Antibiotic resistance in urinary tract infections: A re-visit after five years and experience over two sites

Abstract

<jats:sec><jats:title>Objective</jats:title><jats:p> The aim of this study was to repeat a previous audit, performed from 2009 to 2013, for the cohort of 2018 to determine how the resistance rates in urinary pathogens in women over 18 years of age have changed. A secondary aim of the study was to use resistance data from a different UK hospital in the same year to compare differences in resistance rates across different geographic locations </jats:p></jats:sec><jats:sec><jats:title>Study design</jats:title><jats:p> This was a retrospective study of all positive urine cultures grown from female patients attending two different hospitals in the year 2018. Resistance patterns were analysed. </jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p> The resistance rate to co-amoxiclav continues to increase with amoxicillin retaining high resistance patterns. There are some significant differences in resistance patterns between the different locations. </jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p> Antimicrobial resistance is a significant problem in the UK particularly in antibiotics used to treat UTI. These patterns can vary across different geographical locations and over time; therefore, up-to-date knowledge of local anti-biotic resistance is essential when making an appropriate prescription choice. </jats:p></jats:sec>

Meta-Analysis of Prevalence of CFTR Mutations in Middle East Populations Antimicrobial Resistance among Urinary Tract Isolates of Patients Suffering from Urinary Tract Infections (UTIs): A Retrospective Observational Study

“…Aforementioned study indicated that the susceptibility of E. coli ranged from 66% for amoxicillin to 94% for ciprofloxacin and 100% for both nitrofurantoin and fosfomycin. Another study indicated increased pattern of resistance rate to co-amoxiclav along with amoxicillin in urinary pathogens among women in a UK hospital [12].…”

Prospective Study and Analysis of the Pattern of Antimicrobial Utilization for Urinary Tract Infection in Tertiary Care Hospital

“…Of the many possible factors responsible for these developments, the overuse and inappropriate prescribing of broad-spectrum antibiotics have been implicated. 5 Hospital inpatient prescription of antimicrobial drugs has been major concern in the last few decades. For the purchasers of healthcare services and administrators, antibiotic drugs account for a major proportion of the escalating drug budget, especially in hospitals.…”