1995
DOI: 10.1016/0190-9622(95)90119-1
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Antibiotic prophylaxis in dermatologic surgery

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Cited by 135 publications
(85 citation statements)
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“…Intravenous prophylactic antibiotics for surgical wound infections have been shown to be most effective when administered within the 2 hours before surgery, 4 and are commonly given within 30 minutes of an operation. 5,6 The optimal timing for intramuscular or oral administration for wound infection prophylaxis is not as clear; no data exist to support the common recommendation of administering oral prophylaxis 1 or 2 hours before a procedure. 5,7 The translation of the timing recommendations of oral antibiotics for endocarditis prophylaxis to cutaneous surgery is complicated by the associated variabilities in absorption, dis- Normal healing but all 3 of the following: increased erythema, edema, and increased pain; or 1 of the latter combined with hemoserous discharge…”
Section: Commentmentioning
confidence: 99%
“…Intravenous prophylactic antibiotics for surgical wound infections have been shown to be most effective when administered within the 2 hours before surgery, 4 and are commonly given within 30 minutes of an operation. 5,6 The optimal timing for intramuscular or oral administration for wound infection prophylaxis is not as clear; no data exist to support the common recommendation of administering oral prophylaxis 1 or 2 hours before a procedure. 5,7 The translation of the timing recommendations of oral antibiotics for endocarditis prophylaxis to cutaneous surgery is complicated by the associated variabilities in absorption, dis- Normal healing but all 3 of the following: increased erythema, edema, and increased pain; or 1 of the latter combined with hemoserous discharge…”
Section: Commentmentioning
confidence: 99%
“…10 As feridas cutâneas podem ser classificadas de acordo com a operação em: limpas, limpas contaminadas, contaminadas e infectadas. 11 As feridas limpas apresentam baixa incidência de infecção e não necessitam antibioticoterapia profilática. Nas feridas limpas contaminadas preconiza-se a antibioticoterapia de forma seletiva, na dependência do local e da natureza da operação, da sua duração e do estado geral do paciente.…”
Section: Os Pacientes Asa 2 Eunclassified
“…Há relação entre o momento de infusão do antibiótico e o risco de infecção do sítio cirúrgico e os melhores resultados foram obtidos com a administração dos antibióticos de infusão rápida trinta minutos anteriormente a incisão da pele 14 . Há evidências de que o antibió-tico fica retido no coágulo que sela a ferida; assim, quando administrado após a operação, não consegue penetrar na fibrina e esta, por sua vez, também impede a penetração de bactérias do meio externo 11 . …”
Section: Os Pacientes Asa 2 Eunclassified
“…Therefore, in keeping with recent recommendations, they received antibiotic prophylaxis on the day of surgery with 1 g of cephalexin at the time of surgery, followed by 500 mg 6 hours later. 4 Twenty-four patients underwent surgery for primary lesions, and 4 patients underwent surgery for recurrences. Twenty-seven lesions were basal cell carcinomas: 14 were infiltrating, 2 basosquamous, and the rest nodular.…”
Section: Methodsmentioning
confidence: 99%