Antibacterial properties of composite resins incorporating silver and zinc oxide nanoparticles on<i>Streptococcus mutans</i>and<i>Lactobacillus</i>

Kasraei, Shahin; Sami, Lida; Hendi, Sareh; Alikhani, Mohammad Yousef; Rezaei-Soufi, Loghman; Khamverdi, Zahra

doi:10.5395/rde.2014.39.2.109

Cited by 261 publications

(217 citation statements)

References 37 publications

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“…And composite resins containing silver or zinc oxide nanoparticles exhibited antibacterial activity against streptococcus mutans and lactobacillus [10]. The novel nano antibacterial inorganic filler, that contained a quaternary ammonium salt with long chain alkyl, showed a strong antibacterial property.…”

Section: Introductionmentioning

confidence: 99%

“…Porenczuk A compared the shear bond strength and microscopic assessment of failure modes for a glass-ionomer cement and dentin bonding systems combined with silver nanoparticles, demonstrated AgNPs connection with self-etching dentin bonding system may have a serious clinical impact [9]. Nagano F found that Colloidal Platinum Nanoparticles (CPN) can prolong the durability of bonds, creating a higher conversion at the interface [10]. As a new dental restorative material, new nano-hydroxyapatite composite resin has superior bonding ability and can be used in clinical therapy [7].…”

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confidence: 99%

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The Role of Cell Autophagy in Toxicity Caused by Dental Nanomaterials

Wei¹

2017

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NanomaterialsThe overview of nanomaterials Nanomaterials are defined as materials composed of unbound particles or particles in an aggregate or agglomerate state with one or more external dimensions with a size ranging from 1nm to 100nm [1]. Nanomaterials have a lot of free surfaces and interfaces and there is interaction between the various units. Based on the above characteristics, nanomaterials are featured by surface effect, small size effect, quantum size effect, macroscopic quantum tunneling effect and the dielectric confinement effect. Nanoparticles have lots of unpaired atoms, large specific surface area, less surface defects and can occur in conjunction with the polymer stronger physically or chemically. Added to the polymer material, they can improve the ductility, toughness, strength, barrier properties, heat resistance and dimensional stability of the material. They have been widely used in conventional materials, medical equipment, electronic equipment, paint and other industries. However, nanomaterials will affect the organism and produce a series of toxic effects by inducing oxidative stress and inflammatory response mechanisms in the cell, subcellular and protein levels. The nanomaterials commonly used in dentistryNanometer materials are widely applied in the field of dentistry, including dental restoration, antibacterial, caries treatment, orthodontic, root canal, bonding systems and so on.Adding nanoparticles to dental restoration materials to improve the performance has been widely used in the clinical field. In view of its unpaired atoms, large specific surface area, less surface defects and occurring in conjunction with the polymer either stronger physically or chemically, the novel resin composite exhibited a strong antibacterial property upon the addition of up to 5% nano antibacterial inorganic fillers, there by leading to effective caries inhibition in dental application [2]. The mesoporous silica biomaterials have great potential for serving as both a catalyst and carrier in the repair or regeneration of dental hard tissue [3]. Diatomite-based nanocomposite ceramics are good potential candidates for ceramic-based dental materials [4]. Nano silicon dioxide can also give polymers the characteristics of better viscosity, thermal stability, high strength, less volume shrinkage and of course, durability [5].In clinical endodontics especially root canal and restorative treatments we can see the near future potential of nanoparticles from the application of nanoparticles in the form of solutions for irrigation, medication and as an additive within sealers/restorative materials [6]. GICs can be applied to base plates of Orthodontic and modified denture base well, as which contain chlorhexidine hexametaphosphate nanoparticles and characterize the nanoparticle size shows a stronger antimicrobial activity [7].As for caries treatment, Hannig M said that Analysis of in vitro data indicates that apatite nanoparticles might be effective in reversing lesion progression in the outer but not in the deepe...

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Section: Introductionmentioning

confidence: 99%

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confidence: 99%

The Role of Cell Autophagy in Toxicity Caused by Dental Nanomaterials

Wei¹

2017

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“…Several nanoparticles (eg, zinc oxide, 60,61 silver, [62][63][64] and polyethylenimine 65 ) have been incorporated into dental composites 66 or dental adhesives 67 to inhibit the bacterial growth through several mechanisms. These mechanisms include disruption of the bacterial cell membrane, 68 inhibition of the active transport as well as the metabolism of sugars, generation of reactive oxygen species, 69 displacement of magnesium ions required for the enzymatic activity of oral biofilms, 70 disturbance of the electron transportation across the bacterial membrane, 63 and prevention of DNA replication.…”

Section: Antibacterial Nanotherapymentioning

confidence: 99%

Nanotechnology in dentistry: prevention, diagnosis, and therapy

Neel¹,

Bozec

Pérez³

et al. 2015

IJN

102

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Nanotechnology has rapidly expanded into all areas of science; it offers significant alternative ways to solve scientific and medical questions and problems. In dentistry, nanotechnology has been exploited in the development of restorative materials with some significant success. This review discusses nanointerfaces that could compromise the longevity of dental restorations, and how nanotechnolgy has been employed to modify them for providing long-term successful restorations. It also focuses on some challenging areas in dentistry, eg, oral biofilm and cancers, and how nanotechnology overcomes these challenges. The recent advances in nanodentistry and innovations in oral health-related diagnostic, preventive, and therapeutic methods required to maintain and obtain perfect oral health, have been discussed. The recent advances in nanotechnology could hold promise in bringing a paradigm shift in dental field. Although there are numerous complex therapies being developed to treat many diseases, their clinical use requires careful consideration of the expense of synthesis and implementation.

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“…Applications of nano-sized fillings in the resin matrices have overcome some of the mechanical limitations and have significantly improved their clinical performance. Commonly used nanomaterials include nano-ZnO, 3,4 nano-silica, 18,19 nano-calcium phosphate and calcium fluoride (nano-Ca 3 (PO 4 ) 2 and CaF 2 , respectively), 20 and nano-TiO 2 . 21 In addition to composite resins, the utilization of nanomaterials in dental adhesives has also effectively improved their bonding strengths and mechanical properties.…”

Section: Composite Resins and Bonding Systemsmentioning

confidence: 99%

“…In recent years, nanomaterials have been widely used in the production of dental materials, including light polymerization composite resins 3,4 and bonding systems, coating materials for dental implants, 5 bioceramics, endodontic sealers, 6 and mouthwashes. 7 However, in addition to yielding significant improvements in clinical treatments, the applications of dental nanomaterials have also created growing concerns regarding their biosecurity.…”

Section: Introductionmentioning

confidence: 99%

Application of dental nanomaterials: potential toxicity to the central nervous system

Feng¹,

Chen²,

Wang³

et al. 2015

IJN

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Nanomaterials are defined as materials with one or more external dimensions with a size of 1–100 nm. Such materials possess typical nanostructure-dependent properties (eg, chemical, biological, optical, mechanical, and magnetic), which may differ greatly from the properties of their bulk counterparts. In recent years, nanomaterials have been widely used in the production of dental materials, particularly in light polymerization composite resins and bonding systems, coating materials for dental implants, bioceramics, endodontic sealers, and mouthwashes. However, the dental applications of nanomaterials yield not only a significant improvement in clinical treatments but also growing concerns regarding their biosecurity. The brain is well protected by the blood–brain barrier (BBB), which separates the blood from the cerebral parenchyma. However, in recent years, many studies have found that nanoparticles (NPs), including nanocarriers, can transport through the BBB and locate in the central nervous system (CNS). Because the CNS may be a potential target organ of the nanomaterials, it is essential to determine the neurotoxic effects of NPs. In this review, possible dental nanomaterials and their pathways into the CNS are discussed, as well as related neurotoxicity effects underlying the in vitro and in vivo studies. Finally, we analyze the limitations of the current testing methods on the toxicological effects of nanomaterials. This review contributes to a better understanding of the nano-related risks to the CNS as well as the further development of safety assessment systems.

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Antibacterial properties of composite resins incorporating silver and zinc oxide nanoparticles onStreptococcus mutansandLactobacillus

Cited by 261 publications

References 37 publications

The Role of Cell Autophagy in Toxicity Caused by Dental Nanomaterials

The Role of Cell Autophagy in Toxicity Caused by Dental Nanomaterials

Nanotechnology in dentistry: prevention, diagnosis, and therapy

Application of dental nanomaterials: potential toxicity to the central nervous system

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