Antibiotics in dental implants: A review of literature

Surapaneni, Hemchand; Yalamanchili, Pallavi Samatha; Basha, Hafeez; Potluri, Sushma; Elisetti, Nirupa; Kumar, M. Kiran

doi:10.4103/0975-7406.191961

Cited by 38 publications

(12 citation statements)

References 15 publications

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“…This may be related to the belief of dentists that the use of antibiotics will reduce the graft or implant failure rate and that healing will accelerate 11 . On the other hand, some dentists see grafts and implants as foreign material to the body and that with the use of antibiotics, the primary response to these foreign materials will decrease and thus, less pain will be encountered 23 .…”

Section: Discussionmentioning

confidence: 99%

Antibiotic prescription practices of periodontology specialists in Turkey: A cross-sectional web-based questionnaire study

Yıldız¹,

Akgul²,

Günpınar³

2023

Popul. Med.

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INTRODUCTIONAntibiotic use is common in periodontal treatments for preventing postoperative infections. However, due to the need for more information about prescribing patterns amongst periodontists in Turkey, this study aimed to investigate the tendency of prescribing systemic antibiotics in Turkey. METHODS This survey was distributed to 108 periodontists in clinical practice at university/private clinics in Turkey in March-July 2020. Demographic characteristics of participants, their use of systemic antibiotics, and their type/dose/timing for surgical/non-surgical periodontal treatments were obtained. RESULTS In all, 55.6% of participants indicated that they prescribed antibiotics as adjunct to non-surgical periodontal treatment. Amoxicillin Clavulanic Acid (AMC) + Metronidazole (ME) combination was the most prescribed (48.3%) among others. Respondents were more likely to prescribe antibiotics for surgical periodontal therapy (77.8%), and most of them (66.7%) let patients take antibiotics after completion of surgical treatment, 29.8% both before and after surgery. AMC (63.1%) and AMC + ME (27.4%) were most prescribed for surgical periodontal treatment. Most of the participants prefer to advise systemic antibiotics following allogeneic (80%) or heterogeneous (57.4) tissue graft applications, and nearly half of them (42.6%) prescribed antibiotics after autogenous graft applications. CONCLUSIONS The prevalence of systemic antibiotic prescription was relatively high among periodontists in Turkey. These results are beneficial for the development of practice guidelines in Turkey. The necessity of having a guideline in using antibiotics in cases of periodontal disease, periodontal surgery and periimplantitis, has once again been demonstrated.

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Section: Discussionmentioning

confidence: 99%

Antibiotic prescription practices of periodontology specialists in Turkey: A cross-sectional web-based questionnaire study

Yıldız¹,

Akgul²,

Günpınar³

2023

Popul. Med.

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“…coli and osteomyelitis in diabetic patients with aggressive bilateral maxillary necrosis . Both of these bacteria are classified as opportunistic pathogens and are often associated with infections characterized by the formation of biofilms, which can lead to severe systemic infections . The antibacterial efficacy of the NO-releasing SNAP-PEG coating was evaluated using a zone of inhibition study.…”

Section: Methodsmentioning

confidence: 99%

“… 40 Both of these bacteria are classified as opportunistic pathogens and are often associated with infections characterized by the formation of biofilms, which can lead to severe systemic infections. 41 The antibacterial efficacy of the NO-releasing SNAP-PEG coating was evaluated using a zone of inhibition study. For this, E. coli was grown in LB media and S. mutans in BHI media until the mid-log phase and then diluted in sterile 10 mM PBS.…”

Section: Methodsmentioning

confidence: 99%

Engineering Nitric Oxide-Releasing Antimicrobial Dental Coating for Targeted Gingival Therapy

Chug,

Crutchfield,

Garren

et al. 2024

ACS Appl. Bio Mater.

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Bacterial biofilms play a central role in the development and progression of periodontitis, a chronic inflammatory condition that affects the oral cavity. One solution to current treatment constraints is using nitric oxide (NO)�with inherent antimicrobial properties. In this study, an antimicrobial coating is developed from the NO donor S-nitroso-N-acetylpenicillamine (SNAP) embedded within polyethylene glycol (PEG) to prevent periodontitis. The SNAP-PEG coating design enabled a controlled NO release, achieving tunable NO levels for more than 24 h. Testing the SNAP-PEG composite on dental floss showed its effectiveness as a uniform and bioactive coating. The coating exhibited antibacterial properties against Streptococcus mutans and Escherichia coli, with inhibition zones measuring up to 7.50 ± 0.28 and 14.80 ± 0.46 mm 2 , respectively. Furthermore, SNAP-PEG coating materials were found to be stable when stored at room temperature, with 93.65% of SNAP remaining after 28 d. The coatings were biocompatible against HGF and hFOB 1.19 cells through a 24 h controlled release study. This study presents a facile method to utilize controlled NO release with dental antimicrobial coatings comprising SNAP-PEG. This coating can be easily applied to various substrates, providing a user-friendly approach for targeted self-care in managing gingival infections associated with periodontitis.

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“…Infection is the leading cause of early implant failure [6,13,19,20]. Using antibiotics for dental implantscan prevent and reduce the risk of infection [7,[21][22][23][24][25]and produce a local sterile environment that bene ts wound healing and bone integration [4,5,26,27].…”

Section: Introductionmentioning

confidence: 99%

Antibiotic prophylaxis during oral implant surgery in Northwest China

Lin

Jiao

Huang

et al. 2023

Preprint

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Background There is still no consensus on prophylactic antibiotics in dental implants in China. This study aims to further understand the current status of prophylactic antibiotics in dental implants in China and to provide evidence-based data for the guidelines of prophylactic antibiotic use in dental implants. Methods This study is based on a cross-sectional study of a National dental implant specialist member. The questionnaire survey was conducted from April to December of 2021.It consisted of three parts:the basic information of respondents, the cognitive environment of using prophylactic antibiotics in dental implants in Northwest China, and the use of antibacterial in dental implants.The conclusion was drawn by statistical analysis of the questionnaire survey. Results A total of 318 dentists were surveyed. Approximately 65.41% of respondents generally prescribed antibiotics during dental implant surgery, 33.65% just prescribed antibiotics under certain circumstances,and 0.94% never prescribed antibiotics. The most frequently-used antibiotic classes were penicillin (such as amoxicillin), cephalosporin (such as cefazolin), and nitroimidazole (such as metronidazole). It is common to treat patients with a combination of antibiotics. Furthermore, 55.87% of respondents used antibiotics for more than 24 hours in common dental implants, and 85.08% used antibioticsin dental implants with bone grafts. Conclusions Since there are no standards for regulations about the choice of varieties, dosage, and course of prescribing antibiotics during dental implants, the use of prophylactic antibiotics is largely based on the experience of dentists. Therefore, it’s necessary to formulate guidelines for using antibiotics in dental implants, improve the standardization of antibiotics, and prevent overuse and bacterial resistance.

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Antibiotics in dental implants: A review of literature

Cited by 38 publications

References 15 publications

Antibiotic prescription practices of periodontology specialists in Turkey: A cross-sectional web-based questionnaire study

Antibiotic prescription practices of periodontology specialists in Turkey: A cross-sectional web-based questionnaire study

Engineering Nitric Oxide-Releasing Antimicrobial Dental Coating for Targeted Gingival Therapy

Antibiotic prophylaxis during oral implant surgery in Northwest China

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