Antibiotic susceptibility of microbiota members Escherichia coli strains isolated from stool samples of patients attended Kırıkkale Yüksek İhtisas Hospital in ten months

Abstract

Objective: Antibiotic resistance has turned into a global public health problem in all over the world. Intestinal flora bacteria perform many important functions for human health. As a member of microbiota Escherichia coli cause many infections. This study was aimed to determine antibiotic susceptibility of microbiota member E. coli isolates against to the antibiotics that used in treatment. Methods:One hundred and fifty stool samples, which were sent to Kırıkkale Yüksek İhtisas Hospital microbiology laboratory in a period of between March to December 2013 to study fecal occult blood test and were determined as "negative", were included in this study. E. coli isolates were performed antibiotic susceptibility test by the Kirby Bauer disk diffusion method according to the recommendations of the Clinical Laboratory Standards Institute (CLSI).Results: A total of 70 out of 150 E. coli isolates were sensitive to all antibiotics that used in the study. Twenty four (16%) isolates were found to be ESBL producers. All isolates were found sensitive to carbapenems. Conclusion:It was reached the conclusion that monitoring to resistance profiles of microbiota member E. coli isolates, especially in specific group patients in addition to infection agents, is important for giving direction to empirical therapy.

Relationships between Virulence Factors and Antimicrobial Resistance among <italic>Escherichia coli</italic> Isolated from Urinary Tract Infections and Commensal Isolates in Tehran, Iran

“…Similar to other investigations, different antibiotic resistance patterns were observed in UPEC compared with commensal isolates [ 31 , 32 ]. We found that the resistance rate of commensal isolates to third-generation cephalosporins and amikacin was higher than was observed in reports from other countries [ 31 – 33 ].…”