Anticardiolipin Antibodies and Risk of Ischemic Stroke and Transient Ischemic Attack

Janardhan, Vallabh; Wolf, Philip A.; Kase, Carlos S.; Massaro, Joseph M.; D’Agostino, Ralph B.; Franzblau, Carl; Wilson, Peter W.F.

doi:10.1161/01.str.0000117575.48205.2d

Cited by 106 publications

(78 citation statements)

References 22 publications

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“…[689][690][691][692][693][694] In a case-control study of 255 patients with a mean age of 66 years, the presence of an anticardiolipin antibody was associated with a significantly increased risk for ischemic stroke (adjusted OR, 2.31; 95% CI, 1.09-4.90). 695 These findings were not replicated in a subsequent prospective cohort study that was part of WARSS.…”

Section: Antiphospholipid Antibodiesmentioning

confidence: 99%

Guidelines for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack

Kernan¹,

Ovbiagele²,

Black³

et al. 2014

Stroke

4,000

1,326

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The aim of this updated guideline is to provide comprehensive and timely evidence-based recommendations on the prevention of future stroke among survivors of ischemic stroke or transient ischemic attack. The guideline is addressed to all clinicians who manage secondary prevention for these patients. Evidence-based recommendations are provided for control of risk factors, intervention for vascular obstruction, antithrombotic therapy for cardioembolism, and antiplatelet therapy for noncardioembolic stroke. Recommendations are also provided for the prevention of recurrent stroke in a variety of specific circumstances, including aortic arch atherosclerosis, arterial dissection, patent foramen ovale, hyperhomocysteinemia, hypercoagulable states, antiphospholipid antibody syndrome, sickle cell disease, cerebral venous sinus thrombosis, and pregnancy. Special sections address use of antithrombotic and anticoagulation therapy after an intracranial hemorrhage and implementation of guidelines.

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Section: Antiphospholipid Antibodiesmentioning

confidence: 99%

Guidelines for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack

Kernan¹,

Ovbiagele²,

Black³

et al. 2014

Stroke

4,000

1,326

View full text Add to dashboard Cite

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“…621 The study included 2712 women (mean age, 59.3 years) and 2262 men (mean age, 58.3 years) who were free of stroke or TIA at the time of their baseline examination. An enzyme-linked immunosorbent assay (ELISA) was used to measure aCL from stored frozen sera.…”

Section: Hypercoagulabilitymentioning

confidence: 99%

Guidelines for the Primary Prevention of Stroke

Goldstein¹,

Bushnell²,

Adams³

et al. 2011

Stroke

1,300

577

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Background and Purpose-This guideline provides an overview of the evidence on established and emerging risk factors for stroke to provide evidence-based recommendations for the reduction of risk of a first stroke. Methods-Writing group members were nominated by the committee chair on the basis of their previous work in relevant topic areas and were approved by the American Heart Association (AHA) Stroke Council Scientific Statement Oversight Committee and the AHA Manuscript Oversight Committee. The writing group used systematic literature reviews (covering the time since the last review was published in 2006 up to April 2009), reference to previously published guidelines, personal files, and expert opinion to summarize existing evidence, indicate gaps in current knowledge, and when appropriate, formulate recommendations using standard AHA criteria (Tables 1 and 2). All members of the writing group had the opportunity to comment on the recommendations and approved the final version of this document. The guideline underwent extensive peer review by the Stroke Council leadership and the AHA scientific statements oversight committees before consideration and approval by the AHA Science Advisory and Coordinating Committee. Results-Schemes for assessing a person's risk of a first stroke were evaluated. Risk factors or risk markers for a first stroke were classified according to potential for modification (nonmodifiable, modifiable, or potentially modifiable) and strength of evidence (well documented or less well documented). Nonmodifiable risk factors include age, sex, low birth weight, race/ethnicity, and genetic predisposition. Well-documented and modifiable risk factors include hypertension, exposure to cigarette smoke, diabetes, atrial fibrillation and certain other cardiac conditions, dyslipidemia, carotid artery stenosis, sickle cell disease, postmenopausal hormone therapy, poor diet, physical inactivity, and obesity and body fat

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“…The prevalence of stroke in Nigeria is on the increase.6, 7 Osuntokun et al6 reported a crude prevalence of 58 per 100,000 of the population and Danesi et al 7 in a more recent studies reported a rate of 1.14 per 1,000. It is principally a disease of the elderly 8 however there is an increase in the prevalence of stroke in younger age group 9,10 . Stroke is a devastating event because of the consequent physical and psychological stress, economic loss to families and to the nation especially when young people are affected.…”

Section: Introductionmentioning

confidence: 99%

Antiphospholipid Antibodies In Adults With Ischaemic Stroke Seen At The University of Benin Teaching Hospital, Benin City, Nigeria

Nwogoh¹,

Augustina²,

Olubunmi³

et al. 2014

IOSRJDMS

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Anticardiolipin Antibodies and Risk of Ischemic Stroke and Transient Ischemic Attack

Cited by 106 publications

References 22 publications

Guidelines for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack

Guidelines for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack

Guidelines for the Primary Prevention of Stroke

Antiphospholipid Antibodies In Adults With Ischaemic Stroke Seen At The University of Benin Teaching Hospital, Benin City, Nigeria

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