or collagen [2,7,31,32,33,34], silk fibroin [5], polycaprolactone [35] but mainly with poly(ethylene oxide) (PEO) [6,17,18,36,37,38,39,40,41]. Usually, to generate composite fibers the spinning solutions are obtained by mixing the two polymers solutions prepared separately in the same solvent.…”

Section: Introductionmentioning

confidence: 99%

“…With respect to the applications of these chitosan materials obtained by electrospinning, it must be pointed out that they are important for cell cultures [5,37], tissue engineering [6], and also for ion adsorption [14,39,41] or water treatment [15]. It is also necessary to mention that not only electrospun chitin and chitosan are produced but also chitin derivatives [24,45,46].…”

Section: Introductionmentioning

confidence: 99%

Preparation of Pure and Stable Chitosan Nanofibers by Electrospinning in the Presence of Poly(ethylene oxide)

Lemma

Bossard

Rinaudo³

2016

IJMS

102

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Electrospinning was employed to obtain chitosan nanofibers from blends of chitosans (CS) and poly(ethylene oxide) (PEO). Blends of chitosan (MW (weight-average molecular weight) = 102 kg/mol) and PEO (M (molecular weight) = 1000 kg/mol) were selected to optimize the electrospinning process parameters. The PEO powder was solubilized into chitosan solution at different weight ratios in 0.5 M acetic acid. The physicochemical changes of the nanofibers were determined by scanning electron microscopy (SEM), swelling capacity, and nuclear magnetic resonance (NMR) spectroscopy. For stabilization, the produced nanofibers were neutralized with K2CO3 in water or 70% ethanol/30% water as solvent. Subsequently, repeated washings with pure water were performed to extract PEO, potassium acetate and carbonate salts formed in the course of chitosan nanofiber purification. The increase of PEO content in the blend from 20 to 40 w% exhibited bead-free fibers with average diameters 85 ± 19 and 147 ± 28 nm, respectively. Their NMR analysis proved that PEO and the salts were nearly completely removed from the nanostructure of chitosan, demonstrating that the adopted strategy is successful for producing pure chitosan nanofibers. In addition, the nanofibers obtained after neutralization in ethanol-aqueous solution has better structural stability, at least for six months in aqueous solutions (phosphate buffer (PBS) or water).

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“…It is obvious that the CS-PEO mat reveals antibacterial activity which is mainly due to the antibacterial activity of CS. In fact, the antibacterial activities of CS-based materials have frequently been proved [39][40][41].…”

Section: Antibacterial Activitiesmentioning

confidence: 99%