Antibiotic resistance in urban and hospital wastewaters and their impact on a receiving freshwater ecosystem

Proia, Lorenzo; Anzil, Adriana; Subirats, Jèssica; Borrego, Carles M.; Farré, Marinella; Llorca, Marta; Luis, Balcázar Jose; Servais, Pierre

doi:10.1016/j.chemosphere.2018.04.163

Cited by 138 publications

(51 citation statements)

References 65 publications

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“…Hospital wastewater contains a group of organisms that cause various diseases, and it plays a major role in the spreading of drug-resistant pathogens by becoming a pollutant by improving the growth, propagation, and warming properties in the environment. Especially wastewaters that are involved in lakes and rivers cause very important problems [17]. These conditions have become a major problem for public health, particularly in developing countries as they can be transmitted directly or indirectly to human beings and animals from the aquatic food web [18].…”

Section: Medical Wastesmentioning

confidence: 99%

“…Pharmaceuticals are emerging as aquatic ecosystem contaminants, and their concentrations in water bodies are an increasing environmental issue [17][18][19][20]. Although their positive effect on health (human, veterinary, water culture, etc.)…”

Section: Medical Wastesmentioning

confidence: 99%

“…In a recent study by Varol and Sünbül [20], different levels of 37 antibiotics, 10 metals, and 19 organochlorine pesticides were analyzed in 6 fish species from the Karakaya Dam Reservoir (HEPP), Turkey. Fish is one of the groups used as bioindicators for the evaluation of water quality and pollutants such as antibiotics and heavy metals and are taken directly from the water column and trophic transfer [17,18,20]. Therefore, for human health, it is very important to determine the levels of these pollutants in consumable fish species because the consumption of these fish species is the main way of exposure to pollutants.…”

Section: Medical Wastesmentioning

confidence: 99%

“…The ozonation, chlorination, and UV disinfection used independently or in combination in the disinfection of medical and pharmaceutical wastes are among the most investigated subjects and have demonstrated several performances. The use of coagulation technology to reduce antibiotic-resistant genes in wastewater treatment plants has been found to be more effective [17]. Moreover, graphene-based TiO 2 composite photocatalysts are efficient methods for the removal of antibiotics, antibiotic-resistant bacteria, and genes from wastewaters [17].…”

Section: Medical Wastesmentioning

confidence: 99%

“…The use of coagulation technology to reduce antibiotic-resistant genes in wastewater treatment plants has been found to be more effective [17]. Moreover, graphene-based TiO 2 composite photocatalysts are efficient methods for the removal of antibiotics, antibiotic-resistant bacteria, and genes from wastewaters [17]. In addition, as a result of administration of TiO 2 photocatalysis under UV irradiation in combination with H 2 O 2 , good removal efficiencies of antibiotic-resistant bacteria and antibiotic-resistant genes (both intracellular and extracellular forms) from aquatic media were reported.…”

Section: Medical Wastesmentioning

confidence: 99%

See 4 more Smart Citations

Introductory Chapter: Current Status of Freshwater Ecosystems

Gökçe¹

2019

Limnology - Some New Aspects of Inland Water Ecology

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Section: Medical Wastesmentioning

confidence: 99%

Section: Medical Wastesmentioning

confidence: 99%

Section: Medical Wastesmentioning

confidence: 99%

Section: Medical Wastesmentioning

confidence: 99%

Section: Medical Wastesmentioning

confidence: 99%

See 3 more Smart Citations

Introductory Chapter: Current Status of Freshwater Ecosystems

Gökçe¹

2019

Limnology - Some New Aspects of Inland Water Ecology

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Preparation of MgAl layered double oxides and its adsorption kinetics for ciprofloxacin hydrochloride in water

Gao

Huang

et al. 2022

Env Prog and Sustain Energy

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Magnesium aluminum carbonate hydrotalcites (MgAl‐LDHs) were prepared by a coprecipitation method using magnesium nitrate and aluminum nitrate as raw materials, and then calcined at high temperature to obtain hydrotalcite‐like MgAl layered double oxides (MgAl‐LDOs). With ciprofloxacin hydrochloride as the target pollutant, and the adsorption kinetics of ciprofloxacin hydrochloride by MgAl‐LDOs were assessed. The results show that: MgAl‐LDHs and MgAl‐LDOs are both mesoporous adsorbent materials. After MgAl‐LDHs were calcined at 400°C, their layered structure began to collapse partially. At the same time, their specific surface area, pore volume, and average pore diameter increased from 123.593 m2/g, 0.666 cm3/g, and 21.54 nm to 185.908 m2/g, 1.414 cm3/g, and 30.42 nm, respectively. The ability of MgAl‐LDOs to remove ciprofloxacin hydrochloride in water is much greater than that of MgAl‐LDHs. The research has shown that when the concentration of ciprofloxacin hydrochloride solution is 10 mg/L, at a pH of 5, and a temperature of 25°C, the equilibrium adsorption capacity can reach 22.69 mg/g in 420 min. The results of the quasi‐first‐order kinetic model and the quasi‐second‐order kinetic model show that the parameter R2 of MgAl‐LDOs adsorption of ciprofloxacin hydrochloride exceeds 0.94. The fitting parameters qe = 22.96 mg/g (10 mg/L) and qe = 107.02 mg/g (50 mg/L) in the quasi‐first‐order kinetic model, and the fitting parameters qe = 25.02 mg/g (10 mg/L) and qe = 112.72 mg/g (50 mg/L) in the quasi‐second‐order kinetic model are practically consistent with the measured equilibrium adsorption capacity.

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Characterization of antibiotic resistance genes and bacteria in a municipal water resource recovery facility

Rajabi

Farajzadeh

Dehghanzadeh

et al. 2022

Water Environment Research

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Municipal water resource recovery facilities (WRRFs) are important sources of antibiotic‐resistant bacteria and genes (ARB and ARGs). In this study, antibiotic‐resistant total heterotrophic bacteria (THBR) counts (CFU/ml) cultivated from influent, effluent of activated sludge process, and outflow of disinfection unit of an urban WRRF were investigated for the presence of 16, 32, 64, and 128 μg/ml of nine antibiotics. The isolates of Pseudomonas spp., Acinetobacter spp., and Escherichia coli obtained from effluent of activated sludge process were subjected for molecular identification by detecting the 16S rRNA gene sequences. Additionally, using the polymerase chain reaction method (PCR), the isolates were investigated for the presence of blaSHV, blaTEM, blaCTX‐M, blaVIM, sul1, and qnrS genes. According to the results, the abundance of THBR counts was not significantly reduced by the biological treatment except for cefixime and sulfamethoxazole; it also increased for some antibiotics after disinfection unit. The average removal efficiency of THBR resistant to ciprofloxacin, sulfamethoxazole, and ceftazidime were 7.9 ± 1.7%, 41.8 ± 2.1%, and 14.4 ± 6.2%, respectively. Also, all the tested isolates were resistant to at least four antibiotics. For all antibiotics, the resistance ratio (THBR/THB) significantly increased in the effluent and after chlorination unit. Among 12 resistant isolates, blaTEM and sul1 genes were the most frequently detected ones involved in 92% and 83% of the isolates, respectively. Both blaTEM and sul1 genes were found in 100% of E. coli, and 83% and 67% of Pseudomonas spp. isolates, respectively. Further efforts are necessary to limit the transmission of ARB and ARGs from WRRFs into the environment and prevent human health threats. Practitioner Points The ratio of resistance significantly increased after biological treatment. Up to 40% of heterotrophic bacteria in the effluent was antibiotic resistant. blaTEM and sul1 genes were more prevalent (92%) in all isolates of bacteria. Both blaTEM and sul1 genes were found in 100% of E. coli isolates. Pseudomonas spp. holds blaTEM and sul1 genes in 83% and 67% of isolates, respectively.

show abstract

Antibiotic resistance in urban and hospital wastewaters and their impact on a receiving freshwater ecosystem

Cited by 138 publications

References 65 publications

Introductory Chapter: Current Status of Freshwater Ecosystems

Introductory Chapter: Current Status of Freshwater Ecosystems

Preparation of MgAl layered double oxides and its adsorption kinetics for ciprofloxacin hydrochloride in water

Characterization of antibiotic resistance genes and bacteria in a municipal water resource recovery facility

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