Antibacterial Properties of Silver‐Doped Titania

Abstract

Silver has been known to exhibit strong cytotoxicity towards a broad range of micro-organisms. Silver composites with a tailored slow silver-release rate are currently being investigated for various applications. [1] Silver has an oligodynamic effect, that is, silver ions are capable of causing a bacteriostatic (growth inhibition) or even a bactericidal (antibacterial) impact. Nanometer-sized inorganic particles and composites display unique physical and chemical properties and represent a unique class of materials in the development of novel devices, which can be used in numerous physical, biological, biomedical, and pharmaceutical applications. [2] Silver composites have applications in many industries, such as aerospace, surface coatings (e.g., in refrigerators, food processing, kitchen furniture), and for use in hospitals. Research indicates that silver is also effective in purification systems for disinfecting water or air. [3][4][5][6] However, in order to make the use of silver economical, there is a need to find cheaper ways of using silver in potential applications without jeopardizing its functionalities.The bactericidal behavior of silver nanoparticles is attributed to the presence of electronic effects, which are a result of the changes in the local electronic structure of the surfaces of the smaller-sized particles. These effects are considered to be contributing towards an enhancement of the reactivity of silver-nanoparticle surfaces. It has been reported that ionic silver strongly interacts with thiol groups of vital enzymes and inactivates them. It has been suggested

Highly synergistic antimicrobial activity of spherical and flower-like hierarchical titanium dioxide/silver composites

“…The deconstructed peak at 458.1 eV matches well with the presence of Ti 3+ , which can arise from the incorporation of silver on the matrix of TiO 2 [32] . 10 The effect of reactant concentration on the structures of TiO 2 /Ag composites was investigated. When the molar composition of Ti/Ag was 100 or 75, all the diffraction peaks matched well with the anatase TiO 2 (JCPDS standard card No.…”

“…Cu [8] , Zn [9] , Ag [10] and Fe [11] ) and TiO 2 /non-metals composites [12][13][14] , so as to efficiently extend their utility as biomedical materials. Among these composites, TiO 2 /Ag composites are more potent antibacterial agents due to the fact that Ag nanoparticles (Ag NPs) deposited in TiO 2 matrix act as a conductor and charge separators for blocking electron-hole recombination, resulting in maximizing the production of ROS [15][16][17] .…”

Large scale photochemical synthesis of M@TiO2 nanocomposites (M = Ag, Pd, Au, Pt) and their optical properties, CO oxidation performance, and antibacterial effect

“…Organic frameworks [6,7] and metal oxide supports [8][9][10] have frequently been used to maintain the dispersion of such noble metal nanoparticles. Due to their low price and ability to be prepared on a large scale, and since they are beneficial or, at worst, inert in processes catalyzed by noble metals, inorganic supports are preferred.…”

One-step synthesis of size-tunable Ag nanoparticles incorporated in electrospun PVA/cyclodextrin nanofibers

“…(Morones et al, 2005). Moreover, we observed that the increase in the inhibition zone was more distinctive for S. aureus compared to E. coli as the Ag-NP size get smaller and this could be attributed to the cellular wall content differences between Gram-positive and Gram-negative bacteria as discussed by Thiel et al (2007).…”