Antibody Profiling of Bipolar Disorder Using Escherichia coli Proteome Microarrays

An automatic spot identification method is developed for high throughput surface plasmon resonance imaging (SPRi) analysis. As a combination of video accessing, image enhancement, image processing and parallel processing techniques, the method can identify the spots in SPRi images of the microarray from SPRi video data. In demonstrations of the method, SPRi video data of different protein microarrays were processed by the method. Results show that our method can locate spots in the microarray accurately regardless of the microarray pattern, spot-background contrast, light nonuniformity and spotting defects, but also can provide address information of the spots.

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Automatic Spot Identification Method for High Throughput Surface Plasmon Resonance Imaging Analysis

Wang

Huang

Cheng

2018

Biosensors

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Antibody Profiling of Bipolar Disorder Using Escherichia coli Proteome Microarrays

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Automatic Spot Identification Method for High Throughput Surface Plasmon Resonance Imaging Analysis

Automatic Spot Identification Method for High Throughput Surface Plasmon Resonance Imaging Analysis

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