2007
DOI: 10.1093/humrep/dem179
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Anticardiolipin antibody levels in women undergoing first in vitro fertilization/embryo transfer

Abstract: Our results indicate that IVF treatment increases IgG-aCL levels in patients with endometriosis and TF, but their presence seems to have no clinical relevance.

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Cited by 18 publications
(11 citation statements)
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References 47 publications
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“…We showed that aLN-I levels detected at T2 were significantly higher in comparison with those found at TO and Tl and this finding parallels our previous results on APA in infertile women undergoing IVF (15).…”
Section: Discussionsupporting
confidence: 90%
See 1 more Smart Citation
“…We showed that aLN-I levels detected at T2 were significantly higher in comparison with those found at TO and Tl and this finding parallels our previous results on APA in infertile women undergoing IVF (15).…”
Section: Discussionsupporting
confidence: 90%
“…In a previous study dealing with the presence and clinical relevance of antiphospholipid antibody (APA) in infertile women undergoing IVF, we demonstrated significantly increasedAPAlevels after IVF treatment and we hypothesized a possible role of hyperestrogenism in rising auto-Ab production (15). Since an interesting issue could be whether other auto-Abs are involved in this phenomenon, a further aim of this study is to analyze the effect of IVF treatment on aLN-1 levels.…”
mentioning
confidence: 94%
“…This is in agreement with previous study reported that ACL IgM was detected in women with secondary infertility [12]. It has been a speculated that ACL IgM antibody may be associated with repeated in vitro fertilization/embryo transfer failures [15] [24] [25]. Furthermore, the occurrence of ACL antibodies in almost every second woman suffering from endometriosis suggests existing of autoimmunologic basis of the secondary infertility [26].…”
Section: Discussionsupporting
confidence: 92%
“…8-10,17-46 All studies used IVF as ART, with 6 studies reporting intracytoplasmic sperm injection in adjunction. 9,23,[29][30][31]36 In 2 studies, patients received antiplatelet agents during ART. 22,46 Overall, the methodologic quality in case-control studies was poor (Tables 1-2).…”
Section: Resultsmentioning
confidence: 99%
“…One cohort study prospectively assessed the ART outcome in 50 patients with and without anti-cardiolipin antibodies and found no association with viable pregnancy (RR ϭ 0.59; 95% CI, 0.05-7.08) or pregnancy test results (RR ϭ 0.49; 95% CI, 0.19-1.28). 30 None of the other individual antibodies was evaluated in cohort studies.…”
Section: Anti-phospholipid Antibody Subtypesmentioning
confidence: 99%