Antibiotic use and the prevalence of antibiotic resistant bacteria on turkey farms

Chander, Yogesh; Gupta, Satish C.; Kumar, Kuldip; Goyal, Sagar M.; Murray, Helene

doi:10.1002/jsfa.3141

Cited by 14 publications

(11 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, antibiotic resistance can occur in bacteria even when antibiotics have not been used (Chander et al . ). Multidrug resistance in many bacterial species (e.g.…”

Section: Introductionmentioning

confidence: 97%

The survival of multidrug‐resistant bacteria in thermophilic and mesophilic anaerobic co‐digestion of dairy manure and waste milk

Beneragama

Iwasaki

Lateef

et al. 2012

Animal Science Journal

View full text Add to dashboard Cite

Anaerobic digestion is considered as a promising method to manage animal waste with antibiotic-resistant bacteria. Current research was conducted to investigate the survival of multidrug-resistant bacteria (MDRB) resistant to three groups of antibiotics: (i) cefazolin, neomycin, vancomycin, kanamycin (group 1); (ii) penicillin, oxytetracycline, ampicillin, streptomycin (group 2); and (iii) cefazolin, neomycin, vancomycin, kanamycin, penicillin, oxytetracycline, ampicillin, streptomycin (group 3), in anaerobic digestion of dairy manure and co-digestion of dairy manure and waste milk at 37°C and 55°C for 22 days, respectively. The population densities of three groups of MDRB on peptone, tryptone, yeast and glucose agar plates incubated at 30°C for 7 days before and after digestion showed 100% destruction in both digestates at thermophilic temperature. Overall reduction of more than 90% of three groups of MDRB was observed in mesophilic digestion with no significant differences (P > 0.05) between manure and milk mixture. Co-digestion of dairy manure and waste milk always produced significantly (P < 0.05) higher total gas and methane gas than digestion of manure alone at both temperatures. Gas production in each case was significantly (P < 0.05) higher in thermophilic digestion than in mesophilic digestion. The results demonstrate that thermophilic co-digestion of dairy manure and waste milk offers more benefits in terms of the environment and economy.

show abstract

“…However, antibiotic resistance can occur in bacteria even when antibiotics have not been used (Chander et al . ). Multidrug resistance in many bacterial species (e.g.…”

Section: Introductionmentioning

confidence: 97%

The survival of multidrug‐resistant bacteria in thermophilic and mesophilic anaerobic co‐digestion of dairy manure and waste milk

Beneragama

Iwasaki

Lateef

et al. 2012

Animal Science Journal

View full text Add to dashboard Cite

show abstract

“…Increased use of preventive therapeutic antimicrobials (e.g. chlortetracycline, spectinomycin, amoxycillin and enrofloxacin) that are similar to classes of antimicrobials used in human therapies, may have contributed to selection of resistant strains of Salmonella or mobilization of plasmids from other resistant intestinal organisms (Chander et al, 2008). Use of antimicrobials can also result in perturbation of protective intestinal flora thereby enhancing the colonization and persistence of Salmonella (Bauer-Garland et al, 2006;Sekirov et al, 2008).…”

Section: Increased Virulence or Resistance To Relevant Therapies For mentioning

confidence: 99%

Scientific Opinion on an estimation of the public health impact of setting a new target for the reduction ofSalmonellain turkeys

Publication¹

2012

EFSA Journal

View full text Add to dashboard Cite

The quantitative contribution of turkeys and other major animal‐food sources to the burden of human salmonellosis in the European Union was estimated. A ‘Turkey Target Salmonella Attribution Model’ (TT‐SAM) based on the microbial‐subtyping approach was used. TT‐SAM includes data from 25 EU Member States, four animal‐food sources of Salmonella and 23 Salmonella serovars. The model employs 2010 EU statutory monitoring data on Salmonella in animal populations (EU baseline survey data for pigs), data on reported cases of human salmonellosis and food availability data. It estimates that 2.6 %, 10.6 %, 17.0 % and 56.8 % of the human salmonellosis cases are attributable to turkeys, broilers, laying hens (eggs) and pigs, respectively. The top‐6 serovars of fattening turkeys that contribute most to human cases are S. Enteritidis, S. Kentucky, S. Typhimurium, S. Newport, S. Virchow and S. Saintpaul. Comparing the prevalence of Salmonella in turkey flocks reported in 2010 with a theoretical combined prevalence for S. Enteritidis and S. Typhimurium of 1 % (i.e. the transitional target), a reduction of 0.4 % in the percentage of turkey‐associated human salmonellosis cases would be achieved. However, when adjusting the combined prevalence of all serovars to 1 %, an 83.2 % reduction in the percentage of turkey‐associated human salmonellosis cases, equivalent to 2.2 % of all human salmonellosis cases, is expected. Uncertainty and data limitations are discussed, including recommendations on how these could be overcome. Vertical transmission of Salmonella as well as hatchery acquired Salmonella contamination originating from breeding stock are very important sources for Salmonella infection in turkeys, and therefore controlling Salmonella in breeding flocks as well as in rearing and fattening flocks is necessary to minimise Salmonella in turkeys at slaughter.

show abstract

“…Tetracycline‐resistant bacteria are ubiquitous in the environment, with or without animal antibiotic use (e.g., Gebreyes et al , 2006), although animal antibiotic use certainly selects for resistant strains. For example, in the United States, tetracycline‐ and tylosin‐resistant bacteria are found in manure from swine farms that are not using antimicrobials, as well as in field soils where manure is applied regularly; the prevalence does not differ among farms using versus not using antimicrobial feed additives for growth promotion (Chander et al , 2006). Smith et al (2007) reported that resistance of E. coli to tetracycline, sulfonamides, and streptomycin is common in broiler chickens whether or not they receive antibiotics.…”

Section: Tetracycline Resistance In the Environmentmentioning

confidence: 99%

Assessing Potential Human Health Hazards and Benefits from Subtherapeutic Antibiotics in the United States: Tetracyclines as a Case Study

Cox¹,

Popken²

2010

Risk Analysis

View full text Add to dashboard Cite

Many scientists, activists, regulators, and politicians have expressed urgent concern that using antibiotics in food animals selects for resistant strains of bacteria that harm human health and bring nearer a "postantibiotic era" of multidrug resistant "super-bugs." Proposed political solutions, such as the Preservation of Antibiotics for Medical Treatment Act (PAMTA), would ban entire classes of subtherapeutic antibiotics (STAs) now used for disease prevention and growth promotion in food animals. The proposed bans are not driven by formal quantitative risk assessment (QRA), but by a perceived need for immediate action to prevent potential catastrophe. Similar fears led to STA phase-outs in Europe a decade ago. However, QRA and empirical data indicate that continued use of STAs in the United States has not harmed human health, and bans in Europe have not helped human health. The fears motivating PAMTA contrast with QRA estimates of vanishingly small risks. As a case study, examining specific tetracycline uses and resistance patterns suggests that there is no significant human health hazard from continued use of tetracycline in food animals. Simple hypothetical calculations suggest an unobservably small risk (between 0 and 1.75E-11 excess lifetime risk of a tetracycline-resistant infection), based on the long history of tetracycline use in the United States without resistance-related treatment failures. QRAs for other STA uses in food animals also find that human health risks are vanishingly small. Whether such QRA calculations will guide risk management policy for animal antibiotics in the United States remains to be seen.

show abstract

Antibiotic use and the prevalence of antibiotic resistant bacteria on turkey farms

Abstract: BACKGROUND: A preliminary study was undertaken to compare the prevalence of antibiotic resistance bacteria (ARB) on turkey farms using either antibiotics sub-therapeutically (AU) or no antibiotics (NAU). Samples of manure, soil, and dog feces were collected from seven AU and six NAU farms.

Cited by 14 publications

References 21 publications

The survival of multidrug‐resistant bacteria in thermophilic and mesophilic anaerobic co‐digestion of dairy manure and waste milk

The survival of multidrug‐resistant bacteria in thermophilic and mesophilic anaerobic co‐digestion of dairy manure and waste milk

Scientific Opinion on an estimation of the public health impact of setting a new target for the reduction ofSalmonellain turkeys

Assessing Potential Human Health Hazards and Benefits from Subtherapeutic Antibiotics in the United States: Tetracyclines as a Case Study

Contact Info

Product

Resources

About