Antibiotic Use in Pediatric and Neonatal Intensive Care Units; Multicenter Point Prevalence Study

Tolunay, Orkun; Çelik, Ümit; Yücel, Gülperi; Çelik, Tamer; Mert, Mustafa Kurthan; Reşitoğlu, Salim; Özdemir, Ulaş; Narli, Nejat; Hanta, Deniz; Yapıcıoğlu, Hacer; Gülcan, Hande; Özcan, Kenan; Yıldızdaş, Dinçer; Tolunay, İlknur; Gökay, Naime; Kiraz, Kemal

doi:10.5152/ced.2014.1748

“…Günümüzde yeni antibiyotik keşfine dair çabalar, ciddi direnç oranları nedeni ile sıklıkla başarısızlıkla sonuçlanabilmektedir (12). Antibiyotiklere direnç gelişimini tamamen engellemek mümkün görünmemektedir ancak direnç gelişimini yavaşlatmak elimizdedir (13,14).…”

Section: Introductionunclassified

Çocuk Yoğun Bakım Ünitesindeki Hastane Enfeksiyonlarının Değerlendirilmesi

Celıloğlu¹,

Tolunay²,

Çelik³

et al. 2017

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Objective: In this study, we aimed to retrospectively investigate the frequency of healthcare-associated infections, infection sites, culture proven microorganisms and antibiotic resistance properties registered in the surveillance system, in our Pediatric Intensive Care Unit over the past five years. Material and Methods: The data of healthcare-associated infections detected in patients in our 12-bed pediatric intensive care unit, which are all third-level, were collected from January 1, 2012 to December 31, 2016 retrospectively. Infection rate and density were made. Culture proven microorganisms and antibiotic resistance properties were recorded. Results: The data of 2545 patients who were followed in the pediatric intensive care unit during the study period were collected. Mortality rate was 9%. The total number of in patient days was 20.696. The median age of the patients was 3 years (min: 2 months, max: 18 years). The total number of patients with health care-associated infection was 60, the infection rate was 2.36 and infection density was 2.89. Laboratoryproven bloodstream infection was detected in 15 patients and the rate of infection was 0.59 and the density was 0.72. In seven patients, central venous catheter-related bloodstream infection was observed and the rate of infection was 0.27 and the density was 0.33. In nine patients, catheter-related urinary tract infection was detected and the rate of infection was 0.35 and the density was 0.43. Ventilator-associated pneumonia was observed in 30 patients and the rate of infection was 1.18 and the density was 1.44. Isolated microorganisms were as follows: Pseudomonas aeruginosa in 17 cases, Acinetobacter baumannii in 14 cases, Klebsiella pneumoniae in 9 cases, Serratia marcescens in 5 cases, Escherichia coli in 4 cases, Candida albicans in 4 cases, coagulase negative ©Telif Hakkı 2017 Çocuk Enfeksiyon Hastalıkları Derneği-Makale metnine www.cocukenfeksiyon.org web sayfasından ulaşılabilir.

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“…Current, the efforts to discover new antibiotics frequently fail due to serious resistance rates (12). It seems as if complete prevention of resistance development to antibiotics is impossible however, we can slow down resistance development (13,14).…”

Section: Introductionmentioning

confidence: 99%

Assessment of Healthcare-Associated Infections in the Pediatric Intensive Care Unit

Celıloğlu¹,

Tolunay²,

Çelik³

et al. 2017

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Objective: In this study, we aimed to retrospectively investigate the frequency of healthcare-associated infections, infection sites, culture proven microorganisms and antibiotic resistance properties registered in the surveillance system, in our Pediatric Intensive Care Unit over the past five years. Material and Methods: The data of healthcare-associated infections detected in patients in our 12-bed pediatric intensive care unit, which are all third-level, were collected from January 1, 2012 to December 31, 2016 retrospectively. Infection rate and density were made. Culture proven microorganisms and antibiotic resistance properties were recorded. Results: The data of 2545 patients who were followed in the pediatric intensive care unit during the study period were collected. Mortality rate was 9%. The total number of in patient days was 20.696. The median age of the patients was 3 years (min: 2 months, max: 18 years). The total number of patients with health care-associated infection was 60, the infection rate was 2.36 and infection density was 2.89. Laboratory-proven bloodstream infection was detected in 15 patients and the rate of infection was 0.59 and the density was 0.72. In seven patients, central venous catheter-related bloodstream infection was observed and the rate of infection was 0.27 and the density was 0.33. In nine patients, catheter-related urinary tract infection was detected and the rate of infection was 0.35 and the density was 0.43. Ventilatorassociated pneumonia was observed in 30 patients and the rate of infection was 1.18 and the density was 1.44. Isolated microorganisms were as follows: Pseudomonas aeruginosa in 17 cases, Acinetobacter baumannii in 14 cases, Klebsiella pneumoniae in 9 cases, Serratia Özet Giriş: Bu çalışmada Çocuk Yoğun Bakım ünitemizde son beş yılda sürveyans sisteminde kayıtlı hastane enfeksiyonlarının sıklığı, enfeksiyon alanları, kültürlerde üretilen mikroorganizmalar ve antibiyotik direnç özelliklerinin geriye dönük olarak incelenmesi amaçlandı. Gereç ve Yöntemler: Tamamı üçüncü basamak olan 12 yataklı çocuk yoğun bakım ünitemizde 1 Ocak 2012-31 Aralık 2016 döneminde yatan hastalarda tespit edilen hastane enfeksiyonlarının verileri geriye dönük olarak toplandı. Enfeksiyon hızı ve dansite hesaplamaları yapıldı. Kültürlerde üretilen mikroorganizmalar ve antibiyotik direnç özellikleri kaydedildi. Bulgular: Çalışma periyodu boyunca çocuk yoğun bakıma yatırılarak tedavi edilmiş olan 2545 hastanın verileri toplandı. Mortalite oranı %9 idi. Yatan hasta gün sayısı 20.696 idi. Hastaların yaşları ortanca 3 yaş (min: 2 ay, maks: 18 yaş) idi. Toplam hastane enfeksiyonu olan hasta sayısı 60, enfeksiyon hızı 2.36 ve enfeksiyon dansitesi 2.89 idi. Laboratuvar ile kanıtlanmış kan dolaşımı enfeksiyonu 15 hastada saptandı ve enfeksiyon hızı 0.59, dansitesi 0.72 olarak hesaplandı. Yedi hastada santral venöz kateter ilişkili kan akımı enfeksiyonu gözlenmişti ve enfeksiyon hızı 0.27, dansitesi 0.33 bulunmuştu. Dokuz hastada kateter ilişkili üriner sistem enfeksiyonu saptanmıştı ve enfeksi...

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