Antibiotics disrupt lipid metabolism in zebrafish (Danio rerio) larvae and 3T3-L1 preadipocytes

A Novel Rare Earth and Covalent Organic Framework Composite for Rapid and Highly Sensitive Electrochemical Analysis of Sulfadiazine in Fish Muscle

“…This may lead to negative effects on all aspects of the environment [4]. For fish, Zhou et al found that SFZ exposure to water bodies has effects on the growth, antioxidant capacity, and thyroid hormones of non-target aquatic organisms (rana nigromaculata tadpoles) [5]; Deng et al found that SFZ enrichment in zebrafish was enantioselective, which would cause oxidative damage and induce enzyme activity in zebrafish (danio rerio) [6]; Jiang et al showed that zebrafish embryo development, gene expression, and larval body weight were affected by SFZ at ambient concentrations [7]; Lei et al have shown that SFZs disrupt lipid metabolism in zebrafish (danio rerio) larvae and 3T3-L1 preadipocytes [8]. Meanwhile, the risk of antibiotic resistance due to abuse cannot be ignored, which may produce new epizootics that are difficult to treat.…”