Antibody prevalence against haemorrhagic fever viruses in randomized representative central African populations

Gonzalez, Jean-Paul; Josse, R.; Johnson, E. D.; Merlin, M.; Georges, A. J.; Abandja, J.; Danyod, M.; Delaporte, Eric; Dupont, Alain; Ghogomu, A.; Kouka-Bemba, D.; Madelon, M.C.; Sima, Alireza; Meunier, Danièle

doi:10.1016/s0923-2516(89)80112-8

Cited by 101 publications

(72 citation statements)

References 17 publications

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“…There have been no identified cases of active CCHFV infection in Cameroon, but two humans in the Far North region were seropositive for CCHFV in another study (Gonzalez et al 1989). CCHFV is an arbovirus in the family Bunyaviridae.…”

Section: Crimean-congo Hemorrhagic Fever Virusmentioning

confidence: 98%

“…Serosurveys have found humans seropositive for filoviruses in Cameroon, predominantly those living in southern tropical rainforest (Gonzalez et al 1989;Kuhn 2008). The seroprevalence of filoviruses in these studies in spite of scarce clinical evidence has led to speculation about nonspecific assay reactivity, false positives, or the presence of nonpathogenic filoviruses (Gonzalez et al 1989;Monath 1999).…”

Section: Ebola Virusmentioning

confidence: 99%

“…Serosurveys found two humans and Mastomys spp. seropositive for LASV in the Far North region of Cameroon (Gonzalez et al 1989). The Table 2 for details.…”

Section: Lassa Virusmentioning

confidence: 99%

“…The Table 2 for details. * putative lack of LASV infections in Central Africa despite the presence of the reservoir host species has led some to speculate that LASV is restricted to certain subspecies of Mastomys natalensis or that its niche is filled by arenaviruses that are nonpathogenic in humans (Gonzalez et al 1989). We identified three predictions for LASV from two publications (Fichet-Calvet and Rogers 2009; Mylne et al 2015).…”

Section: Lassa Virusmentioning

confidence: 99%

“…In 1987, a patient with an ongoing RVFV infection was anecdotally reported in the Far North region of Cameroon (Gonzalez et al 1989). Subsequently, serological evidence of past infection was found in humans in the Far North and Littoral regions and in livestock in the Far North, Adamaoua, Center, and South regions (Maurice 1967;Gonzalez et al 1989;LeBreton et al 2006).…”

Section: Rift Valley Fever Virusmentioning

confidence: 99%

See 4 more Smart Citations

Translating Predictions of Zoonotic Viruses for Policymakers

LeBreton¹,

Fuller

Hoffman

et al. 2017

EcoHealth

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Section: Crimean-congo Hemorrhagic Fever Virusmentioning

confidence: 98%

Section: Ebola Virusmentioning

confidence: 99%

“…Serosurveys found two humans and Mastomys spp. seropositive for LASV in the Far North region of Cameroon (Gonzalez et al 1989). The Table 2 for details.…”

Section: Lassa Virusmentioning

confidence: 99%

Section: Lassa Virusmentioning

confidence: 99%

Section: Rift Valley Fever Virusmentioning

confidence: 99%

See 3 more Smart Citations

Translating Predictions of Zoonotic Viruses for Policymakers

LeBreton¹,

Fuller

Hoffman

et al. 2017

EcoHealth

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Seroepidemiology of Hantaan virus infection in Taiwan

Kao

Chen²,

Yen³

et al. 1996

J. Med. Virol.

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In order to investigate the infection rate of Hantaan virus in Taiwan, a total of 6,536 human serum samples were collected from residents, selected by stratified random sampling, from 19 townships covering four different ethnic groups: Aborigines, Fukien Taiwanese, Hakka Taiwanese, and Mainland Chinese. Serum samples were screened for Hantaan virus antibodies by indirect immunofluorescence. The prototype Hantaan virus (76/118)-infected Vero E6 cells were used as the viral antigen for the antibody detection. Among 6,536 human serum samples, 403 (6.2%) samples had Hantaan virus antibodies. The seropositive rates for males and females were 6.1% and 6.2%, respectively. A higher seropositive rate was found among Aborigines on the Orchid Islets (11.5%) and Fukien Taiwanese on the Penghu Islets (11.6%), while the lowest rate was observed among Hakka Taiwanese in the south of Taiwan (2.5%). In comparing with different ethnic groups, the highest prevalence was found among Fukien Taiwanese (8.1%) and the lowest among Mainland Chinese (4.9%). Among the different geographical areas, the highest positive rate was found in western Taiwan (7.1%) and the lowest in southern Taiwan (5.4%). Hantaan virus antibodies were also detected in 22 of 548 (4.0%) rat serum samples. The highest seropositive rate was found in rat sera collected from the Orchid Islets (21.4%). None of the rat sera collected from Hsinchu, Miaoli, Changhua, Nantu, Yunlin, Chiayi, Tainan, and Penghu Counties were positive. Hantaan virus antibodies were found in rats: Rattus rattus (20%), Bandicota indica (9.0%), Rattus norvegicus (8.3%), Bandicota nemorivaga (6.3%), Rattus losea (4.2%), and Apodemus agrarius (1.6%). Hantaan virus antibodies were not detected in rat sera collected from species of Rattus coxinga, Rattus culturatus, Mus musculus, Mus caroli, Suncus murinus, and Apodemus semotus. The results show that the Hantaan or Hantaan-related virus exists and is distributed widely in both human and rats in Taiwan.

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Central Africa

Burchard¹,

Ehrhardt

2011

Infectious Diseases: A Geographic Guide

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Antibody prevalence against haemorrhagic fever viruses in randomized representative central African populations

Cited by 101 publications

References 17 publications

Translating Predictions of Zoonotic Viruses for Policymakers

Translating Predictions of Zoonotic Viruses for Policymakers

Seroepidemiology of Hantaan virus infection in Taiwan

Central Africa

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