Antibacterial properties of silicon nanoparticles

Смирнов, Н. А.; Kudryashov, S. I.; Nastulyavichus, Alena; Rudenko, A. A.; Сараева, И. Н.; Толордава, Э. Р.; Гончуков, С. А.; Romanova, Yu. M.; Ионин, А. А.; Zayarny, D. A.

doi:10.1088/1612-202x/aad853

Cited by 44 publications

(22 citation statements)

References 26 publications

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“…Dental caries is an irreversible disease of the oral cavity, which is multifactorial in nature but mostly driven by a high sugar diet and it manifests as phasic demineralization and remineralization of the hard tissues [1]. It affects people of all ages, with the prevalence rate being 50%, 52.5%, 61.4%, 79.2%, and 84.7% in 5,12,15,[35][36][37][38][39][40][41][42][43][44], and 65-74 year old, respectively according to the National Oral Health Survey report 2002-2003 which makes it a potentially high morbidity related diseases and that's why it has been an important area of focus for dental professionals [2]. Among the main hypothesis for the etiology of dental caries, the specific plaque hypothesis states certain bacterial strains are mainly responsible for dental caries, where bacteria like S. sanguinis were associated with health whereas Lactobacillus, S.mutans, S.salivarius were associated with caries [3].…”

Section: Introductionmentioning

confidence: 99%

Antibacterial Activity of Mouthwash Incorporated with Silica Nanoparticles against S. aureus, S. mutans, E. faecalis: An in-vitro Study

Barma

Kannan

Indiran

et al. 2020

JPRI

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Silica based nanoparticles are used in various fields of medical sciences to diagnose, control disease, for genetic disorders, owing to their size, surface area, biocompatibility and low toxicity. In dentistry, silica nanoparticles have been used as dental filler, teeth whitening agent but limited evidence is there regarding antimicrobial activity against oral pathogens. Therefore, the current study was conducted to assess the anti-bacterial activity of mouthwash incorporated with silica nanoparticles against oral pathogens. Tetraethoxysilane, ammonium hydroxide, absolute ethanol were used and centrifuged to obtain the silica nanoparticle pellet. XRD analysis was done to confirm the characterization of the thus obtained silica nanoparticle. The mouthwash was prepared with the synthesized silica nanoparticle as the main constituent. Agar well diffusion method was used to assess the antimicrobial activity against S. mutans, S. aureus and E. faecalis. The XRD analysis confirmed the amorphous nature of the synthesized silica nanoparticles. The zone of inhibition was found to increase as the concentrations increased mainly for S. aureus and E. faecalis. The synthesized nanoparticles incorporated mouthwash showed good potential as antimicrobial agents against strains of gram positive bacteria. Further animal studies/in vivo research should be conducted to validate the above findings.

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Section: Introductionmentioning

confidence: 99%

Antibacterial Activity of Mouthwash Incorporated with Silica Nanoparticles against S. aureus, S. mutans, E. faecalis: An in-vitro Study

Barma

Kannan

Indiran

et al. 2020

JPRI

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“…Nanostructured surfaces of different materials exhibit unexpected and unprecedented bactericidal effects regarding pathogenic bacteria, which is usually related either to photochemical reaction of gaseous oxygen with composing nanocrystallites, yielding in reactive oxygen species and singlet oxygen [1][2][3][4][5], or to mechanical reaction of bacterial membranes to sharp surface nanoroughness [6][7][8]. Specifically, in the case of Si a broad variety of its nanomorph-nanospike [6], nanosheets [7] and nanoparticles (NPs) [9] were demonstrated to be bactericidal.…”

Section: Introductionmentioning

confidence: 99%

Surface-Enhanced IR-Absorption Microscopy of Staphylococcus aureus Bacteria on Bactericidal Nanostructured Si Surfaces

et al. 2019

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Surface-enhanced IR absorption (SEIRA) microscopy was used to reveal main chemical and physical interactions between Staphylococcus aureus bacteria and different laser-nanostructured bactericidal Si surfaces via simultaneous chemical enhancement of the corresponding IR-absorption in the intact functional chemical groups. A cleaner, less passivated surface of Si nanoripples, laser-patterned in water, exhibits much stronger enhancement of SEIRA signals compared to the bare Si wafer, the surface coating of oxidized Si nanoparticles and oxidized/carbonized Si (nano) ripples, laser-patterned in air and water. Additional very strong bands emerge in the SEIRA spectra on the clean Si nanoripples, indicating the potential chemical modifications in the bacterial membrane and nucleic acids during the bactericidal effect.

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“…Silicon nanoparticles obtained in alcohol probed to have a greater hydrophobicity (Figure 5c,d). silicon NP (prepared in water) coating on the silicon wafer (g,j) (Reproduced with permission from [108]. IOP Publishing, 2018).…”

Section: Silicon-based Nanomaterials Synthesized By Laser Ablation Fomentioning

confidence: 99%

Advances in Laser Ablation Synthesized Silicon-Based Nanomaterials for the Prevention of Bacterial Infection

Martínez-Carmona

Vallet‐Regí

2020

Nanomaterials

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Nanomaterials have unique properties and characteristics derived from their shape and small size that are not present in bulk materials. If size and shape are decisive, the synthesis method used, which determines the above parameters, is equally important. Among the different nanomaterial’s synthesis methods, we can find chemical methods (microemulsion, sol-gel, hydrothermal treatments, etc.), physical methods (evaporation-condensation, laser treatment, etc.) and biosynthesis. Among all of them, the use of laser ablation that allows obtaining non-toxic nanomaterials (absence of foreign compounds) with a controlled 3D size, has emerged in recent years as a simple and versatile alternative for the synthesis of a wide variety of nanomaterials with numerous applications. This manuscript reviews the latest advances in the use of laser ablation for the synthesis of silicon-based nanomaterials, highlighting its usefulness in the prevention of bacterial infection.

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Antibacterial properties of silicon nanoparticles

Cited by 44 publications

References 26 publications

Antibacterial Activity of Mouthwash Incorporated with Silica Nanoparticles against S. aureus, S. mutans, E. faecalis: An in-vitro Study

Antibacterial Activity of Mouthwash Incorporated with Silica Nanoparticles against S. aureus, S. mutans, E. faecalis: An in-vitro Study

Surface-Enhanced IR-Absorption Microscopy of Staphylococcus aureus Bacteria on Bactericidal Nanostructured Si Surfaces

Advances in Laser Ablation Synthesized Silicon-Based Nanomaterials for the Prevention of Bacterial Infection

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