2021
DOI: 10.1016/j.ijscr.2021.106027
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Anticoagulant-induced hemorrhagic cholecystitis with hemobilia after deceased donor kidney transplant and literature review

Abstract: Introduction and importance Hemobilia and hemorrhagic cholecystitis are uncommon causes of right upper quadrant abdominal pain. The development of intra-gallbladder and biliary bleeding has been primarily associated with abdominal trauma, malignancy, liver transplant, and iatrogenic injury to the biliary tree and vasculature. Spontaneous anticoagulant induced hemorrhagic cholecystitis and hemobilia are incredibly rare events and have only been documented by a handful of case reports. … Show more

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Cited by 3 publications
(3 citation statements)
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“…In our patient case, hemorrhagic cholecystitis occurred within 1 month after apixaban initiation. Other case reports showed a wide range of such occurrence, ranging from 24 hours [ 1 ], 27 days following initiation after cardiac surgery [ 8 ], and up to 6 weeks [ 7 ]. In the prior case reports, clinical presentations also varied, with some patients presenting with fever and pain radiating to the back, which was not observed in our patient.…”
Section: Discussionmentioning
confidence: 99%
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“…In our patient case, hemorrhagic cholecystitis occurred within 1 month after apixaban initiation. Other case reports showed a wide range of such occurrence, ranging from 24 hours [ 1 ], 27 days following initiation after cardiac surgery [ 8 ], and up to 6 weeks [ 7 ]. In the prior case reports, clinical presentations also varied, with some patients presenting with fever and pain radiating to the back, which was not observed in our patient.…”
Section: Discussionmentioning
confidence: 99%
“…Hemorrhagic cholecystitis is a rare cause of abdominal pain, which can result from malignancy, bleeding, or trauma [ 1 ]. The incidence of hemorrhagic cholecystitis is estimated at 3.5% of all reported cholecystitis cases, with mortality rates of 15–20% [ 2 ].…”
Section: Introductionmentioning
confidence: 99%
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