Antibody to a mutagenic peptide of herpes simplex virus in young adult patients with cancer of the head and neck

Das, Chandra; Schantz, Stimson P.; Shillitoe, Edward J.

doi:10.1016/0030-4220(93)90235-v

Cited by 8 publications

(4 citation statements)

References 25 publications

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“…Factors that may account for oral cancer in young adults remain unknown. Suspected etiologic agents include smokeless tobacco, 10,11 various forms of drug abuse, 12 virus, 13 and host susceptibility factors. 14 However, no clear evidence exists to support the significance of any single determinant, including the role of tobacco.…”

mentioning

confidence: 99%

Head and Neck Cancer Incidence Trends in Young Americans, 1973-1997, With a Special Analysis for Tongue Cancer

Schantz¹,

Yu²

2002

Arch Otolaryngol Head Neck Surg

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302

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Objective: To examine the temporal changes in head and neck cancer in young adults in the United States.Methods: Using the cancer surveillance database from the National Cancer Institute Surveillance, Epidemiology, and End Results (SEER) Program, we calculated ageadjusted incidence rates for head and neck cancers. Using the joinpoint regression model, we described tongue cancer incidence trends and established the statistical significance of temporal changes. We also compared changes in 5-year survival rates for tongue cancer.Results: From 1973 to 1997, there were 63 409 patients with head and neck cancer in the 9 SEER registries. Of these, 3339 patients were younger than 40 years. The incidence of head and neck cancer remained stable in groups older than 40 years comparing the 1973-1984 and 1985-1997 data. In contrast, tongue cancer in adults younger than 40 years increased approximately 60% during the same period. We detected a significant increase (REPRINTED) ARCH OTOLARYNGOL HEAD NECK SURG/ VOL 128, MAR 2002 WWW.ARCHOTO.COM 268

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mentioning

confidence: 99%

Head and Neck Cancer Incidence Trends in Young Americans, 1973-1997, With a Special Analysis for Tongue Cancer

Schantz¹,

Yu²

2002

Arch Otolaryngol Head Neck Surg

Self Cite

302

196

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“…El estadio tumoral y la supervivencia se encuentra asociada, en algunos estudios, con un incremento de los anticuerpos IgM para VHS -1 24 . Sin embargo, en dichas serologías no se identifican otros anticuerpos únicos para los pacientes con cáncer, que no se presenten en el resto de los pacientes 25 .…”

Section: Discussionunclassified

Carcinoma escamoso de cavidad oral en paciente menor de edad

Saura

Jariod

Gavin

et al. 2017

Rev. Otorrinolaringol. Cir. Cabeza Cuello

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“…Patients with oral cancer have generally been exposed to HSV, as judged by the fact that most have antibodies to the virus. An earlier study showed that although their overall level of neutralizing antibody is similar to that of matched control subjects, some differences in the antibodies are seen; 33 the patients have higher levels of IgA antibodies to a protein present in cells that are infected by the virus and higher levels of IgM antibody to an antigen present on the virus particle. The viral antigens that are recognized by the patients' sera have not been identified.…”

Section: Herpes Simplex Virusmentioning

confidence: 92%

Role of viruses in oral squamous cell carcinoma

Metgud¹,

Astekar²,

Verma³

et al. 2012

Oncol Rev

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The etiology of oral squamous cell carcinoma (OSCC) is complex and involves many factors. The most clearly defined risk factors are smoking and alcohol, which substantially increase the risk of oral SCC. However, despite this clear association, a substantial proportion of patients develop OSCC without exposure to them, emphasizing the role of other risk factors such as genetic susceptibility and oncogenic viruses. Some viruses are strongly associated with OSCC while the association of others is less frequent and may depend on co-factors for their carcinogenic effects. Therefore, the exact role of viruses must be evaluated with care in order to improve the diagnosis and treatment of OSCC.

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Antibody to a mutagenic peptide of herpes simplex virus in young adult patients with cancer of the head and neck

Cited by 8 publications

References 25 publications

Head and Neck Cancer Incidence Trends in Young Americans, 1973-1997, With a Special Analysis for Tongue Cancer

Head and Neck Cancer Incidence Trends in Young Americans, 1973-1997, With a Special Analysis for Tongue Cancer

Carcinoma escamoso de cavidad oral en paciente menor de edad

Role of viruses in oral squamous cell carcinoma

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