Antibiotic sensitivity of theBacteroides fragilisgroup in Denmark

Abstract

Resistance rates to 9 antibiotics were determined for 370 isolates of the Bacteroides fragilis group submitted during a 5‐month period in 1990‐91 from 6 laboratories in Denmark. There was no resistance to imipenem (MIC > 8 mg/1) or metronidazole (MIC > 16 mg/1), while resistance to ampicillin was the rule (97% at > 4 mg/1) and to ceftriaxone rather common (19% at > 32 mg/1). Resistance was uncommon to cefoxitin (0.5% at > 32 mg/1), cefotaxime (6% at > 32 mg/1), piperacillin (7% at > 64 mg/1), ampicillin/sulbactam (1% at > 16 mg/1), and clindamycin (3% at > 4 mg/1). Two hundred and thirty‐nine strains were Bacteroides fragilis. The 131 other strains were generally more resistant than the Bacteroides fragilis strains. For 5 antibiotics the Bacteroides fragilis had a significantly lower MIC in western than in eastern laboratories. For the group with other strains there was no significant difference.