2022
DOI: 10.1016/j.ijpharm.2022.121782
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Antibiotic-loaded lipid-based nanocarrier: A promising strategy to overcome bacterial infection

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Cited by 16 publications
(11 citation statements)
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“…On the other hand, an equally high eradication rate was observed with CA-AMX (20 mg/kg) and CA-DHA-AMX (10 and 20 mg/kg). It is suggested that the membrane proteins changed and the permeability and accessibility of the antibiotic led to a significant decrease in the effective dose ( Henostroza et al, 2022 ).…”
Section: Resultsmentioning
confidence: 99%
“…On the other hand, an equally high eradication rate was observed with CA-AMX (20 mg/kg) and CA-DHA-AMX (10 and 20 mg/kg). It is suggested that the membrane proteins changed and the permeability and accessibility of the antibiotic led to a significant decrease in the effective dose ( Henostroza et al, 2022 ).…”
Section: Resultsmentioning
confidence: 99%
“…(b) Schematic representation of potential action mechanism by which LNPs can interact with bacterial cell membrane to invade the cell and act as antibacterial/microbial agent. The image has been reused with permission from 153. ''Assembled with BioRender.com''.…”
mentioning
confidence: 99%
“…The greater the surface charge, the greater the electrostatic repulsion between two liposomes. Small particle size and high zeta potential—particularly above 30 mV in modulus (Chen et al 2019 ; Anali Bazán Henostroza et al 2022 )—increase the stability of liposomes. A positive zeta potential can be achieved by adding cationic compounds to liposomes, such as dioleoylphosphatidylethanolamine (DOPE) (Ding et al 2009 ) and 1,2-dioleoyl-3-trimethylammonium propane (DOTAP) (Tonguc-Altin et al 2015 ).…”
Section: Liposomesmentioning
confidence: 99%
“…The main issue is poor stability compared to other drug carriers (Roohinejad et al 2018 ; Thorn et al 2021 ). Traditional liposomes greater than 100 nm are rapidly cleared from blood circulation by circulating macrophages or dendritic cells as part of the reticuloendothelial system (Buya et al 2021 ; Anali Bazán Henostroza et al 2022 ). Hydrophilic polymers such as polyethylene glycol, pectin or chitosan can protectively coat the surface of liposomes, increasing their residence time in the blood circulation (Anabousi et al 2006 ; Icriverzi et al 2019 ; Buya et al 2021 ).…”
Section: Liposomesmentioning
confidence: 99%