The prevalence and risk of metabolic syndrome and its components among people with posttraumatic stress disorder: A systematic review and meta-analysis, Metabolism (2015Metabolism ( ), doi: 10.1016Metabolism ( /j.metabol.2015 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.A C C E P T E D M A N U S C R I P T Random effects meta-analysis with a relative risk, subgroups and meta-regression analyses were employed.Results: Overall, 9 studies met the inclusion criteria including 9,254 individuals in midlife with PTSD and 6,852 general population controls. Conclusions: MetS is highly prevalent in people with PTSD. Routine screening and multidisciplinary management of medical and behavioral conditions is needed. Future
A C C E P T E D M A N U S C R I P T ACCEPTED MANUSCRIPTresearch should focus on how cardio-metabolic outcomes are moderated by clinical and treatment characteristics and genetic factors.