Antibacterial nano biocomposite poly(ε-caprolactone) films with nano Ag-hydroxyapatite filler particles

Hoş, Ayşegül; Tunç, Kenan; Olgun, Uğursoy

doi:10.1080/09276440.2019.1655315

Cited by 5 publications

(1 citation statement)

References 26 publications

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“…Moreover, Hoş et al investigated the potential of a composite film consisting of polycaprolactone and AgNP-coated hydroxyapatite for implant applications. The presence of AgNPs ensured the antibacterial activity against S. aureus , S. epidermidis , and E. coli , while the hydroxyapatite component could ensure an enhanced implant acceptance and bone regeneration capacities [ 157 ]. The antimicrobial character of AgNPs and silicone hydrogel-based composite films against S. aureus , P. aeruginosa , and E. coli was also investigated by Mourad et al The composite films proved their potential in contact lens applications [ 158 ].…”

Section: Inorganic Nanoparticle-based Composite Films For Antimicrobial Applicationsmentioning

confidence: 99%

Inorganic Nanoparticles and Composite Films for Antimicrobial Therapies

Spirescu

Chircov

Grumezescu

et al. 2021

IJMS

107

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The development of drug-resistant microorganisms has become a critical issue for modern medicine and drug discovery and development with severe socio-economic and ecological implications. Since standard and conventional treatment options are generally inefficient, leading to infection persistence and spreading, novel strategies are fundamentally necessary in order to avoid serious global health problems. In this regard, both metal and metal oxide nanoparticles (NPs) demonstrated increased effectiveness as nanobiocides due to intrinsic antimicrobial properties and as nanocarriers for antimicrobial drugs. Among them, gold, silver, copper, zinc oxide, titanium oxide, magnesium oxide, and iron oxide NPs are the most preferred, owing to their proven antimicrobial mechanisms and bio/cytocompatibility. Furthermore, inorganic NPs can be incorporated or attached to organic/inorganic films, thus broadening their application within implant or catheter coatings and wound dressings. In this context, this paper aims to provide an up-to-date overview of the most recent studies investigating inorganic NPs and their integration into composite films designed for antimicrobial therapies.

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Section: Inorganic Nanoparticle-based Composite Films For Antimicrobial Applicationsmentioning

confidence: 99%