Antibiotic Resistance Patterns in a University Hospital in Al-Kharj City

Abstract

Introduction: Antibiotics are medications that are used to kill a bacterium which causes different infections. The misuse of these medications has contributed to the development of bacterial resistance. In order to predict the efficacy of the antimicrobial drugs and to guide antimicrobial therapy, antibiogram should be used.
 Objective: This study aims to explore the Antibiotic resistance patterns in a university hospital in AL-kharj city.
 Methods: Data from a university hospital in Al-Kharj city were used to assess the in vitro antimicrobial susceptibility rates for different types of bacteria. We included all bacterial and fungal cultures in the last 2 years.
 Results: The most common bacterium was E. coli and the most common fungus pathogen was Candida albicans. There was a low resistance rate to gentamicin, imipenem, meropenem and amikacin for the studied bacteria pathogens and high resistance rate for some antibiotics such as erythromycin, tetracycline and ampicillin.
 Conclusion: The physicians should follow the treatment guidelines and they should know the susceptibility rate of different bacteria to prescribe antibiotics appropriately.

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“…[17] Ahmed and Khan conducted a study in a university hospital in Al-Kharj and reported that the most common bacteria were E. coli (26.58%) followed by K. pneumoniae (16.45%), Enterococcus faecalis (13.92%), P. aeruginosa (12.65%), and S. aureus (12.65%). [18] Ahmed et al stated that in a public hospital in Al-Kharj, ESKAPE pathogens (Enterococcus faecium, S. aureus, K. pneumoniae, Acinetobacter baumannii, P. aeruginosa, and Enterobacter) cause nearly half of the infections that were caused by bacteria and the most common ESKAPE pathogen was K. pneumoniae followed by P. aeruginosa. [19] The SSI rate in the present study was 2.32%.…”

Prevalence of Infections, the Rate of Bacterial Resistance and Antibiotics Use in Al-kharj: Narrative Review

“…doctors' offices and emergency departments, at least 28% of antibiotic courses prescribed annually are unnecessary, which makes improving the prescribing and the use of antibiotics a national priority [1].…”

Prevalence of Gram-negative and Gram-positive Bacteria and Antibiotic Resistance Rates at a Military Hospital in Riyadh Region

“…Similarly, the resistance rate of Klebsiella pneumonia was high only to ampicillin (susceptibility rate=1%) and Nitrofurantoin (susceptibility rate=37%). The resistance Ahmed and Khan reported that in a University Hospital in Al-Kharj, the most common bacteria were Escherichia coli (26.58%), Klebsiella pneumonia (16.45%) and that the percentages of Enterococcus faecalis, Pseudomonas aeruginosa and Staphylococcus aureus were 13.92%, 12.65% and 12.65% respectively 14. Moreover, Masoud et al found that Najran Area, the most prevalent bacteria isolated were Escherichia coli (35.63%), Klebsiella pneumoniae (18.08%), and Staphylococcus aureus (14.89%).…”