2000
DOI: 10.1016/s0021-9150(00)80884-9
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Anticardiolipin antibodies are not an independent risk factor for stroke: An incident case referent study

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Cited by 17 publications
(23 citation statements)
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“…Several prospective, large-scale series have been conducted, with somewhat mixed results [3][4][5][6][7][8][9][10]. The discrepancy of the results could be explained by methodologic differences between studies such as the type and titer of aPL studied, sample size, and population studied [11].…”
Section: Antiphospholipid Antibodies and Stroke Riskmentioning
confidence: 99%
“…Several prospective, large-scale series have been conducted, with somewhat mixed results [3][4][5][6][7][8][9][10]. The discrepancy of the results could be explained by methodologic differences between studies such as the type and titer of aPL studied, sample size, and population studied [11].…”
Section: Antiphospholipid Antibodies and Stroke Riskmentioning
confidence: 99%
“…[293][294][295][296][297][298][299][300][301][302] The mechanism by which aPLs may lead to thrombosis is uncertain, but they appear to interfere with endogenous anticoagulants, protein C, and platelet homeostasis. [293][294][295][296][297][298][299][300][301][302] The mechanism by which aPLs may lead to thrombosis is uncertain, but they appear to interfere with endogenous anticoagulants, protein C, and platelet homeostasis.…”
Section: Antiphospholipid Antibody Syndromementioning
confidence: 99%
“…No significant differences in aCL titers were found when comparing 100 apparently healthy adult men subsequently developing an ischemic stroke with 100 well-matched controls; whereas aCL titers were significantly associated with subsequent deep vein thrombosis and pulmonary embolism in the Physician's Health Study [11]. More recently, in an incident casereferent study nested within the MONICA and Swedish Västerbotten cohort, IgM isotype aCL was found to be associated with future stroke but did not constitute an independent risk factor after adjusting for conventional vascular risk factors [26].…”
Section: Focal Cerebral Ischemiamentioning
confidence: 99%