Anticancer activity of liposomal bergamot essential oil (BEO) on human neuroblastoma cells

Celia, Christian; Trapasso, Elena; Locatelli, Marcello; Navarra, Michele; Ventura, Cinzia Anna; Wolfram, Joy; Carafa, Maria; Morittu, Valeria Maria; Britti, Domenico; Marzio, Luisa Di; Paolino, Donatella

doi:10.1016/j.colsurfb.2013.09.017

Cited by 132 publications

(74 citation statements)

References 41 publications

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“…In continuation to our studies [11][12][13][14][15][16][17][18][19][20][21] , we report herein, for the first time, a comparative study on phenolics and free anthraquinones multicomponent pattern of these two wild Turkish species, coupled to a biological and enzymatic inhibitory activities evaluation in order to justify a possible correlation between considered phenolics and free anthraquinones on observed biological and enzymatic activities.…”

Section: Introductionmentioning

confidence: 99%

Comparative study of biological activities and multicomponent pattern of two wild Turkish species: Asphodeline anatolica and Potentilla speciosa

Zengin

Menghini

Malatesta

et al. 2016

Journal of Enzyme Inhibition and Medicinal Chemistry

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The multicomponent pattern and biological characterization of plant material are essential for pharmaceutical field, in the food supplements quality control procedures and to all plant-based products. These nutrients often show valuable effects related to their consumption due to the occurrence of secondary metabolites that show useful properties on health. In this framework, researches performed on this topic play a central role for human health and drug development process. The aim of this study was to compare phenolics and free anthraquinones multicomponent pattern of two wild Turkish species: Asphodeline anatolica and Potentilla speciosa using validated high-performance liquid chromatography-photogiode array (HPLC-PDA) assays, coupled to biological evaluation. Even if some variances related to biological and enzymatic inhibition activities can be ascribed to other phytochemicals, the reported data support traditional use of Asphodeline anatolica and Potentilla speciosa roots as valuable natural font for the development of novel natural-derived drug formulations and/or food supplements with health and nutritional benefits.

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Section: Introductionmentioning

confidence: 99%

Comparative study of biological activities and multicomponent pattern of two wild Turkish species: Asphodeline anatolica and Potentilla speciosa

Zengin

Menghini

Malatesta

et al. 2016

Journal of Enzyme Inhibition and Medicinal Chemistry

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“…Among the many essential oils, carvacrol, thymol, eugenol and isoeugenol have been shown to have effective antimicrobial activity against a broad-spectrum of microorganisms (Gallucci et al, 2014). Despite the potential for medicinal uses, these antifungal compounds have poor bioavailability and bioabsorptivity due to their low water solubility (Celia et al, 2013). In addition, essential oils are susceptible to oxidation as well as light and heat degradation, thus reducing their stability and shelf-life (Turek and Stintzing, 2013).…”

Section: Introductionmentioning

confidence: 99%

Antifungal activity against Candida albicans of starch Pickering emulsion with thymol or amphotericin B in suspension and calcium alginate films

Cossu

Wang

Chaudhari

et al. 2015

International Journal of Pharmaceutics

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“…5-Methoxypsoralen (5-MOP, bergapten), a component of bergamot oil, can induce skin cancer elicited by UVA light [78]. Apart from its phototoxicity, there are also reports concerning its anticancer activity, too [79,80].…”

Section: Safety Of Essential Oils In Topical Applicationmentioning

confidence: 99%

Application of essential oils as natural cosmetic preservatives

Dreger

Wielgus

2013

Herba Polonica

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S u m m a r yNowadays, safety of chemical preservatives has been questioned by a big number of consumers. Traditionally used preservatives often cause skin irritation and lead to allergenic reactions. Growing demands for more natural and preservative-free cosmetics promoted an idea of the replacement of synthetic preservatives with essential oils (EOs) of antimicrobial properties. The antimicrobial effect of essential oil depends on content, concentration and interactions between the main active compounds. Effective preservatives should be characterized by a broad spectrum of antimicrobial activity at a minimum concentration. Formulations containing both types of preservatives: essential oil and a synthetic one have been tested and proposed as a compromise that allows for reducing concentration of both components due to their synergistic activity. Although most essential oils are regarded as safe, some of them may cause risk of contact allergy or phototoxic reaction. A well balanced risk-benefit assessment of essential oils is one of the great challenges for scientists or health policy authorities. This paper presents current state of knowledge on essential oils focused on their antimicrobial properties, the assessment of their efficacy and safety as cosmetic preservatives.

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Anticancer activity of liposomal bergamot essential oil (BEO) on human neuroblastoma cells

Cited by 132 publications

References 41 publications

Comparative study of biological activities and multicomponent pattern of two wild Turkish species: Asphodeline anatolica and Potentilla speciosa

Comparative study of biological activities and multicomponent pattern of two wild Turkish species: Asphodeline anatolica and Potentilla speciosa

Antifungal activity against Candida albicans of starch Pickering emulsion with thymol or amphotericin B in suspension and calcium alginate films

Application of essential oils as natural cosmetic preservatives

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