Anticancer Activities of Plant Secondary Metabolites: Rice Callus Suspension Culture as a New Paradigm

Ramakrishna, Wusirika; Kumari, Anuradha; Rahman, Nafeesa; Mandave, Pallavi

doi:10.1016/j.rsci.2020.11.004

Cited by 35 publications

(19 citation statements)

References 131 publications

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“…49 These bioactive compounds exert anticancer effects independently or synergistically with other compounds through regulation of metabolic and signaling pathways, inhibition of enzymes vital for cancer progression, angiogenesis, microtubule assembly and induction of apoptosis. 50 (Figure 1)…”

Section: Anticancer Mechanisms Of Bioactive Compoundsmentioning

confidence: 99%

Potential Anticancer Activity of Bioactive Compounds from Ipomoea batatas

Silva-Correa¹,

Hilario-Vargas²,

Torre³

et al. 2022

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ANTICANCER EVALUATION OF SWEET POTATOSweet potato (Ipomoea batatas) is one of the world's most important food crops. Its leaves, stems, and tubers are consumed by an increasing number of people, especially in Asian countries, 18 because it plays an important role as a source of energy and phytochemicals in human nutrition. 19 Ipomoea batatas are characterized by the diversity of colors of the skin and roots that vary from white to yellow, orange and dark purple. The peels contain different

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Section: Anticancer Mechanisms Of Bioactive Compoundsmentioning

confidence: 99%

Potential Anticancer Activity of Bioactive Compounds from Ipomoea batatas

Silva-Correa¹,

Hilario-Vargas²,

Torre³

et al. 2022

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“…Over 200 novel chemical compounds have been licensed for use in the battle against cancer in the last 50 years, with about 50% being molecules of unaltered natural products [ 21 ]. Small organic molecules of secondary metabolites have played an essential role in inhibiting proliferation-induced apoptosis or other modifiable mechanisms [ 22 , 23 , 24 ]. Natural products and their derivatives have been recognized for many years by the pharmaceutical industry [ 25 , 26 ].…”

Section: The Activity Of Amg In Breast Cancermentioning

confidence: 99%

α-Mangostin Nanoparticles Cytotoxicity and Cell Death Modalities in Breast Cancer Cell Lines

et al. 2021

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α-Mangostin (AMG) is a potent anticancer xanthone that was discovered in mangosteen (Garcinia mangostana Linn.). AMG possesses the highest opportunity for chemopreventive and chemotherapeutic therapy. AMG inhibits every step in the process of carcinogenesis. AMG suppressed multiple breast cancer (BC) cell proliferation and apoptosis by decreasing the creation of cancerous compounds. Accumulating BC abnormalities and their associated molecular signaling pathways promotes novel treatment strategies. Chemotherapy is a commonly used treatment; due to the possibility of unpleasant side effects and multidrug resistance, there has been substantial progress in searching for alternative solutions, including the use of plant-derived natural chemicals. Due to the limitations of conventional cancer therapy, nanotechnology provides hope for effective and efficient cancer diagnosis and treatment. Nanotechnology enables the delivery of nanoparticles and increased solubility of drugs and drug targeting, resulting in increased cytotoxicity and cell death during BC treatment. This review summarizes the progress and development of AMG’s cytotoxicity and the mechanism of death BC cells. The combination of natural medicine and nanotechnology into a synergistic capital will provide various benefits. This information will aid in the development of AMG nanoparticle preparations and may open up new avenues for discovering an effective BC treatment.

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“…4,5 Useful bioactive substances are usually extracted directly from plants, as there is an increasing demand for these plants (especially medicinal plants), and the number of plants obtained by wild picking is limited, especially for the endangered medicinal plants. 6 Excessive development can even lead to their extinction. Moreover, the environment in some areas is not conducive to picking.…”

Section: ■ Introductionmentioning

confidence: 99%

Using the Strategy of Inducing and Genetically Transforming Plant Suspension Cells to Produce High Value-Added Bioactive Substances

Jia

Yan

et al. 2022

J. Agric. Food Chem.

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Plants can produce many functional bioactive substances. The suspension cell system of plants can be constructed based on its characteristics to realize the large-scale production of valuable products. In this review, we mainly talk about the main strategies, elicitation, and genetic transformation to improve the yield of active substances by using this system. Meanwhile, we focus on the challenges hiding in the practical application and the future prospects and provide new ideas and the theoretical basis for obtaining numerous bioactive substances from plants.

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Anticancer Activities of Plant Secondary Metabolites: Rice Callus Suspension Culture as a New Paradigm

Cited by 35 publications

References 131 publications

Potential Anticancer Activity of Bioactive Compounds from Ipomoea batatas

Potential Anticancer Activity of Bioactive Compounds from Ipomoea batatas

α-Mangostin Nanoparticles Cytotoxicity and Cell Death Modalities in Breast Cancer Cell Lines

Using the Strategy of Inducing and Genetically Transforming Plant Suspension Cells to Produce High Value-Added Bioactive Substances

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