Antibiotic susceptibility pattern in urinary isolates of gram negative bacilli with special reference to AmpC β-lactamase in a tertiary care hospital

Patel, Mitesh; Trivedi, Grishma; Patel, Sachin M.; Vegad, Mahendra

doi:10.4103/0974-7796.62915

Cited by 19 publications

(13 citation statements)

References 5 publications

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“…Study conducted by Wazait HD et al, in 2001 reported 0.90% and by Patel MH et al, in 2010 reported 34% resistant to ceftazidime. 18,19 This shows that resistance among pseudomonas species has increased more over last 10 years. Highest resistance was found to aminoglycosides (tobramycin) 92.30%.…”

Section: Discussionmentioning

confidence: 95%

Study of incidence and risk factors of urinary tract infection in catheterised patients admitted at tertiary care

Kakaria¹,

Ashish²

2018

Int J Res Med Sci

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Background: Catheter-associated urinary tract infections (CAUTIs) are the most common nosocomial infection and a leading cause of morbidity and mortality in hospitalized patients. The aim of this study was to determine the incidence and risk factors of urinary tract infection in catheterised patients in a tertiary care hospital.Methods: Total of 200 patients above 16 years in whom an indwelling Foley‘s catheter inserted were taken in the study. A urine specimen was obtained aseptically and culture done on nutrient agar, sheep blood agar and MacConkey agar plates. After incubation of 24 hours, colony count done for organisms showing growth and colony count ≥105 was taken significant.Results: The incidence of CAUTI in the present study was 31%. Higher incidence of CAUTI (56.46%) was found in female sex as compared to males (43.54%). Incidence of CAUTI was found higher in first weeks (54.83%). Incidence among diabetes patients is found more (63.33%). Most common isolate found was E. coli (38.71%) among all uropathogens. Uropathogens isolated from CAUTI are more resistant to antimicrobials.Conclusions: It is must to implement following strategy for reducing the risk of infection due to indwelling catheters: 1. reducing the duration of catheterization 2. Use antibacterial substance coated catheter 3. Strict infection control measures.

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Section: Discussionmentioning

confidence: 95%

Study of incidence and risk factors of urinary tract infection in catheterised patients admitted at tertiary care

Kakaria¹,

Ashish²

2018

Int J Res Med Sci

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“…In present study pseudomonas was found 69.23% resistant to both ceftazidime and cefaperazone. 18,19 This shows that resistance among pseudomonas species has increased more over last 10 years. Highest resistance was found to aminoglycosides (tobramycin) 92.30%.…”

Section: Discussionmentioning

confidence: 95%

Study of incidence and risk factors of urinary tract infection in catheterised patients admitted at tertiary care hospital

Mangukiya¹,

Patel²,

Vegad

2015

Int J Res Med Sci

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“…Similarly out of 14 urine specimens, cefepime was effective in 8 (57.1%) isolates. In a study done by Patel et al, out of total 64 urinary isolates of Pseudomonas aeruginosa, resistance rate of cefepime was 15.6% [14].…”

Section: Discussionmentioning

confidence: 97%

In Vitro Efficacy of Cefepime Against Multi-Drug Resistant Pseudomonas aeruginosa � An Alarming Situation in our Setup

Satti¹,

Abbasi²,

Qumar³

et al. 2011

Open Drug R J

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Abstract:Background: Third generation cephalosporins are still most commonly used antibiotics empirically in our setup leading to emergence of resistance in this group. In this environment of increasing resistance, empirical use of this group of antibiotics would be a futile effort. Therefore, this study was conducted to evaluate the in vitro efficacy of fourth generation cephalosporin cefepime against multi-drug resistant isolates of Pseudomonas aeruginosa from various clinical specimens in our setup. Methodology: All the clinical specimens giving growth of Pseudomonas aeruginosa were included in the study. Modified Kirby-Bauer disk diffusion method was used for sensitivity testing. Isolates resistant to three or more than three groups of antibiotics were included in the final results. Place and Duration of Results:A total of 100 multi-drug resistant Pseudomonas aeruginosa isolates were cultured from various clinical specimens. Out of 100 isolates, 71% were resistant to cefepime while resistance rate of amikacin, gentamicin, ceftazidime, tazobactem/piperacillin, sulbactam/piperacillin, imipenem and polymyxin were 61%, 83%, 72%, 10%, 2%, 45% and 2% respectively. Conclusion:Drug resistance in Pseudomonas aeruginosa is alarming as it is now increasing even in newer generation of drugs. It is the need of hour to follow strict hospital infection control and antibiotic policies to halt the spread of this resistance.

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Antibiotic susceptibility pattern in urinary isolates of gram negative bacilli with special reference to AmpC β-lactamase in a tertiary care hospital

Cited by 19 publications

References 5 publications

Study of incidence and risk factors of urinary tract infection in catheterised patients admitted at tertiary care

Study of incidence and risk factors of urinary tract infection in catheterised patients admitted at tertiary care

Study of incidence and risk factors of urinary tract infection in catheterised patients admitted at tertiary care hospital

In Vitro Efficacy of Cefepime Against Multi-Drug Resistant Pseudomonas aeruginosa � An Alarming Situation in our Setup

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