Antibacterial silver-doped bioactive silica gel production using molten salt method

Abstract

Due to broad-spectrum antimicrobial activity, silver nanoparticles have great application potential in disinfection of contaminated water. The aim of this research was the introduction of a fast and simple method titled as ''molten salt method'' for the production of silverdoped bioactive silica gel (SG) nanocomposite. In this method, SG was imposed into the molten salt of silver nitrate at 150 and 300°C for various times. Interestingly, molten salt method was not utilized any reducing reagent or other chemicals unless molten silver nitrate. The synthesis and fixing of nanoparticles into the support were done in \60 min. The prepared silver/SG nanocomposite was evaluated using scanning electron microscope (SEM), energy dispersive X-ray fluorescence, leaching test and antibacterial test. SEM images showed that the contact of SG with the molten salt caused the formation of nanoparticles on the SG. On the other hand, increasing the contact time, it led to a larger and increased number of particles. The antibacterial tests demonstrated that this composite is suitable for using as antibacterial material. The test of elution with water indicated that the prepared nanocomposite is stable and the amount of the released silver in the water was negligible.

Optimization of silver-containing bioglass nanoparticles envisaging biomedical applications

“…Bioactive glass is a particularly interesting biomaterial, since it is the most bioactive material available that is dissolvable under biological conditions (in vitro and in vivo) and provides biologically active ions, which enable the bone regeneration, and also the soft tissue regeneration and wound healing [9][10][11]. Bioglass® is generally composed by SiO 2 -CaO-P 2 O 5 and Na 2 O and it can mainly be synthesized through two approaches: melting or sol-gel [7,12,13]. Since variations in the ratio of precursors or in the production apparatus could result in distinct nanoparticles' morphology and shape [5], several bioglass nanoparticles have been synthesized since 1969 [10,11,14].…”

Diffusion of Cu Ions into Nanoclay by Molten Salt Ion Exchange for Antibacterial Application

“…Clay minerals' physical properties are a component in many therapeutic products, serving as a carrier of antibacterial agents or as a means of eliminating toxic substances from the body. 3 Clay-based antimicrobials exist as drugs, small organic molecules and nanoparticles. Higher protection and efficacy are obtainable provided the nanoparticles are introduced into the clay mineral's layer and are also adsorbed on the outer places.…”

Rapidly-Dissolving Silver-Containing Bioactive Glasses for Cariostatic Applications

“…Calcium and phosphorous are incorporated in order to increase remineralization effects, as both are key components of hydroxyapatite (HA); which chemically resembles the mineral component of dentine and enamel [ 28 ]. Silver is included in ionic form as it is antibacterial [ 29 , 30 , 31 , 32 , 33 ], even if the mechanism of action is not fully understood [ 34 ]. Several attempts to explain the antibacterial effect of silver have been developed [ 29 , 34 ].…”