Antibiotic Resistance Profile of Salmonella Enterica subsp. Enterica Isolated from Dog and Human Samples in Türkiye: The Case of Kastamonu

Abstract

Salmonellosis is of great importance for humans and animals. Companion animals, particularly dogs, can be asymptomatic carriers of Salmonella, and thus have been ignored as a source of salmonellosis. They can also spread multidrug resistant Salmonella strains via dog feces, causing inconvenience in the treatment of human salmonellosis. The purpose of this study was to investigate the presence of Salmonella enterica subsp. enterica isolates from collected dog feces belonging to dogs residing at the Municipal Dog Shelter, Anatolian Shepherd Dog Farm, and from blood, stool, and joint fluid samples from humans with symptoms of gasroenteritis, abdominal, and joint pain. In addition to this, the antibiotic resistance profiles of Salmonella enterica subsp. enterica isolates were examined. A total of 45 human and 11 dog Salmonella enterica subsp. enterica isolates were obtained. The 11 Salmonella enterica subsp. enterica recovered from dogs were identified as S. Infantis, S. Enteritidis, and S. Typhimurium, which correspond to serovars priotorized for human health. Almost all human isolates (42/45) and all dog Salmonella isolates (11/11) were found to be resistant to one or five, and one or four of the tested antibiotics, respectively, but not for CFZ, CAZ, CST in human and CFZ, CAZ, CST, ETP in dog Salmonella isolates. Common resistance profiles in dog and human origin Salmonella isolates were GEN/AMK, AMP/GEN/CIP/SXT, AMP/CIP, SXT. Exhibition of the common resistance profiles against antibiotics recommended in the treatment of human salmonellosis should not be ignored. Companion animals should be monitored for carrying Salmonella and spreading antibiotic resistant bacteria.